Lect16 - Lecture 16 PDF

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Lecture 16...

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Lower motoneuron

Principles of Neuroscience

see chapter 16, Purves et al. Peter Kitchener [email protected]

Lecture'plan' ' 1.'''Motoneurons:'the'“final'common'pathway”'' 2.'''The'motor'unit' 3.'''Connections'to'Motoneurons:'peripheral,'segmental'and'supra-spinal' 4.'''More'complex'spinal'circuits:'intersegmental'coordination'&'pattern'generation' 5.'''Features'of'descending'motor'control''

Overall organization of neural structures that control movement

Motoneurons:'the'final'common'pathway'

Adapted from Kandel et al. 2000 Applebaum Press

Spatial distribution of lower motor neurons in the ventral horn of the spinal cord

Somatotopic organization of lower motor neurons

2. The motor unit

Motor endplates (neuromuscular junctions)

Motor neuron recruitment in a cat muscle under different behavioral conditions

3. connections to motoneurons: peripheral, segmental and supra-spinal

Stretch reflex circuitry (Part 1) muscle spindle

Stretch reflex circuitry (Part 2)

Stretch reflex circuitry (Part 3)

The function of muscle spindles and Golgi tendon organs (Part 1)

The function of muscle spindles and Golgi tendon organs (Part 3)

Negative feedback regulation of muscle tension by Golgi tendon organs

4.'More'complex'spinal'circuits:'intersegmental'coordination'and'pattern'generation''

Adapted from Kandel et al. 2000 Applebaum Press

Spinal cord circuitry responsible for the flexion-crossed extension reflex

AO

Central pattern generators in terrestrial mammals (Part 1)

Central pattern generators in terrestrial mammals (Part 2)

Central pattern generators in terrestrial mammals (Part 3)

5.Features of descending motor control

Somatotopic organization of lower motor neurons

1. Supra-spinal (descending) inputs to motoneurons – anatomical considerations

Overview of descending motor control

Descending projections from the brainstem to the spinal cord...