Biol 319 Spring 2018 Vs 1 PDF

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Department of Biological Sciences, Binghamton University https://www.binghamton.edu/biology/

Biol 319 Pre-Health Microbiology Spring 2018 Syllabus Course Instructor: Cláudia N. H. Marques Office: Biotechnology Building BI2403 Office hours: Mondays 2-4 pm EST Office Telephone: +1-607-777-5755 Email: [email protected] Teaching Assistant: Courtney Kleeschulte Office: Biotechnology Building BI2208 Office hours: Tuesdays 11 am - 12 pm. Email: [email protected] Teaching Assistant: Amanda Zdimal Office: Biotechnology Building BI2208 Office hours: Fridays 11 am - 12 pm Email: [email protected] Email TAs, 24 hours in advance, if you are planning to attend their office hours. There are no walk-ins for TA office hours. Course Supports: Any problems with blackboard contact the helpdesk (click on the help link on the top right of my courses). If on campus: Walk-in: Located in The Technology Hub first floor lobby - (See Map) Call: 607-777-6420 E-mail: [email protected]. Spring Hours: Monday - Thursday 8 AM - 9 PM; Friday 8 AM - 4 PM.

Communication Policy Announcements will be posted on blackboard as needed. Students should contact me by email or during my office hours. I spend most of my time in my research laboratory so, please do not contact me by phone. If you do contact me by phone, please be sure to leave a message with your name, I will answer by email. Emails will be answered within 24 hours, except for weekends. I will only answer emails until 10AM on Saturdays so, if you email after 10AM on Saturday you will only receive an answer email by Monday morning.

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Course Information Description This course is directed to students interested in microbiology with an emphasis in health-related issues. Introduces the structure, physiology, genetics, ecology, and the evolution of microorganisms. Considering the increasing the detrimental effect of microbes to our health, with infectious diseases being one of the major causes of morbidity and mortality in the developing and developed world, special attention is given to the role of microbes in infectious diseases. Chemotherapeutic and immune control of infectious diseases are also discussed in detail. The course follows a sequence of development. We will first study the nature of microorganisms from the perspective of where microorganisms fit in life. The structure of prokaryotic and eukaryotic cells will be addressed. A “typical” prokaryotic cell and its component parts will be discussed. In each case, the function of teach cell component will be related to its importance in infectious diseases - for example, the selective action of antimicrobials, resistance to phagocytosis, development of vaccines or diagnosis of disease. Microbial genetics will be discussed in sufficient depth to understand the development and spread of antimicrobial resistance and, the emergence and re-emergence of infectious diseases. The principles of epidemiology, general health and the impact of the environment on infectious disease will be discussed and put into context to the impact of current public health. In addition, the immune system, its role in the host-parasite relationship, and its importance in the prevention and treatment of infectious disease will be discussed. The organ system approach to infectious disease rather than the infectious agent approach will be emphasized in this section. Finally, the most important and interesting infectious agents and related diseases will be addressed. Case histories will be used to assist in a practical understanding of disease and in problem solving. The etiology, pathogenesis, epidemiology, treatment, prevention and control of infectious diseases will be discussed. The global impact of infectious diseases will be addressed throughout the course.

Course Objectives By the end of this course students should be able to: • Distinguish microbiota and pathogens • Categorize the bacterial diversity, viral diversity and the diversity of the eukaryotic microorganisms • Describe the basic concepts of epidemiology and why is it important in infectious diseases • Distinguish among the various antimicrobials and their mode of action • Discern and identify various infectious agents related to diseases of various body systems • Understand and describe the microbial mechanisms of pathogenicity • Describe bacterial genetics and evolution • Identify the basic principles of innate and adaptive immunity

General Education Information This course does not have a general education course designation.

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Prerequisite(s) Biol 118, and Chem 102, Chem 107 or Chem 108. Students need to know the basics of DNA replication, transcription and translation. Students should also know the components of eukaryotic cells.

Relationship to Other Courses This course is a pre/co-requisite for Biol 329, Pre-Health Microbiology Lab.

Format and Procedures The course is composed by lectures, discussion, reading assignments, and homework.

Lecture and Lecture notes Lectures in this course will be one hour long, three times per week. Following each lecture, students are expected to look over the lecture material and complete any missed material with the textbook. The lectures are keyed to the book chapters. Lecture notes will be available on the weekly content of myCourses 12 hours before the lecture. Lecture notes will be in a PDF format with 2 slides per page.

Discussion Discussion topics or in course material to be discussed will be provided 1 week in advance under weekly content on the discussion section of myCourses. Once the lecture material starts to cover infectious diseases, several clinical cases will be discussed. Each student will be expected to submit 1 question per week relating to the material for the discussion. The questions need to be submitted by 2:20 pm on the Thursday, 24 hours before the weekly discussion. Discussion questions are submitted through my Courses on the discussion section.

Course Requirements Required Text Book Good news: your textbook for this class is available for free online, in web view and PDF format! You can also purchase a print version, if you prefer, via the campus bookstore or from OpenStax on Amazon.com. You can use whichever formats you want. Web view is recommended -- the responsive design works seamlessly on any device. If you buy on Amazon, make sure you use the link on your book page on openstax.org so you get the official OpenStax print version. (Simple printouts sold by third parties on Amazon are not verifiable and not as high-quality.) Microbiology from OpenStax, ISBN 1938168143, http://www.openstax.org/details/microbiology

Required Materials ●

Iclicker Every student must have a clicker to be purchased or rented from the bookstore (or other source, including from students that do not need it anymore - make sure that the

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ID number is clearly visible). Each student is responsible for bringing the clicker to every discussion class and to make sure the batteries work. Internet Blackboard access Adobe Reader - http://get.adobe.com/reader/ Adobe Flash Player - http://get.adobe.com/flashplayer/

Recommended Texts & Other Readings ●

Other readings will be made available in myCourses under the weekly contents in the Folder Readings of the week.

Credit Hours and Expectations This course is a 4-credit course, which means that students are expected to do at least 12.5 hours of course-related work or activity each week during the semester. This includes scheduled class meeting times as well as time spent completing assigned readings, studying for tests and examinations, preparing written assignments, and other course-related tasks.

Assignments Assignments will be given as review questions, discussion assigned videos and reading, discussion sessions, assigned reading materials, and an essay on infectious diseases.

Examinations Overall there will be 3 exams in this course. Two of the exams will be during the semester and the final exam will be during finals week. None of the exams will be cumulative.

Discussion Topics Weekly discussions will be held on myCourses. Discussion topics or in course material to be discussed will be provided 1 week in advance. This material will be in the form of video material to be evaluated and debated. Each student will be expected to: submit a question per discussion 24 hours before the discussion session (AKA each Thursday by 2:20 pm), and to attend the discussion and answer a minimum of 80% of the clicker questions, including the initial attendance question. Lack of answering the initial attendance question will be considered as a lack of attendance discussion.

Homework Assignments There will be several homework assignments throughout the semester. Homework will be available through myCourses. Homework will have clear stated deadlines. If a deadline is missed, the assignment will receive a grade of zero. The usual deadline for homework is 2 weeks, once it is posted. You will have 2 attempts to complete the homework. There will be no make-up homework.

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Essay There will be one essay where students will have to provide information on the etiology and history of 1 infectious disease. The infectious disease will be assigned to each student by March 2nd. Information needed to be provided in the essay includes name of the disease, name and description of the infectious agent(s), when was is first described, mode(s) of transmission, treatment, epidemiology, diagnosis, and prevention. Essays need to be submitted through myCourses on the lecture section, under weekly content, sub-heading essay.

Grading Grading for the course will be broken down as follows: Assignment Name

Percent of Total

Exam 1

12%

Exam 2

15%

Exam 3

20%

Essay

10%

Lecture attendance

1%

Homework

20%

Discussion

22%

Lecture participation will be recorded using Iclicker. During lecture, there might be 1 or 2 questions. Attendance recording will be random. Students need to be present during at least 10 lectures where attendance is taken. Discussions' total 22% grade will be divided equally per discussion thus consisting of 2% each discussion. Each discussion grading will consist of 40% posted question and 60% presence during discussion and answering 80% of clicker questions.

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Grading Scheme Grades are based on percent numeric score: Grade

Percent

Grade

Percent

A

94 – 100%

C+

77 -...