2BO3 Readings List Lodish 9th Edition F2021 PDF

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Biology textbook "Molecular Cell Biology" 9th edition readings...

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Biology 2B03

Fall 2021 READING LIST

RELEVANT REFERENCES FROM: LODISH ET AL, MOLECULAR CELL BIOLOGY. 9th EDITION. Module 1 Chapter 2 2.2 Chemical building blocks – amino acids pp 44-54 Chapter 3 pp. 70-115 3.1. Hierarchical structure of proteins. 3.2. Protein Folding. 3.3. Protein binding and enzyme catalysis. 3.4 Regulating protein function. Module 2: Characterizing proteins Chapter 3 – 3.5. Purifying, detecting, and characterizing proteins. pp. 116-132 Module 3: Biomembranes & cell architecture Chapter 4 - 4.2 Visualizing cell architecture: Light microscopy. pp. 148-166 Chapter 10 Biomembrane Structure 10.1 The lipid bilayer. pp. 442-454. 10.2 Membranes proteins. pp. 455-464. 10.3 Phospholipids pp 464-649

Module 4: Protein targeting – where do proteins go and how do they get there? Chapter 13 pp. 576-621 13.1 Targeting proteins (via ER) 13.2 Insertion of membrane proteins into the ER. 13.3 Protein modification, folding, quality control in the ER. 13.4 Targeting proteins to the mitochondria. 13.5 Targeting of Peroxisomal proteins. 13.6 Transport into and out of the nucleus. Module 5: Leaving the cell – secreted proteins Chapter 14 pp 622-660 14.1 Techniques for studying the secretory pathway. 14.2 Molecular mechanisms for vesicle budding and fusion. 14.3 Early stages of the secretory pathway. 14.4 Later stages of the secretory pathway. 14.5 Receptor-mediated endocytosis. 14.6 Directing membrane proteins and cytosolic materials to the lysosomes. Module 6: Signal Transduction Chapter 15 Signal Transduction and G Protein – Coupled Receptors. 15.1 Signal transduction: from extracellular signal to cellular response. pp 663- 669 15.2 Studying cell-surface receptors and signal transduction proteins pp 670-675 15.3 G Protein-coupled receptors. pp 676-681 15.4 G protein-coupled receptors/adenylate cyclase pp 683-689 Chapter 16 Signaling pathways that control gene expression. 16.1 Receptor Tyrosine Kinases. pp 709-714 16.2 Ras/MAP kinase pathways. pp 716-723 16.4 JAK/STAT Signalling pathway pp727-732 Module 7: cytoskeleton Chapter 17 17.1 Actin filaments p755 – 757 17.5 on myosin pp 773-777 17.6 Myosin-powered movements. Pp 780785 Chapter 18

18.1 Microtubules on structure. Pp 797 18.2 Microtubules on dynamics. Pp 802-805 18.4 Kinesin and dynein. pp 809-819

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