Industrial Internship Report PDF

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Summary

This is an industry internship that is mandatory for pharmacy students....

Description

8th Sem B. Pharm

2020-21

1. INTRODUCTION

ABOUT AROGYA JYOTI

AROGYA JYOTI PHARMACY is founded in 1994, now the fastest growing Ayurveda company. The company is a leading provider of high-quality products and service to its customers. The house of AROGYA JYOTI PHARMACY offer hi-tech therapeutics well assured for quality. Arogya Jyoti Pharmacy ethical range of formulations are as per global standard GMP, & as per schedule compliance. It is needless to mention that there is strong need of quality control & standardization for the high-profile herbal healthcare formulations. House of AROGYA JYOTI PHARMACY is strongly committed in this context, to offer well standardized herbal extract/remedies ensured for Authenticity, Purity, and Quality & Proven clinical efficiency.

Vision Built around a desire to being not just the best but a leader in developments, manufacturing & sales of premium personal care & healthcare products. Our focus stays in launching new products to widen the scope of our portfolio and to offer a complete range of customers.

Location 59, V P Road, Vithal Udyognagar, GIDC, Vithal Udyognagar, Anand, 388121 Gujarat. Email- [email protected],www.arogyatipharmacy.com

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2. SCHEMATIC LAYOUT OF INDUSTRY

Fig. 1. Schematic Layout of Industry

Industry include different department like … 1. Personnel and administration 2. Raw material department 3. Production(manufacturing) 4. Quality control lab 5. Quality assurance 6. Packaging 7. Store

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3. PERSONNEL AND ADMINISTRATION

Personnel in simple words is a management in which people employed in an organization or engaged in an organized undertaking such as military service. Administration means the process or activity of a business, organization etc. Here I was instructed hoe to behave and how to carry out the work given by the official. The range of clothing available would normally include: •

Hats and hair cover

•

Masks

•

Coveralls- preferably with no pockets or pockets suitably designed to prevent articles falling out

•

Disposal gloves

•

Foot covers and shoes

•

Safety glasses

•

Appropriate clean rooms suits for sterile areas

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4. RAW MATERIAL DEPARTMENT

Raw material storage is a sector of the manufacturing business that is essential to continuous production operations. Raw material storage is something that companies have carefully engineered according to their own unique storage needs to be able to produce a consistent product.

Fig. 2 Raw Material Storage Room

In raw material storage room different types of raw materials like sugar, polymers, herbs, oils, seeds etc. are stored as per requirements of industry. Different boxes and drums are placed in raw material storage room. Before using raw materials for production of medicines there is a checking process of received raw material.

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The below flow chart is followed for checking of raw material.

Fig. 3. Flow Chart For RM/PM Inspection

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5. PRODUCTION (MANUFACTURING)

at Arogya Jyoti Pharmacy different types of medication are manufacturing. They are as follow, ❖ Liquid (drops) ❖ Syrup ❖ Oil ❖ Ointment ❖ Capsules

1) LIQUID (drops)

I.

Digivit- U drops (30 ml) •

Anti-spasmodic

•

Digestive upset

•

Carminative diarrhoea

•

Source of vitamin C

•

Help in digestion of milk

Fig. 4.

II.

U-Ton Drops (30 ml) •

Protect the liver enzyme

•

Used against various toxic of hepatitis

•

Iron liver tonic

Fig. 5.

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2) SYRUP

I.

Balrakshak Syrup (110 ml) •

Help in colic

•

Vomiting and diarrhoea

•

Digestive upset

Fig. 6.

II.

Asmasol Cough Syrup (50 ml & 110 ml) •

Inflammatory catarrhal condition

•

Common cold allergic

•

Spasmodic cough

•

Bronchodilator

• Sore-throated & respiratory tract infection Fig. 7.

III.

Kofjil cough syrup ( 50 ml & 110 ml) •

Allergic and asthmatic cough

•

Acute & bronchitis

• Used in asthma and different types of coughs

Fig. 8.

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2020-21

3) OIL

❖ The picture shows the process of oil filling in bottle, at one time 50 ml oil filled in the bottle, the volume of oil to be filled can be manually. Like 30 ml, 50ml, 100 ml at the time two bottle are filled oil and then go for capping and labelling.

Fig. 9. Oil Filling Machine

I.

Rumajin oil (50 ml & 100 ml) •

Joint pain and inflammation

•

Backache and arthritic disorder

•

Sprains and swelling

•

Anti-rheumatic

Fig. 10.

II.

Rhu Dpain oil (60 ml) •

Joint pain and inflammation

•

Anti-rheumatic

•

Sprains and swelling

Fig.11.

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8th Sem B. Pharm

2020-21

4) OINTMENT

❖ Ointment filing machine have capacity of 20 kg from single batch of the machine nearly 650 ointment tubes are prepared. ❖ Ointment sealing machine seal the tip of ointment tube. At the time two tubes can sealed by the machine.

Fig.12 Ointment Filling & Sealing Machine

I.

Rumajin Ointment (30gm) •

Joint pain and inflammation

•

Backache and arthritic disorder

•

Sprains and swelling

Fig. 13.

II.

Jilpil Ointment (30gm) •

Used in all type of bleeding piles

•

Fissure

•

Haemorrhoids

•

constipation

Fig. 14.

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5) CAPSULES

Instrumentation

Fig.15 Capsule Loader Machine and Filling Machine

•

Capsule filling machine capacity 300 capsule fill in one plate and also have same capacity of loader machine.

•

Capsule size is also important parameter in area. Mostly use size 2” capsule for filling.

Fig.16 Detail Structure of Capsule

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2020-21

5 Steps (30 Capsules) •

Helps in sciatica

•

Joint pain

•

Low back pain

•

Muscle pain

•

Knee joint pain

Fig. 17.

II.

Siddh Dayayog (60 Capsules) •

Non-insulin dependent diabetes mellitus (NIDDM, Type II)

•

Associated symptoms

•

Help to reduce elevated blood glucose level

Fig. 18.

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6. LABORATORY QC ROOM

In the laboratory different analytical instrument are placed for checking the quality of finished products and maintaining the regulation of GMP guidelines.

1. pH meter •

A pH meter is an instrument used to measure acidity or alkalinity of a solution - also known as ph. pH is the unit of measure that describes the degree of acidity or alkalinity. It is measured on a scale of 0 to 14.

Fig.19 pH meter

2. Magnetic Stirrer

•

A magnetic

stirrer or magnetic

mixer is a laboratory device that employs a rotating magnetic field to

cause

a stir bar

(or

flea)

immersed in a liquid to spin very quickly, thus stirring it.

Fig.20 Magnetic Stirrer

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3. Disintegration Apparatus •

Disintegration

Tester is

a

solid-

state instrument designed for the accurate estimation of disintegration time of tablets as per IP/USP standards. The instrument is designed to test two batches of six tablets, simultaneously. The unit is extremely

Fig.21 Disintegration Apparatus

useful for pharmaceutical industries.

4. Oven

•

Laboratory ovens are ovens for highforced

volume

thermal

convection applications. These ovens generally provide uniform temperatures throughout.

Process applications for

laboratory ovens can be for annealing, die-bond

curing,

drying,

Fig.22 Oven

Polyimide baking, sterilizing, and other industrial laboratory functions.

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2020-21

7. Quality Assurance

The Q.A department is a wide-ranging concept covering all matters that individually or collectively influence on the quality of a product. It is concerned with all the in-process quality assurance [IPQA]. Here, I came to know all the basic information about the department in detail. The objective of this department is to provide the best quality material and assure safety. It ensures that the unit performs as per GMP, GLP, and GWP. QA is the heart and soul of quality control. QA = QC + GMP

The Quality Management Mainly focus in: 1. Quality Assurance 2. Quality Checking by GLP 3. GMP 4. GWP 5. GDP 6. Raining & Development 7. Inspection

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2020-21

8. QUALITY CONTROL A system of maintaining standards in manufactured products by testing a sample of the output against the specification.

QC Department has following roles: The quality control is the department which is related with the different parameters of the quality control.

The Q.C department is connected to 5 different departments: 1. Raw material 2. Finished product 3. Stability 4. Packing material 5. Microbiology

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9. Conclusion

Industrial training is very much essential for Pharmacy Students, it is also a great opportunity to acquire practical knowledge. During my training period, in the industry I acquired lots of experiences in Pharmaceutical Production and Production management. I have seen the various instruments and apparatus in the industry and their functions. This will help me to clarify my theoretical knowledge. I hope and pray that it will help me much in

my future profession, during my training period.

❖

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