Ibutilide PDF

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Summary

Ibutilide...

Description

Class: Class

III antidysrhythmic drug

Generic Drug Name: Ibutilide

(Corvert)

Method of Action (MOA): Activates slow inward current of sodium in cardiac tissue, resulting in delayed repolarization, prolonged action potential duration, and increased refractoriness. Mildly slows sinus rate and AV conduction.

Indications/Uses and expected Therapeutic outcome - indicated for atrial dysrhythmias. AF and atrial flutter (AFL). Only drugs available for rapid conversion of these two conditions (AF & AFL) to normal sinus rhythm. - Therapeutic effect: Conversion to normal sinus rhythm. Contraindications and Precautions-

Hypersensitivity HF or left ventricular dysfunction (^ risk for more serious arrhythmias during infusion) Pregnancy & children 60kg, then 0.1 mg/kg) Education or teaching – Inform patient of the purpose of ibutilide. Evaluation - Evaluate for Conversion of recent-onset atrial flutter or fibrillation to normal sinus rhythm....