Mirtazapine PDF

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Mirtazapine Drug Card...

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Drug Card Template Classification: Tetracyclic antidepressant Generic Name: Mirtazapine

Student Name: Samantha Mendoza

Expected Pharmacological Action: Thought to enhance central noradrenergic and serotonergic activity./ The drug decreases anxiety, agitation, insomnia, and migraine headaches as well as depression. Usual Dose: 15 mg/d PO initially, not to exceed 45 mg/d; usual dosage range 15–45 mg daily Usual routes: PO Therapeutic Uses:

Expected Common Adverse Effects:

1. Used to treat major depressive disorder

1. Drowsiness 2. Weight gain 3. Increased appetite

Adverse Effects Requiring Nursing Action: Adverse Effect Constipation

Aggranulocutyosis or neutropenia

Action: Prevention/Assessment/Intervention Check patient for I&Os; increase fluid intake; ask patient about their last BM. Do a CBC on the patient including a comprehensive WBC count. Assess patient for frequent infections and sickness.

Likely Medication/Food Interactions: CNS depressants (e.g., alcohol, benzodiazepine, antianxiety, or hypnotic agents)-causes additive sedation. MAO inhibitors- can cause fatal reactions. Warfarin: May increase anticoagulant effect. Administration/Interventions/Evaluation of Effectiveness/Laboratory Work  Monitor LFTs, cholesterol and increased triglyceride levels- may increase all three.  Monitor WBCs  Administer orally Patient Education: What will the safe nurse teach the client to DO or expect or report  Advise families and caregivers to closely observe patient for increasing suicidal thinking and behavior. 

Teach patient to recognize and immediately report signs and symptoms of serotonin toxicity.

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Instruct patient to take drug at bedtime. Caution patient to avoid hazardous activities if feeling too sleepy.

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Tell patient to report signs and symptoms of infection, such as fever, chills, sore throat, mucous membrane irritation, or flulike syndrome.

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Instruct patient not to use alcohol or other CNS depressants while taking drug.

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Instruct patient not to take other drugs or stop drug abruptly without prescriber’s approval.

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Tell female patient of childbearing potential to report suspected pregnancy immediately and to notify prescriber if breastfeeding.

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Instruct patient to remove ODTs from blister pack and place immediately on tongue. Tell patient to be sure hands are clean and dry when touching the tablet.

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Advise patient not to break or split tablet.

Cite Reference: Lippincott Advisor for Education; Frandsen & Pennington: Abrams' Clinical Drug Therapy: Rationales for Nursing Practice, Eleventh Edition...