Ch22 - Lecture notes ch 22 PDF

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Package Title: Testbank Course Title: pap13 Chapter Number: 22

Question type: Multiple Choice

1) Which of the following is NOT a function of the lymphatic and immune system? a) Draining excess interstitial fluid b) Maintaining water homeostasis in the body c) Transporting dietary lipids d) Carrying out immune responses Answer: b Difficulty: Easy Learning Objective 1: 22.1 Understand the various components and major functions of the lymphatic system. Learning Objective 2: 22.1.1 List the components and major functions of the lymphatic system. Section Reference 1: 22.1 Lymphatic System Structure and Function

2) What is the major difference between lymph and interstitial fluid? a) Composition of electrolytes b) White blood cells are present in lymph c) Location d) Types of proteins present e) Red blood cells are present in interstitial fluid Answer: c Difficulty: Easy Learning Objective 1: 22.1 Understand the various components and major functions of the lymphatic system. Learning Objective 2: 22.1.3 Explain the formation and flow of lymph. Section Reference 1: 22.1 Lymphatic System Structure and Function

3) Lack of resistance is also known as: a) Pathogenic b) Innate c) Specific

d) Susceptibility e) Lymphatic Answer: d Difficulty: Easy Learning Objective 1: 22.1 Understand the various components and major functions of the lymphatic system. Learning Objective 2: 22.1.1 List the components and major functions of the lymphatic system. Section Reference 1: Chapter Opener

Question type: Essay

4) Describe how lymphatic capillaries are one-way only vessels. Answer: Difficulty: Medium Learning Objective 1: 22.1 Understand the various components and major functions of the lymphatic system. Learning Objective 2: 22.1.2 Describe the organization of lymphatic vessels. Section Reference 1: 22.1 Lymphatic System Structure and Function Solution: The ends of the endothelial cells in the wall of the lymphatic capillary overlap. When pressure is higher in the interstitial fluid than in the lymph, the cells separate slightly allowing interstitial fluid into the vessel. When pressure is greater inside, the cells are tightly packed, not allowing the lymph to cross back into the interstitial fluid.

Question type: Multiple Choice

5) What causes lymph from the small intestines to appear white? a) Proteins b) WBC c) RBC d) Lipids e) Carbohydrates Answer: d Difficulty: Medium Learning Objective 1: 22.1 Understand the various components and major functions of the lymphatic system.

Learning Objective 2: 22.1.1 List the components and major functions of the lymphatic system. Section Reference 1: 22.1 Lymphatic System Structure and Function

6) Which of the following is not considered an organ of the immune system? a) Spleen b) Lymph node c) Red bone marrow d) Thymus e) Pancreas Answer: e Difficulty: Easy Learning Objective 1: 22.1 Understand the various components and major functions of the lymphatic system. Learning Objective 2: 22.1.4 Compare the structure and functions of the primary and secondary lymphatic organs and tissues. Section Reference 1: 22.1 Lymphatic System Structure and Function

7) The left subclavian vein receives lymph from a) Left axillary vein b) Lumbar trunk c) Jugular trunk d) Thoracic duct e) Right lymphatic duct Answer: d Difficulty: Medium Learning Objective 1: 22.1 Understand the various components and major functions of the lymphatic system. Learning Objective 2: 22.1.2 Describe the organization of lymphatic vessels. Section Reference 1: 22.1 Lymphatic System Structure and Function

8) The lymph from the right foot empties into the a) Left axillary vein b) Lumbar trunk c) Jugular trunk d) Thoracic duct e) Right lymphatic duct

Answer: d Difficulty: Medium Learning Objective 1: 22.1 Understand the various components and major functions of the lymphatic system. Learning Objective 2: 22.1.2 Describe the organization of lymphatic vessels. Section Reference 1: 22.1 Lymphatic System Structure and Function

9) The skeletal muscle and respiratory pumps are used in a) Lymphatic system b) Cardiovascular system c) Immune system d) Lymphatic and Immune systems only e) Lymphatic, Immune and Cardiovascular systems Answer: e Difficulty: Medium Learning Objective 1: 22.1 Understand the various components and major functions of the lymphatic system. Learning Objective 2: 22.1.3 Explain the formation and flow of lymph. Section Reference 1: 22.1 Lymphatic System Structure and Function

10) Which organ produces a hormone that promotes maturation of T cells? a) Spleen b) Lymph node c) Red bone marrow d) Thymus e) Pancreas Answer: d Difficulty: Easy Learning Objective 1: 22.1 Understand the various components and major functions of the lymphatic system. Learning Objective 2: 22.1.4 Compare the structure and functions of the primary and secondary lymphatic organs and tissues. Section Reference 1: 22.1 Lymphatic System Structure and Function

11) In which part of the thymus are T cells thought to die?

a) Capsule b) Trabeculae c) Epithelial cells d) Hassall’s corpuscles e) T cells do not die in the thymus Answer: d Difficulty: Medium Learning Objective 1: 22.1 Understand the various components and major functions of the lymphatic system. Learning Objective 2: 22.1.4 Compare the structure and functions of the primary and secondary lymphatic organs and tissues. Section Reference 1: 22.1 Lymphatic System Structure and Function

12) Which portion of the lymph node does not contain any lymphatic nodules. a) Inner cortex b) Outer cortex Answer: a Difficulty: Medium Learning Objective 1: 22.1 Understand the various components and major functions of the lymphatic system. Learning Objective 2: 22.1.4 Compare the structure and functions of the primary and secondary lymphatic organs and tissues. Section Reference 1: 22.1 Lymphatic System Structure and Function

13) Which of the following is a function of the spleen? a) Removes worn out blood cells b) Circulates lymph c) Cleanses interstitial fluid d) Cleanses lymph e) Traps microbes with mucus Answer: a Difficulty: Medium Learning Objective 1: 22.1 Understand the various components and major functions of the lymphatic system.

Learning Objective 2: 22.1.4 Compare the structure and functions of the primary and secondary lymphatic organs and tissues. Section Reference 1: 22.1 Lymphatic System Structure and Function

14) Which of these does NOT provide a physical or chemical barrier? a) Macrophages b) Saliva c) Urine d) Mucus e) Stratified squamous epithelium Answer: a Difficulty: Easy Learning Objective 1: 22.3 Describe the components of innate immunity. Section Reference 1: 22.3 Innate Immunity

Question type: Essay

15) Describe the barriers used in innate defense. Answer: Difficulty: Medium Learning Objective 1: 22.3 Describe the components of innate immunity. Section Reference 1: 22.3 Innate Immunity Solution: Barriers used by the innate defense include epidermis, mucus, hairs, cilia, lacrimal apparatus, saliva, urine, vaginal secretions, sebum, perspiration and gastric juices.

Question type: Multiple Choice

16) Which of these provides a non-specific cellular disease resistance mechanism? a) Macrophages b) T lymphocytes c) B lymphocytes d) Memory B cells e) Stratified squamous epithelium Answer: a

Difficulty: Easy Learning Objective 1: 22.3 Describe the components of innate immunity. Section Reference 1: 22.3 Innate Immunity

17) Which anti-microbial substances reduce viral replication (in uninfected cells)? a) Transferrins b) Perforins c) Complement proteins d) Defensins e) Interferons Answer: e Difficulty: Medium Learning Objective 1: 22.3 Describe the components of innate immunity. Section Reference 1: 22.3 Innate Immunity

18) Which anti-microbial substances promote cytolysis, phagocytosis and inflammation? a) Transferrins b) Perforins c) Complement proteins d) Defensins e) Interferons Answer: c Difficulty: Medium Learning Objective 1: 22.3 Describe the components of innate immunity. Section Reference 1: 22.3 Innate Immunity

19) Which cell kills infected body cells and tumor cells? a) Natural killer cells b) Perforins c) platelets d) Mucus e) Antimicrobial proteins Answer: a

Difficulty: Easy Learning Objective 1: 22.3 Describe the components of innate immunity. Section Reference 1: 22.3 Innate Immunity

20) Which of the following is NOT a sign of inflammation? a) Redness b) Pain c) Heat d) Mucus production e) Swelling Answer: d Difficulty: Easy Learning Objective 1: 22.3 Describe the components of innate immunity. Section Reference 1: 22.3 Innate Immunity

21) Which of the following intensifies the effect of interferons and promotes the rate of repair? a) Complement proteins b) Perforin c) Fever d) Macrophages e) Natural killer cells Answer: c Difficulty: Easy Learning Objective 1: 22.3 Describe the components of innate immunity. Section Reference 1: 22.3 Innate Immunity

22) Which does NOT induce vasodilation and permeability (increased fluid flow) to an infection site? a) Histamines b) Kinins c) Perforin d) Leukotrienes e) Complement Answer: c

Difficulty: Medium Learning Objective 1: 22.3 Describe the components of innate immunity. Section Reference 1: 22.3 Innate Immunity

23) When B and T cells are fully developed and mature, they are described as being a) Immunocompetent b) Pluripotent stem cells c) Primary lymphatic cells d) Specifically promoted e) Germ cells Answer: a Difficulty: Easy Learning Objective 1: 22.4 Understand the components and functions of adaptive (specific) immunity and compare cell-mediated and antibody-mediated immunity. Learning Objective 2: 22.4.1 Define adaptive immunity, and describe how T cells and B cells arise. Section Reference 1: 22.4 Adaptive Immunity

24) Which induces the production of a specific antibody? a) Phagocytosis b) Antigen c) Antibody d) Defensin e) Immunoglobulin Answer: b Difficulty: Easy Learning Objective 1: 22.4 Understand the components and functions of adaptive (specific) immunity and compare cell-mediated and antibody-mediated immunity. Learning Objective 2: 22.4.2 Explain the relationship between an antigen and an antibody. Section Reference 1: 22.4 Adaptive Immunity

25) Which stimulates an immune response ONLY when it is attached to a large carrier molecule? a) Epitope b) Antigen c) Hapten d) MHC antigen

e) CD8 Answer: c Difficulty: Easy Learning Objective 1: 22.4 Understand the components and functions of adaptive (specific) immunity and compare cell-mediated and antibody-mediated immunity. Learning Objective 2: 22.4.2 Explain the relationship between an antigen and an antibody. Section Reference 1: 22.4 Adaptive Immunity

26) Genetic recombination generates diversity in what part (s) of the immune system? a) Antigen receptors b) MHC antigen c) Hapten d) MHC antigen and antigen receptors e) Epitopes Answer: d Difficulty: Medium Learning Objective 1: 22.4 Understand the components and functions of adaptive (specific) immunity and compare cell-mediated and antibody-mediated immunity. Learning Objective 2: 22.4.2 Explain the relationship between an antigen and an antibody. Section Reference 1: 22.4 Adaptive Immunity

27) Which class of cells includes macrophages, B cells and dendritic cells? a) Antigen presenting cells b) Primary lymphocytes c) T cells d) RBC e) Epitope cells Answer: a Difficulty: Medium Learning Objective 1: 22.4 Understand the components and functions of adaptive (specific) immunity and compare cell-mediated and antibody-mediated immunity. Learning Objective 2: 22.4.2 Explain the relationship between an antigen and an antibody. Section Reference 1: 22.4 Adaptive Immunity

28) To become activated, which requires being bound to a foreign antigen AND simultaneous costimulation? a) B Cell b) T Cell c) Interferon d) MHC antigen e) Antigen presenting cell Answer: b Difficulty: Hard Learning Objective 1: 22.5 Understand the components and functions of the cell-mediated immune response. Learning Objective 2: 22.5.1 Outline the steps in a cell-mediated immune response. Section Reference 1: 22.5 Cell-mediated Immunity

29) Which cells display CD4 proteins and interact with MHC Class II antigens? a) Cytotoxic T cells b) Helper T Cells c) Memory T Cells d) MHC antigens e) B cells Answer: b Difficulty: Medium Learning Objective 1: 22.5 Understand the components and functions of the cell-mediated immune response. Learning Objective 2: 22.5.1 Outline the steps in a cell-mediated immune response. Section Reference 1: 22.5 Cell-mediated Immunity

30) Which T cell toxin fragments DNA? a) Perforin b) Tumor antigen c) Interferons d) Lymphotoxin e) Toxin T Answer: d Difficulty: Medium

Learning Objective 1: 22.5 Understand the components and functions of the cell-mediated immune response. Learning Objective 2: 22.5.1 Outline the steps in a cell-mediated immune response. Section Reference 1: 22.5 Cell-mediated Immunity

Question type: Essay

31) List the five actions of antibodies. Answer: Difficulty: Medium Learning Objective 1: 22.6 Understand the components and functions of the antibody-mediated immune response. Learning Objective 2: 22.6.2 List the chemical characteristics and actions of antibodies. Section Reference 1: 22.6 Antibody-mediated Immunity Solution: Antibodies can act as a neutralizing agent, they can immobilize bacteria, agglutinate and precipitate the antigen, activate the complement and enhance phagocytosis.

Question type: Multiple Choice

32) Which class of antibodies is mainly found in sweat, tears, breast milk and GI secretions? a) IgG b) IgA c) IgM d) IgD e) IgE Answer: b Difficulty: Medium Learning Objective 1: 22.6 Understand the components and functions of the antibody-mediated immune response. Learning Objective 2: 22.6.2 List the chemical characteristics and actions of antibodies. Section Reference 1: 22.6 Antibody-mediated Immunity

33) Which leads to inflammation, enhancement of phagocytosis and lysis of microbes? a) Classical complement system b) Alternative complement system

c) Apoptosis d) Classical and Alternative complement systems e) Hapten activation Answer: d Difficulty: Medium Learning Objective 1: 22.6 Understand the components and functions of the antibody-mediated immune response. Learning Objective 2: 22.6.3 Explain how the complement system operates. Section Reference 1: 22.6 Antibody-mediated Immunity

34) Which action makes microbes more susceptible to phagocytosis? a) Opsonization b) Cytolysis c) Inflammation d) Complement e) Hybridoma Answer: a Difficulty: Easy Learning Objective 1: 22.6 Understand the components and functions of the antibody-mediated immune response. Learning Objective 2: 22.6.3 Explain how the complement system operates. Section Reference 1: 22.6 Antibody-mediated Immunity

35) Which is an inactive, self responsive cell? a) Deleted cell b) Hybridoma cell c) Epitopic cell d) Anergy cell e) Natural killer cell Answer: d Difficulty: Medium Learning Objective 1: 22.7 Describe how self-recognition and self-tolerance develop. Section Reference 1: 22.7 Self-Recognition and Self-Tolerance

36) In the diagram, where do pluripotent stem cells come from?

a) A b) B c) C d) D e) None of these choices Answer: b Difficulty: Medium Learning Objective 1: 22.1 Understand the various components and major functions of the lymphatic system. Learning Objective 2: 22.1.1 List the components and major functions of the lymphatic system. Section Reference 1: 22.1 Lymphatic System Structure and Function

37) In the diagram, where do T cells mature?

a) A b) B c) C d) D e) None of these choices Answer: a Difficulty: Easy Learning Objective 1: 22.1 Understand the various components and major functions of the lymphatic system. Learning Objective 2: 22.1.4 Compare the structure and functions of the primary and secondary lymphatic organs and tissues. Section Reference 1: 22.1 Lymphatic System Structure and Function

38) In the diagram, what is comprised of white and red pulp?

a) A b) B c) C d) D e) None of these choices Answer: c Difficulty: Medium Learning Objective 1: 22.1 Understand the various components and major functions of the lymphatic system. Learning Objective 2: 22.1.4 Compare the structure and functions of the primary and secondary lymphatic organs and tissues. Section Reference 1: 22.1 Lymphatic System Structure and Function

Question type: Essay

39) What does this diagram represent?

Answer: Difficulty: Easy Learning Objective 1: 22.1 Understand the various components and major functions of the lymphatic system. Learning Objective 2: 22.1.2 Describe the organization of lymphatic vessels. Section Reference 1: 22.1 Lymphatic System Structure and Function Solution: The one-way flow of lymph through a lymph vessel.

Question type: Multiple Choice

40) In the diagram this vessel drains lymph from the upper right side of the body into venous blood using a subclavian vein.

a) B b) C c) F d) G e) E Answer: b Difficulty: Medium Learning Objective 1: 22.1 Understand the various components and major functions of the lymphatic system. Learning Objective 2: 22.1.2 Describe the organization of lymphatic vessels. Section Reference 1: 22.1 Lymphatic System Structure and Function

41) In the diagram these are the bronchomediastinal trunks.

a) A and F b) B and G c) C and H d) D and I e) E and J Answer: d Difficulty: Medium Learning Objective 1: 22.1 Understand the various components and major functions of the lymphatic system. Learning Objective 2: 22.1.2 Describe the organization of lymphatic vessels. Section Reference 1: 22.1 Lymphatic System Structure and Function

42) In the diagram, which consists of a medulla, medullary sinus and reticular fibers?

a) B b) C c) D d) E e) F Answer: c Difficulty: Medium Learning Objective 1: 22.1 Understand the various components and major functions of the lymphatic system. Learning Objective 2: 22.1.4 Compare the structure and functions of the primary and secondary lymphatic organs and tissues. Section Reference 1: 22.1 Lymphatic System Structure and Function

43) Which region includes B cells, follicular dendritic cells and macrophages?

a) B b) C c) D d) E e) F Answer: b Difficulty: Medium Learning Objective 1: 22.1 Understand the various components and major functions of the lymphatic system. Learning Objective 2: 22.1.4 Compare the structure and functions of the primary and secondary lymphatic organs and tissues. Section Reference 1: 22.1 Lymphatic System Structure and Function

44) In the diagram, which region includes B cells, plasma cells and macrophages?

a) B b) C c) D d) E e) None of these choices Answer: c Difficulty: Medium Learning Objective 1: 22.1 Understand the various components and major functions of the lymphatic system. Learning Objective 2: 22.1.4 Compare the structure and functions of the primary and secondary lymphatic organs and tissues. Section Reference 1: 22.1 Lymphatic System Structure and Function

Question type: Essay

45) Describe what is happening in the diagram.

Answer: Difficulty: Easy Learning Objective 1: 22.4 Understand the components and functions of adaptive (specific) immunity and compare cell-mediated and antibody-mediated immunity. Learning Objective 2: 22.4.3 Compare the functions of cell-mediated immunity and antibodymediated immunity. Section Reference 1: 22.4 Adaptive Immunity Solution: The diagram represents processing and presenting of exogenous antigen by an antigenpresenting cell.

Question type: Multiple Choice

46) The inability of the immune system to protect the body from a pathogen causes a) immunodeficiency diseases b) alle...