BIOS 255 Week 4 Lab Questions-Histologic analysis of immune system tissues PDF

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This lab included us having to label the following on the document....

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BIOS 255 – Week 4 Lab Instructions

BIOS 255 Week 4 Lab Instructions Activity Description Points Part 1 Histologic analysis of immune system tissues Part 1.1 Analysis of the thymus 7 Part 1.2 Analysis of a lymph node 7 Part 1.3 Analysis of the spleen 7 Part 2 Questions on the Lymphatic System 9 Total 30 *All due dates can be found on your Canvas calendar or the Modules section. References 1. Saladin, K. (2019). Anatomy and Physiology: The Unity of Form and Function (9 th ed.). McGrawHill Materials 1. Microscope 2. Slides of: a. Lymph node – You will need to use an image from online to complete this as we do not have slides in the classroom of a lymph node. b. Thymus c. Spleen 3. Relevant models PART 1: Histologic analysis of immune system tissues 1. Using your microscope, take (using a tablet or your mobile phone) or draw pictures of the lymph node, thymus, and spleen. Label and describe the function of the indicated structures in each organ. It is easiest to do this in PowerPoint using images, arrows, and text boxes, but you may also submit a Word document if preferred. Descriptions should be written in sentence form, no longer than a paragraph, and may only need 1-2 sentences to be complete. 1.1. Lymph node (7 pts) 1.1.1. Lymphatic cortex (with B cells) 1.1.2. Germinal Center 1.1.3. Lymphatic medulla 1.1.4. Lymphatic sinus 1.1.5. Connective tissue capsule 1.2. Thymus (7 pts) 1.2.1. Cortex 1.2.2. Medulla 1.2.3. T lymphocytes 1.2.4. Thymic corpuscles 1.3. Spleen (7 pts) 1.3.1. White pulp 1.3.2. Red pulp 1.3.3. Trabecula 1.3.4. Capsule 1.3.5. Central artery 1.4. Submit a Word or PowerPoint document with the above images, labels, and descriptions to Week 4: Lymphatic System Structure and Function (Onsite Lab 4 of 7).

BIOS 255 – Week 4 Lab Instructions PART 2: Histologic analysis of immune system tissues Answer the following questions completely and thoroughly. 1. Describe the flow of lymph starting at the capillaries and ending at the cardiovascular system. Include ALL of the structures in which it passes through (i.e. what structures does it pass through within the lymph nodes). Starting at the lymphatic capillaries, fluid accumulates in the interstitial space inside tissues. These lymph capillaries then feed into larger lymph vessels. The collecting vessels usually transport lymph fluid into lymph nodes or lymph trunks. The sinuses converge at the hilium of the node where the lymph leaves the node through an efferent lymphatic vessel toward a central lymph node or a lymph duct for drainage into one of the subclavian veins.

2. It has been found that an individual has metastatic cancerous cells within lymph nodes above the right subclavian vein but NOT above the left subclavian vein. What can you narrow down in regards to its original site of production? How did it get there (i.e. discuss a hypothetical pathway it must have taken).

From the information given, you can assume that the original site of production came from the right side of the body. Reason for this, is because it is only showing up in the lymph nodes prior to moving to the right subclavian vein. It would have been harder to tell where it came from if it had originally came from the left side because it can be anywhere.

3. Describe the process of Bulk filtration (you may use diagrams) and how it relates to the lymphatic system. Bulk flow is used by lipd-insoluble solutes in water to cross the capillary wall. The three kinds of capillaries are continuous capillaries which have a tight space to reduce bulk flow. Fenestrated capillaries which allow a larger amount of flow, and discontinuous capillaries that allow the largest amount of flow to pass. Bulk flow filtration relates to the lymphatic system, because in a way it is deciding what does and does not get passed the capillary wall. The immune system’s job is to protect the body from any invaders that will cause the body harm....