Biochemistry practice problems PDF

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1. Calculate the pH of the following: a. 5 x 10-4 M HCl b. 7 x 10-5 M NaOH c. 2 uM HCl d. 3 x 10-2 M KOH e. 0.04 mM HCl f. 6 x 10-9 HCl

2. Chloroacetic acid (ClCH2COOH) has a pKa of 2.87. What are: a. [H3O+] b. pH c. [ClCH2COO-] d. [ClCH2COOH] in 1.25 M ClCH2COOH?

3. The components of poison ivy and poison oak that produce the characteristic itchy rush are catechols substituted with long chain alkyl groups (pKa = 8.0).

If you were exposed to poison ivy, which of the treatments below would you apply to the affected area? Justify your choice. a. Wash the area with cold water b. Wash the area with dilute vinegar or lemon juice c. Wash the area with soap and water d. Wash the area with soap, water and baking soda (sodium bicarbonate)

4. Which of these compounds would be the best buffer at pH 5.0: formic acid (pKa = 3.8), r ethylamine (pKa = 9.0)? Why?

5. If the internal pH of a muscle cell is 6.8, what is the [HPO42-]/[H2PO4-] ratio in the cell? pKa of H2PO4 is 6.86.

6. At 37 C, if the plasma pH is 7.4 and plasma concentration of HCO3- is 15 mM, what is the plasma concentration of H2CO3? (pKa = 3.77).

7. Calculate the concentration of lactate in blood plasma (pH = 7.4) if the concentration of lactic acid is 1.5 uM. (pKa = 3.86)

8. On the basis of the following figure, what will be the pH of the acetate-acetic acid solution when the ration of [acetate]/ [acetic acid] is 10?...