Linezolid PDF

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Linezolid...

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INSTRUCTIONS: 1. For each chapter that teaches about medications, fill in the following table regarding the chosen meds. CLASS: Antiinfective GENERIC NAME: Linezolid MOA: Inhibits bacterial protein synthesis at the level of the 23S ribosome of the 50S subunit.

TRADE NAMES: (Zyvox), (Zyvoxcam)

INDICATIONS: - Infections caused by vancomycin-resistant Enterococcus faecium, -Nosocomial pneumonia caused by Staphylococcus aureus (methicillin-susceptible and -resistant strains), -Complicated skin/skin structure infections caused by Staphylococcus aureus (methicillin-susceptible and -resistant strains), Streptococcus pyogenes or Streptococcus agalactiae (including diabetic foot infections), -Uncomplicated skin/skin structure infections caused by Staphylococcus aureus (methicillin-susceptible and -resistant strains), Streptococcus pyogenes, -Community-acquired pneumonia caused by Streptococcus pneumoniae (including multi-drug resistant strains) or Staphylococcus aureus (methicillinsusceptible strains only). CONTRAINDICATIONS/PRECAUTIONS: Hypersensitivity; Phenylketonuria (suspension contains aspartame); Uncontrolled HTN, pheochromocytoma, thyrotoxicosis, or concurrent use of sympathomimetic agents, vasopressors, or dopaminergic agents (risk of hypertensive response); Concurrent or recent (2 wk of therapy. Discontinue therapy if bone

marrow suppression occurs or worsens. May cause increased AST, ALT, LDH, alkaline phosphatase, and BUN. May cause hypoglycemia requiring decrease in dose of antidiabetic agent or discontinuation of linezolid. SPECIAL CONSIDERATIONS/NOTES: References: Lilley, Rainforth-Collins, Snyder (2020). Pharmacology and the Nursing Process, 9th ed. Elsevier Skidmore-Roth, L. (2019). Mosby's Drug Guide for Nursing SStudents, 13th ed. Elsevier...