HUBS2505 Course Outline PDF

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Description

Faculty of Health and Medicine

School of Biomedical Sciences and Pharmacy HUBS2505: Human Pathophysiology Callaghan Semester 1 - 2020

OVERVIEW Course Description

This course provides an introduction to the concept of human disease and the pathophysiological mechanisms underlying the causes. Students will be provided with an introduction to pathophysiology of the immune, endocrine, circulatory, respiratory, gastrointestinal, musculoskeletal, renal and nervous systems. Associated pathologies of these systems will be introduced and explored.

Assumed Knowledge

HUBS1403 Biomedical Sciences Part 1 HUBS1404 Biomedical Science Part 2

Contact Hours

Callaghan Lecture Face to Face On Campus 3 hour(s) per Week for 12 Weeks Tutorial Face to Face On Campus 1 hour(s) per Week for 12 Weeks Mid semester examinations will be timetabled during the week

Unit Weighting

10

Workload

Students are required to spend on average 120-140 hours of effort (contact and non-contact) including assessments per 10 unit course.

CONTACTS Course Coordinator

All Locations Dr Michael Bourke

[email protected] Consultation: Available by appointment Teaching Staff

Dr Michael Bourke Contact e-mail: [email protected] Dr Elham Sadeqzadeh Contact e-mail: [email protected]

School Office

School of Biomedical Sciences and Pharmacy MS607 Medical Sciences Building Callaghan [email protected] 02 49218679 or 49212058 8:30am-5pm (Mon-Fri) CRICOS Provider 00109J

HUBS2505: Human Pathophysiology Callaghan Semester 1 - 2020

SYLLABUS Course Content

Students will initially be introduced to the concepts of disease, some basic terminology of pathophysiology and to the mechanisms by which cells undergo injury and adapt to such insult. This will be followed by a module comprising an overview of infection and immune responses to pathogenic agents, inflammation, and hypersensitivity, autoimmunity and immunodeficiency. Common endocrine disorders will also be discussed. The second module will consider pathophysiological mechanisms underlying disorders of blood and the lymphatic system together with an introduction to mechanisms underlying neoplasms. Module three explores cardiovascular disease and includes consideration of the consequences of structural abnormalities, disorders of electro-conduction, ischaemic heart disease, heart failure and common vascular disorders. Module four involves the respiratory system and will focus on acute pulmonary syndromes, obstructive and restrictive disease. Module five will discuss upper and lower gastrointestinal tract pathophysiology, and will also examine disorders of the accessory organs of the digestive system – liver, pancreas and gall bladder. Module six considers pathophysiological mechanisms underlying disorders of the musculoskeletal system. Renal pathophysiology including aspects of acute and chronic renal failure and some common diseases that affect kidney function will also be considered in this module. Module seven will explore the mechanisms underlying pathophysiology of neurological dysfunction; at both the cellular and systems level as occurs in stroke, space occupying lesions, degenerative disorders and with injury to peripheral and central elements of the nervous system.

Course Learning Outcomes

Course Materials

1. Develop an understanding of the concept of human disease. 2. Develop an understanding of the pathology and pathophysiology associated with disorders of the immune, endocrine, circulatory, respiratory, gastrointestinal, musculoskeletal, renal and nervous systems. 3. Develop an understanding of the pathophysiological mechanisms and processes underlying human diseases.

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Recommended Text: Gould’s Pathophysiology for Health Professions, 6th Edition (2017), Hubert & VanMeter, Elsevier. ISBN 9780323414425 Study guide for Gould’s Pathophysiology for Health Professions, 6th Edition (2017), Hubert & VanMeter, Elsevier.

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HUBS2505: Human Pathophysiology Callaghan Semester 1 - 2020

COMPULSORY REQUIREMENTS In order to pass this course, each student must complete ALL of the following compulsory requirements:

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Course Assessment Requirements: Assessment 1 - In Term Test: Attempt / Submission Requirement - Students must attempt/submit this assessment item to be able to pass the course overall. Assessment 2 - Formal Examination: Attempt / Submission Requirement - Students must attempt/submit this assessment item to be able to pass the course overall.

ASSESSMENTS This course has 2 assessments. Each assessment is described in more detail in the sections below. Assessment Name 1 2

Intra-semester exams (x2)* Final exam*

Due Date Week 5 Wed 8-9am Week 9 Wed 8-9am

Involvement

Weighting

Individual

50%

Individual

50%

Learning Outcomes 1-3 1-3

* This assessment has a compulsory requirement.

Assessment 1 - Intra-semester exams (x2) Assessment Type Weighting Compulsory Requirements Due Date Submission Method Assessment Criteria

In Term Test 25% each Attempt / Submission Requirement - Students must attempt/submit this assessment item to be able to pass the course overall. Week 5 Wed 8-9am 25th March HD01 Week 9 Wed 8-9am 6th May HD01 In class These are CLOSED BOOK examinations and no notes are allowed. All assessment items will consist of Multiple Choice Questions (MCQs) with one best correct option Mini-test 1: Week 5 Wed 8-9am 25th March HD01 This test will assess the material covered during Weeks 1-3, specifically: Concepts of disease Cell injury Infection Inflammation & healing Immunity & abnormal immune responses Endocrine disorders Blood dyscrasias Leukaemia & lymphatic disorders Neoplasms Mini-test 2: Week 9 Wed 8-9am 6th May HD01 This test will assess the material covered during Weeks 4-7, specifically: Structural abnormalities of the heart Electrical abnormalities of the heart Congestive heart failure Atherosclerosis & arterial disease Ischaemic heart disease & CAD Shock/Hypotension Respiratory tract infections Obstructive lung disorders I & II Restrictive & vascular lung disorders Respiratory expansion disorders, distress syndrome & failure Page 3 of 7

HUBS2505: Human Pathophysiology Callaghan Semester 1 - 2020

Assessment Criteria Return Method Feedback Provided

Further details, will be placed on the Course Blackboard site prior to each of these assessments Not Returned Yes

Assessment 2 - Final exam Assessment Type Weighting Compulsory Requirement Due Date Submission Method Assessment Criteria Return Method Feedback Provided

Formal Examination 50% Attempt / Submission Requirement - Students must attempt/submit this assessment item to pass the course overall. Formal Exam period Formal Exam conditions This is a CLOSED BOOK examination and no notes are allowed. All assessment items will consist of Multiple Choice Questions (MCQs) with one best correct option Not Returned No

ADDITIONAL INFORMATION Grading Scheme

This course is graded as follows: Range of Grade Description Marks 85-100 High Outstanding standard indicating comprehensive Distinction knowledge and understanding of the relevant (HD) materials; demonstration of an outstanding level of academic ability; mastery of skills*; and achievement of all assessment objectives. 75-84 Distinction Excellent standard indicating a very high level of (D) knowledge and understanding of the relevant materials; demonstration of a very high level of academic ability; sound development of skills*; and achievement of all assessment objectives. 65-74 Credit Very Good standard indicating a high level of (C) knowledge and understanding of the relevant materials; demonstration of a high level of academic ability; reasonable development of skills*; and achievement of all assessment objectives. 50-64 Pass Satisfactory standard indicating an adequate (P) knowledge and understanding of the relevant materials; demonstration of an adequate level of academic ability; satisfactory development of skills*; and achievement of most assessment objectives. 0-49 Fail Failure to satisfactorily achieve assessment (FF) objectives or compulsory course requirements. A fail grade may also be awarded following disciplinary action.

Communication Methods

Communication methods used in this course include: - Blackboard Course Site: Students will receive communications via the posting of content or announcements on the Blackboard course site. - Email: Students will receive communications via their student email account.

Course Evaluation

Each year feedback is sought from students and other stakeholders about the courses offered in the University for the purposes of identifying areas of excellence and potential improvement.

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HUBS2505: Human Pathophysiology Callaghan Semester 1 - 2020

Academic Misconduct

All students are required to meet the academic integrity standards of the University. These standards reinforce the importance of integrity and honesty in an academic environment. Academic Integrity policies apply to all students of the University in all modes of study and in all locations. For the Student Academic Integrity Policy, refer to https://policies.newcastle.edu.au/document/view-current.php?id=35.

Adverse Circumstances

You are entitled to apply for special consideration because adverse circumstances have had an impact on your performance in an assessment item. This includes applying for an extension of time to complete an assessment item. Prior to applying you must refer to the Adverse Circumstances Affecting Assessment Items Procedure, available at https://policies.newcastle.edu.au/document/view-current.php?id=236. All applications for Adverse Circumstances must be lodged via the online Adverse Circumstances system, along with supporting documentation.

Important Policy Information

The 'HELP for Students' tab in UoNline contains important information that all students should be familiar with, including various systems, policies and procedures.

Tutorial Group Week 2-6, 8-12 (weeks 1 & 7 no tutorial)

Tut Group

Day

Time

Venue

Gp 1 Gp 2

Thu Thu

10-11am 2-3pm

STHG01 GP201

See lecture timetable next page

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HUBS2505 HUMAN PATHOPHYSIOLOGY LECTURE AND TUTORIAL SCHEDULE Course Location CALLAGHAN

Week WK 1

WK 2

WK 3

WK 4

WK 5

WK 6

WK 7

Duration (hrs)

Date

Teaching Staff

25 Feb 26 Feb 27 Feb

Sadeqzadeh Sadeqzadeh Sadeqzadeh

Tue Wed Thu

4pm 12pm 5pm

1 1 1 Nil

Lecture Lecture Lecture

RW149 RW149 RW149

3 Mar 4 Mar 5 Mar

Sadeqzadeh Sadeqzadeh Sadeqzadeh

Tue Wed Thu

4pm 12pm 5pm

1 1 1

Lecture Lecture Lecture

RW149 RW149 RW149

1

Tutorial Lecture Lecture Lecture

Day

Time

10 Mar 11 Mar

Sadeqzadeh Sadeqzadeh

Tue Wed

4pm 12pm

1 1

12 Mar

Sadeqzadeh

Thu

5pm

1 1

Format

Topic

Location

RW149 RW149 RW149

Tutorial

Inflammation, immunity and endocrine disorders

Lecture Lecture

Structural abnormalities of the heart

RW149

Lecture Tutorial

Electrical abnormalities of the heart Congestive heart failure Blood, lymph, and neoplasm

RW149 RW149

RW149 HD01 RW149 RW149

17 Mar

Sadeqzadeh

Tue

4pm

1

18 Mar 19 Mar

Sadeqzadeh Sadeqzadeh

Wed Thu

12pm 5pm

1 1 1

24 Mar 25 Mar 25 Mar 26 Mar

Sadeqzadeh Sadeqzadeh Sadeqzadeh Sadeqzadeh

Tue Wed Wed Thu

4pm 8am 12pm 5pm

1 1 1 1

Lecture

Atherosclerosis & arterial disease

TEST 1 Lecture Lecture

Ischaemic heart disease & CAD Shock/Hypotension

1

Tutorial

Heart dysfunction

Lecture Lecture Lecture

Respiratory tract infections Obstructive lung disorders I

RW149 RW149

Obstructive lung disorders II Vascular dysfunction

RW149

Restrictive & vascular lung disorders Respiratory expansion disorders, distress syndrome & failure Interactive session and MT1 feedback

RW149

31 Mar 01 Apr

Sadeqzadeh Sadeqzadeh

Tue Wed

4pm 12pm

1 1

02 Apr

Sadeqzadeh

Thu

5pm

1 1

Tutorial

07 Apr

Sadeqzadeh

Tue

4pm

1

Lecture

08 Apr 09 Apr

Sadeqzadeh Sadeqzadeh

Wed Thu

12pm 5pm

1 1

Lecture Lecture

RW149 RW149

No tutorial

Nil

HUBS2505: Human Pathophysiology Callaghan Semester 1 - 2020 Course Location CALLAGHAN

Week WK 8

WK 9

WK 10

WK 11

WK 12

Date

Teaching Staff

Day

Time

Duration (hrs)

28 Apr 29 Apr 30 Apr

Sadeqzadeh Sadeqzadeh Sadeqzadeh

Tue Wed Thu

4pm 12pm 5pm

1 1 1 1

05 May 06 May 06 May

Sadeqzadeh Sadeqzadeh Sadeqzadeh

Tue Wed Wed

4pm 8am 12pm

1 1 1

07 May

Sadeqzadeh

Thu

5pm

1 1

Format Lecture Lecture Lecture Tutorial Lecture TEST 2 Lecture Lecture Tutorial Lecture Lecture

Topic

Location

Gastrointestinal tract disorders I Gastrointestinal tract disorders II Liver & pancreatic disorders Respiratory dysfunction

RW149 RW149 RW149

Musculoskeletal disorders I

RW149 HD01 RW149

Musculoskeletal disorders II Diabetes Gastrointestinal tract and liver disorders

RW149

Urinary infections & inflammation

RW149

Urinary tract obstructions & vascular disorders Renal failure Musculoskeletal disorders and diabetes

RW149 RW149

12 May

Sadeqzadeh

Tue

4pm

1

13 May 14 May

TBA Sadeqzadeh

Wed Thu

12pm 5pm

1 1 1

19 May 20 May 21 May

Sadeqzadeh TBA Sadeqzadeh

Tue Wed Thu

4pm 12pm 5pm

1 1 1 1

Lecture Lecture Lecture Tutorial

Acute neurological disorders Stroke Dysfunctional pain Renal dysfunction

RW149 RW149 RW149

26 May 27 May 28 May

Sadeqzadeh TBA Sadeqzadeh

Tue Wed Thu

4pm 12pm 5pm

1 1 1

Lecture Lecture Lecture

Chronic CNS disorders Dementia Disorders of thought & mood

RW149 RW149 RW149

1

Tutorial

Neurological dysfunction

Lecture Tutorial

Exam Period June 9th - June 20th Rescheduled exam period July 13th –July 17th *Please note that all students are expected to be available during BOTH formal and rescheduled exam periods. In the event that you have an approved rescheduled exam, this will be held in the rescheduled exam period. If you have made plans to travel or work during that period, you will not be offered another opportunity to sit the examination. This course outline was approved by the Head of School. No alteration of this course outline is permitted without Head of School approval. If a change is approved, students will be notified and an amended course outline will be provided in the same manner as the original. © 2020 The University of Newcastle, Australia

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