Biomolecules quiz PDF

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Biomolecules quiz answers...

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Biomolecules/Biopolymers Quiz 1. Match the biomolecule to the biopolymer a. Lipids- no polymer b. Amino acids- proteins c. Carbohydrates- polysaccharides d. Nucleic acids- DNA or RNA 2. Match the biopolymer to the linkage (bond type) that connects the individual units of the polymer or aggregate a. Proteins- peptide bond b. DNA- phosphodiester bond c. Carbohydrates- glyosidic bond d. Lipids- van der Walls bonds 3. The molecules below are ________ which means they are non-superimposable. a. Answer: enantiomers, chiral 4. Most lipids are hydrophobic, however some have hydrophobic and hydrophilic parts. What term describes this molecules? a. Answer: amphipathic 5. Unsaturated lipids ___________ the melting temperature/transition temperature of a membrane. a. Answer: lower 6. Three lipids will form __________ linkages with glycerol to form a triacylglycerol molecule. a. Answer: ester 7. Cold water salmon have distinct levels of cholesterol in their cell membranes compared to their warm water cousins and even cold water salmon living in different bodies of water have distinct levels of cholesterol. Why? a. Answer: Modulating cholesterol alters flexibility and fluidity of cell membrane 8. Which type of interaction does base stacking most resemble? a. Answer: London dispersion force 9. Which molecule would be most likely to disrupt base stacking interactions? a. Answer: a planar aromatic molecule 10. Load structure 1BNA into YASARA (File>Load PDB>from internet, then 1BNA and click OK) Look at the distance between bases and the geometry before answering the questions below. What specific groups form the base stacking interactions in DNA? a. Answer: nucleotide base 11. If two bases in a DNA molecule were moved away from the parallel orientation in DNA such that one base was 45 degrees relative to the other base, would the interaction energy increase, decrease or stay the same? a. Answer: decrease

12. Now load Z-form DNA into YASARA using the command above but with the PDB ID 4FS5. Compare the base stacking in 1BNA to 4FS5. Remember who can hide a molecule by clicking on the Yes/No in the Vis column to the right of the screen. Also you can change the view using the F keys at the top of the keyboard. You can hide waters by pressing the spacebar and typing HideRes HOH and pressing enter. Which form of DNA likely has better base stacking interactions? a. Answer: B-form 13. Which aspect of DNA is distinct between the two forms of DNA and may affect the stability of the structure? a. Answer: bases do not stack in Z-form DNA...