MSDS Orgo Lab 1 - Lab MSDS for organic chemistry labs 1 and 2 PDF

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Lab MSDS for organic chemistry labs 1 and 2...

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Chemical hazards ANTHRACENE Exposure controls/personal protection  should ensure proper ventilation; need goggles and protective gloves; wear respirator if working with concentrations above the exposure limit Toxicology information  delayed and immediate effects as well as chronic effects from short and long term- exposure: irritating to the eyes and skin First aid measures in case of emergency  - If symptoms persist, call a doctor - If in contact with eyes: rinse immediately with lots of water for at least 15 mins and under the eyelids for 15 mins  get medical attn - If in contact with skin: wash immediately with lots of water for at least 15 mins and under the eyelids for 15 mins  get medical attn - Inhalation: Move to fresh air. Get medical attention if symptoms occur. If not breathing, give artificial respiration - Ingestion: Do not induce vomiting. Obtain medical attention BENZOIC ACID Exposure controls/personal protection  wear goggles and protective gloves; use respirators when using in concentrations greater than the exposure limit Toxicology information  Delayed and immediate effects as well as chronic effects from short and long-term exposure: risk of serious damage to eyes, irritating to the skin First aid measures in case of emergency  - Eye Contact: Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Immediate medical attention is required. - Skin Contact: Wash off immediately with plenty of water for at least 15 minutes. Obtain medical attention. - Inhalation: Remove from exposure, lie down. Move to fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration. Obtain medical attention. - Ingestion: Do not induce vomiting. Obtain medical attention - Most important symptoms: causes eye burns PHTHALIC ACID Exposure controls/personal protection  goggles and protective gloves Toxicology information  no acute toxicity; severe eye irritant; irritating to respiratory system and skin First aid measures in case of emergency  - Eye Contact: Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Get medical attention. - Skin Contact: Wash off immediately with plenty of water for at least 15 minutes. Obtain medical attention. - Inhalation: Move to fresh air. Obtain medical attention. If not breathing, give artificial respiration. - Ingestion: Do not induce vomiting. Obtain medical attention.

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Most important symptoms/effects: Causes eye burns. Causes severe eye damage

RESORCINOL Exposure controls/personal protection  wear appropriate protective eyeglasses or chemical safety goggles and appropriate gloves and clothing to prevent skin exposure; use respirators when using concentrations above exposure limits Toxicology information  irritation: Irritating to respiratory system and skin Causes eye burns First aid measures in case of emergency  - Eye Contact: Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Immediate medical attention is required. - Skin Contact: Wash off immediately with plenty of water for at least 15 minutes. Get medical attention immediately if symptoms occur. - Inhalation: Move to fresh air. If breathing is difficult, give oxygen. Get medical attention immediately if symptoms occur. - Ingestion: Do not induce vomiting. Call a physician or Poison Control Center SODIUM NAPHTHIONATE Exposure controls/personal protection  Toxicology information  Repeated or prolonged contact with the product can cause the elimination of oil from the skin, giving rise to non-allergic contact dermatitis and absorption of the product through the skin. Splatters in the eyes can cause irritation and reversible damage. First aid measures in case of emergency  - Eye contact. If wearing contact lenses, remove them. Wash eyes with plenty of clean and cool water for at least 10 minutes while pulling eyelids up, and seek medical assistance. - Skin contact. Remove contaminated clothing. Wash skin vigorously with water and soap or a suitable skin cleaner. NEVER use solvents or thinners. - Ingestion. If accidentally ingested, seek immediate medical attention. Keep calm. NEVER induce vomiting ETHANOL Exposure controls/personal protection  goggles, appropriate gloves and clothing; respoirators when….; prevent from entering drains Toxicology information  May cause eye, skin, and respiratory tract irritation; Teratogenic effects have occurred in experimental animals; Symptoms of overexposure may be headache, dizziness, tiredness, nausea and vomiting First aid measures in case of emergency  - Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Immediate medical attention is required - Skin Contact: Wash off immediately with plenty of water for at least 15 minutes. Get medical attention immediately if symptoms occur. - Inhalation: Remove from exposure, lie down. Move to fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration. Obtain medical attention.

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Ingestion: Do not induce vomiting. Call a physician or Poison Control Center immediately. Most important symptoms/effects Breathing difficulties. Symptoms of overexposure may be headache, dizziness, tiredness, nausea and vomiting

HEXANE Exposure controls/personal protection  use only under a chemical fume hood; wear appropriate protective eyeglasses/chemical safety goggles and protective gloves; use respirators when working with concentrations above the exposure limit; prevent from entering drains Toxicology information  irritating to eyes and skin; Inhalation of high vapor concentrations may cause symptoms like headache, dizziness, tiredness, nausea and vomiting (acute and delayed effects) First aid measures in case of emergency  - Eye Contact: Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Get medical attention. - Skin Contact: Wash off immediately with plenty of water for at least 15 minutes. If skin irritation persists, call a physician. - Inhalation: Move to fresh air. If not breathing, give artificial respiration. Get medical attention if symptoms occur. Risk of serious damage to the lungs. - Ingestion: Clean mouth with water and drink afterwards plenty of water. Do not induce vomiting. Call a physician or Poison Control Center immediately. If vomiting occurs naturally, have victim lean forward. - Most important symptoms/effects: Breathing difficulties. Inhalation of high vapor concentrations may cause symptoms like headache, dizziness, tiredness, nausea and vomiting TOLUENE Exposure controls/personal protection  wear appropriate protective eyeglasses/chemical safety goggles and protective gloves; use respirators when working with concentrations above the exposure limit; prevent from entering drains Toxicology information  irritating to eyes, skin, and respiratory system; Experiments have shown reproductive toxicity effects on laboratory animals; Causes central nervous system depression: Inhalation of high vapor concentrations may cause symptoms like headache, dizziness, tiredness, nausea and vomiting (effects of both acute and delayed) First aid measures in case of emergency  - Eye Contact: Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Get medical attention. - Skin Contact: Wash off immediately with plenty of water for at least 15 minutes. If skin irritation persists, call a physician. - Inhalation: Move to fresh air. If not breathing, give artificial respiration. Get medical attention if symptoms occur. Risk of serious damage to the lungs.

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Ingestion: Clean mouth with water and drink afterwards plenty of water. Do not induce vomiting. Call a physician or Poison Control Center immediately. If vomiting occurs naturally, have victim lean forward. Most important symptoms/effects: Breathing difficulties. Causes central nervous system depression: Inhalation of high vapor concentrations may cause symptoms like headache, dizziness, tiredness, nausea and vomiting

SALICYLIC ACID Exposure controls/personal protection  goggles, protective gloves and clothing to prevent skin exposure; respirators when working with concentrations above exposure limit Toxicology information  Severe eye irritant First aid measures in case of emergency  - Eye Contact: Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Get medical attention. - Skin Contact: Wash off immediately with plenty of water for at least 15 minutes. If skin irritation persists, call a physician. - Inhalation: Move to fresh air. If not breathing, give artificial respiration. Get medical attention if symptoms occur. - Ingestion: Clean mouth with water and drink afterwards plenty of water. Get medical attention if symptoms occur. - Most important symptoms/effects: Causes severe eye damage CHARCOAL Exposure controls/personal protection  appropriate eyeglasses/goggles, protective gloves and clothing Toxicology information  May cause skin and eye irritation First aid measures in case of emergency  - Eye Contact: Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Get medical attention. - Skin Contact: Wash off immediately with plenty of water for at least 15 minutes. Get medical attention immediately if symptoms occur. - Inhalation: Move to fresh air. If not breathing, give artificial respiration. If symptoms persist, call a physician. - Ingestion: Drink plenty of water. Do not induce vomiting. Get medical attention if symptoms occur.

Procedure Part 1: solubility tests The following steps will be conducted for all 5 compounds (anthracene, benzoic acid, phthalic acid, resorcinol, and sodium salt of 1-naphthylamine-4-sulfonic acid and 4 solvents (ligroin, toluene, ethanol, and water) - Add a spatula tip (approx. 100 mg) of each compound into separate test tubes

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Using a Pasteur pipette, add 3 mL of solvent to the test tubes If soluble, the solute should dissolve in the solvent If the solute does not dissolve, use the steam bath to heat the test tube o If it dissolves completely = solute is soluble in hot solvent o If it partially dissolves = solute is moderately soluble  Add small amounts of solvents while heating until the solution is complete Run cold water over the test tubes to cool the solutions If needed, evaporate some of the solvent using the steam bath to allow for crystallizations Record observations and make suggestions as to which solvents should be paired for the recrystallization of each compound

Part 2: purification and crystallization of salicylic acid - End goal: to purify 1 g of salicylic acid containing 0.2% Alizarin Yellow R using recrystallization - Add 1 g of the salicylic acid and 25 mL of distilled water in a 150 mL beaker - Swirl the beaker on a hot plate until boiling point is reached - Add water to the beaker, 2 mL at a time until the sample is fully dissolved o Record the amount of water needed for this to occur - As the beaker is still on the hot plate, add an excess of 50-100% of distilled water needed to dissolve the solution into the beaker to avoid difficulties in filtration later - Remove the beaker form the hot plate and swirl it - Add double the amount of decolorizing charcoal calculated to beaker - Place the beaker on the hot plate and reheat it while filtering the solution by gravity using fluted filter paper o Add a few drops of water to the paper to prevent the solution from crystallizing in the cold filter paper - Rinse the beaker with water and cool - Once the filtered flask has reached room temperature, place it in an ice bath to promote more crystallization - Filter the product using suction o Ensure that the rubber fitting is placed tightly and the vacuum is turned on gently o Ensure that the filter paper is wet to form a tight seal - Use water to wash out the flask in case the product was not properly rinsed out and swirl o Filter by suction again - Air-dry the crystals in a labeled beaker overnight and weigh sample for IR spectrum - Calculate % recovery

MSDS LAB 2 CHLOROFORM Exposure controls/personal protection  should ensure proper ventilation; need goggles and protective gloves; wear respirator if working with concentrations above the exposure limit Toxicology information  Irritating to eyes and skin - STOT - single exposure Central nervous system (CNS) Respiratory system - STOT - repeated exposure Heart Liver Kidney - Symptoms of overexposure are dizziness, headache, tiredness, nausea, unconsciousness, cessation of breathing: Causes central nervous system depression - Tumorigenic effects have been reported in First aid measures in case of emergency  - Eye contact: Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. In the case of contact with eyes, rinse immediately with plenty of water and seek medical advice. - Skin Contact Wash off immediately with plenty of water for at least 15 minutes. Immediate medical attention is required. - Inhalation Move to fresh air. If not breathing, give artificial respiration. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Immediate medical attention is required. - Ingestion Do not induce vomiting. Call a physician or Poison Control Center immediately. - Most important symptoms/effects . Symptoms of overexposure are dizziness, headache, tiredness, nausea, unconsciousness, cessation of breathing: May cause decreases in blood pressure and other cardiac effects: Symptoms may be delayed POTASSIUM BROMIDE Exposure controls/personal protection  need goggles and protective gloves; wear respirator if working with concentrations above the exposure limit Toxicology information  Irritating to eyes May cause irritation of respiratory tract First aid measures in case of emergency  - Eye Contact: Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Get medical attention. - Skin Contact Wash off immediately with plenty of water for at least 15 minutes. Obtain medical attention. - Inhalation Move to fresh air. If breathing is difficult, give oxygen. Obtain medical attention. - Ingestion Clean mouth with water and drink afterwards plenty of water. Get medical attention if symptoms occur

Purpose: to gain familiarity with infrared spectroscopy Procedure – Preparation of KBr pellet - Take the pellet press and wash the screws with water - Place the press and screws in the heat guns; ensure that hot air is coming out - Once the time is complete, remove the metal parts from the heat guns and cool it down - Weigh 1.5-2.0 mg of sample but do not weight by difference - Place it in a mortar that is cleaned with chloroform - Add one scoop of KBr from the oven - Grind the weighed sample and the KBr together and put it on a piece of weighing paper - Place one screw in half way and set it in the holder - Place the sample and the KBr into the press and insert the other screw - Tighten the screw using a torque wrench until the pressure researches 30 ft lbs o Let it sit for a moment o Repeat this process - Remove the 2 screws and take the press that contains the KBr pellet and scan it in a FTIR Spectrometer for analysis - Compare results to the literature

During the lab 1. interpretation of the IR of salicylic acid - List the wave number positions of all the significant peaks - Indicate which peaks are associated with a particular structural feature in salicylic acid - Compare to the spectrum found online

2. interpretation of the IR of unknown compounds These steps should be done for all 4 unknown compounds - Examine the diagnostic region of the spectrum (4000 – 6000) and determine which functional groups are present - Compare the fingerprint region (1600-600) to the authentic spectra of the different compounds - Return to the diagnostic region and label the peaks in each region with the corresponding functional group

LAB 3 2- NAPHTHOL Exposure controls/personal protection  appropriate eyeglasses/goggles, protective gloves and clothing Toxicology information  no information available First aid measures in case of emergency  - Eye contact: Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Get medical attention. - Skin contact: Wash off immediately with plenty of water for at least 15 minutes. Get medical attention immediately if symptoms occur. - Inhalation: Move to fresh air. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Immediate medical attention is required. If not breathing, give artificial respiration. - Ingestion: Do not induce vomiting. Call a physician or Poison Control Center immediately. - Most important symptoms/effects: No information available. - Notes to Physician: Treat symptomatically HYDROQUINONE DIMETHYL ETHER Exposure controls/personal protection  appropriate eyeglasses/goggles, protective gloves and clothing Toxicology information  no information available First aid measures in case of emergency  - Eye contact: Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. - Skin contact: Wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes. - Inhalation: Remove from exposure, lie down. Move to fresh air. - Ingestion: Do not induce vomiting. Never give anything by mouth to an unconscious person. Drink plenty of water. If possible drink milk afterwards. - Most important symptoms/effects: No information available. - Notes to Physician: Treat symptomatically

DIETHYL ETHER Exposure controls/personal protection  appropriate eyeglasses/goggles, protective gloves and clothing

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Eye Protection: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Hand Protection: Wear appropriate protective gloves and clothing to prevent skin exposure.

Toxicology information  - Irritation: irritating to eyes and skin - Carcinogicity: table? - Mutagenic effects: mutagenic effects have occurred in experimental animals -

Symptoms / effects,both acute and delayed: Inhalation of high vapor concentrations may cause symptoms like headache, dizziness, tiredness, nausea and vomiting

First aid measures in case of emergency  - Eye contact: If symptoms persist, call a physician. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Get medical attention. - Skin contact: Wash off immediately with plenty of water for at least 15 minutes. If skin irritation persists, call a physician. - Inhalation: Move to fresh air. If not breathing, give artificial respiration. Get medical attention if symptoms occur. - Ingestion: Clean mouth with water and drink afterwards plenty of water. - Most important symptoms/effects: Breathing difficulties. Inhalation of high vapor concentrations may cause symptoms like headache, dizziness, tiredness, nausea and vomiting - Notes to Physician: Treat symptomatically

HYDROCHLORIC ACID Exposure controls/personal protection  appropriate eyeglasses/goggles, protective gloves and clothing Toxicology information  Causes burns by all exposure routes. The table below indicates whether each agency has listed any ingredient as a carcinogen. Product is a corrosive material. Use of gastric lavage or emesis is contraindicated. Possible perforation of stomach or esophagus should be investigated: Ingestion causes severe swelling, severe damage to the delicate tissue and danger of perforation First aid measures in case of emergency  - Eye contact: Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Immediate medical attention is required.

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