Quiz 1 Answer Key PDF

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First quiz in 3310, questions and answers. ...

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NETI D KEYA

BI OMG 3310

QUI Z1a

9/ 11/ 13

1.( 11pt s )Dr aw t hest r uct ur eoft hedi pept i deSer Cy satpH10.Show al lat omsexpl i ci t l y.Labelbot h andbot h car bons .Show t hecor r ect f or m ofeachi oni z abl egr oup.

2.( 5pt s)Answert hes ePy MOLques t i onsaboutt heEbol avi r uspr ot ei n s hownont her i ght ,whi chhasal l pr ol i ner es i duessel ect edand hi ghl i ght edi nr ed: LOOKUPATTHESCREENTOSEETHECOLORI MAGE a.Ci r cl et hecommandusedt osel ectt hepr ol i ner es i dues . i . Sel ectr esnpr o i i .Chooseal l pr ol i ne i i i .&sr es i dueP i v .Bui l dsel ect i on( pr o)

Us et hesepKav al ues: t er mi nal COOH 4 + t er mi nal NH3 9 RGROUPS: As p4 Gl u4 Cys8 Ty r 10 Hi s7 L ys 10 Ar g12

b.Whati st hi sr epr esent at i onoft hepr ol i ner es i duescal l ed? i . SpaceFi l l i ng i i .Bl oc k i i i .CPKmodel i v .Spher es c.Di r ect l yont hefigur et ot her i ght ,CI RCLEt hebut t onyou woul dus et ocol ort hepr ol i nesr edasshown.

3.( 9pt s)Hemogl obi nhasaL y sandat er mi nalcar boxy l t hatar ecl oset oeac hot her .Es t i mat et hef r act i onofal l t hes eLy s c ar boxy l nei ghbor st hat woul dbei nani onpai rbondatt hef ol l owi ngpHval ues .Ci r cl et heonebestanswerf r om t hechoi cest hatf ol l ow t hepH. atpH3 { 1. 0} { 0} { 0. 1} { 0. 01} { 0. 9} { 0. 5} { 0. 83} atpH4 { 1. 0} { 0} { 0. 1} { 0. 01} { 0. 9} { 0. 5} { 0. 83} atpH10 { 1. 0} { 0} { 0. 1} { 0. 01} { 0. 9} { 0. 5} { 0. 83}

4.( 3pt s)Usecompl et enamesor3l et t erabbr ev i at i onst oans wert heseques t i ons: a.Name2ami noaci dr esi duest hatwoul dal mos tal way sbedr i v eni nt ot hepr ot ei ni nt er i orbyt hehy dr ophobi ci nt er act i on. Phe,Met ,I l e,Leu,Val ,Cy s,Tr p,Al a______________ b.Name2ami noaci dr esi duest hatwoul dal mos tneverbedr i v eni nt ot hepr ot ei ni nt er i orbyt hehy dr ophobi ci nt er act i on. __Hi s ,Gl n,As n,Gl u,Ly s ,As p,Ar g___________ c.Nameoneami noaci dt hati ss ubj ectt ot hecommonchemi calmodi fi c at i onofphosphor y l at i on. ___Ser ,Thr ,Tyr _____

5.( 2pt s)Mat cht hel ef tcol umnwi t ht hebestr i ghtcol umndesc r i pt i on.Useeachr i ghtcol umnl et t erONCE. A apr ot ei nwi t houti t spr ost het i cgr oup

A.apopr ot ei n

D mustbec l osel yr el at edt oanot herpr ot ei n

B.enzy me

C pr ot ei npr i mar yst r uct ur e

C.sequenc eofami noac i ds

Bk i nase

D.i sozy me

NETI D KEYB

BI OMG 3310

QUI Z1b

9/ 11/ 13

1.( 11pt s)Dr awt hes t r uct ur eoft hedi pept i deAs nL y satpH8.Dr aw al lat oms.Label bot h andbot h car bons .Show t hecor r ectf or m ofeach i oni zabl egr oup.

2.( 5pt s)Answert hes ePy MOLques t i onsaboutt heEbol avi r uspr ot ei n s hownont her i ght ,whi chhasal l pr ol i ner es i duessel ect edand hi ghl i ght edi nr ed:

Us et hesepKav al ues: t er mi nal COOH 3 + 9 t er mi nal NH3 RGROUPS: As p3 Gl u3 Cys8 Ty r 10 Hi s7 L ys 10 Ar g12

LOOKUPATTHESCREENTOSEETHECOLORI MAGE a.Ci r cl et hecommandusedt osel ectt hepr ol i ner es i dues . i . Choos eal l pr ol i ne i i .Sel ectr esnpr o i i i .Bui l dsel ect i on( pr o) i v .&sr es i dueP b.Whati st hi sr epr esent at i onoft hepr ol i ner es i duescal l ed? i . Bl ock i i .SpaceFi l l i ng i i i .Spher es i v .CPKmodel c.Di r ect l yont hefigur et ot her i ght ,CI RCLEt hebut t onyou woul dus et ocol ort hepr ol i nesr edasshown.

3.( 9pt s)Hemogl obi nhasaL y sandat er mi nalcar boxy l t hatar ecl oset oeac hot her .Es t i mat et hef r act i onofal l t hes eLy s c ar boxy l nei ghbor st hat woul dbei nani onpai rbondatt hef ol l owi ngpHval ues .Ci r cl et heonebestanswerf r om t hechoi cest hatf ol l ow t hepH. atpH3 { 1. 0} { 0} { 0. 1} { 0. 01} { 0. 9} { 0. 5} { 0. 83} atpH4 { 1. 0} { 0} { 0. 1} { 0. 01} { 0. 9} { 0. 5} { 0. 83} atpH9 { 1. 0} { 0} { 0. 1} { 0. 01} { 0. 9} { 0. 5} { 0. 83}

4.( 2pt s)Ref ert ot hegr aphatt her i ght .Wr i t eanswer satt hebot t om oft hegr aph. a.Under l i net he4r es i duest hatar emostst r ongl ydr i v eni nt ot hepr ot ei ni nt er i orby t hehydr ophobi ci nt er act i on. b.Wr i t eSundert hesul f ur c ont ai ni ngr es i dues .

5.( 3pt s)Ci r c l eTi ft r ue,Fi ff al s e: T/F Wat erhasmor eway st oHbondt oi t s el fwhennonpol arr es i duesar edr i v eni nt o t hepr ot ei ni nt er i or . T/F Wheni oni z ed,aGl ur es i duei sl i k el yt obef oundont hepr ot ei next er i or . T/F Nonpol arr es i duesbi ndst r ongl yt oeachot her ,t her ef or ear edr i v eni nt ot he pr ot ei ni nt er i or .

_______ S

S

NETI D KEYC

BI OMG 3310

QUI Z1c

9/ 11/ 13 Us et hesepKaval ues :

1.( 3pt s)Consi dert heami noac i dsgl y ci ne,l y s i ne,andgl ut amat eatpH7. Gl yLy s Gl ui sat r i pept i de.Wr i t ei nt hecor r ectans wer sbel ow: a.Compar edt ot hef r eeAA,howmany+char gesar el os twhent het r i pept i def or ms ?2 b.Compar edt ot hef r eeAA,howmany-char gesar el ostwhent het r i pept i def or ms ?2 c .Compar edt ot hef r eeAA,t het r i pept i dehas( c i r c l et hecor r ectans wer )[ mor e l es s ~same]sol ubi l i t yi nwat er .

2.( 2pt s)Mat cht hel ef tcol umnwi t ht hebestr i ghtcol umndesc r i pt i on.Useeachr i ghtcol umnl et t erONCE. B apr ot ei nt oget herwi t hi t spr ost het i cgr oup

A.wat erent r opyi nc r eases

D mustbecl os el yr el at edt oanot herpr ot ei n

B.hol opr ot ei n

C canber ecogni z edf r om pr i mar yst r uct ur e

C.z i ncfi nger

A hydr ophobi ci nt er act i on

D.i sozy me

t er mi nal COOH t er mi nal NH3+ RGROUPS: As p5 Gl u5 Cys8 Ty r 10 Hi s7 L ys 10 Ar g12

5 9

3.( 5pt s)Answert hes ePy MOLques t i onsaboutt heEbol avi r uspr ot ei n s hownont her i ght ,whi c hhasal l pr ol i ner esi duess el ect edand hi ghl i ght edi nr ed: LOOKUPATTHESCREENTOSEETHECOLORI MAGE a.Ci r cl et hecommandusedt osel ectt hepr ol i ner es i dues . i . Choos eal l pr ol i ne i i .&sr es i dueP i i i .Bui l dsel ect i on( pr o) i v .Sel ectr es npr o b.Whati st hi sr epr esent at i onoft hepr ol i ner es i duescal l ed? i . Spher es i i .SpaceFi l l i ng i i i .Bl oc k i v .CPKmodel c.Di r ect l yont hefigur et ot her i ght ,CI RCLEt hebut t onyou woul dus et ocol ort hepr ol i nesr edasshown.

4.( 9pt s)Hemogl obi nhasaL y sandat er mi nalcar boxy l t hatar ecl oset oeac hot her .Es t i mat et hef r act i onofal l t hes eLy s c ar boxy l nei ghbor st hat woul dbei nani onpai rbondatt hef ol l owi ngpHval ues .Ci r cl et heonebestanswerf r om t hechoi cest hatf ol l ow t hepH. atpH3 { 1. 0} { 0} { 0. 1} { 0. 01} { 0. 9} { 0. 5} { 0. 83} atpH4 { 1. 0} { 0} { 0. 1} { 0. 01} { 0. 9} { 0. 5} { 0. 83} atpH9 { 1. 0} { 0} { 0. 1} { 0. 01} { 0. 9} { 0. 5} { 0. 83}

5.( 11pt s)Dr awt hes t r uct ur eoft hedi pept i deMet As natpH6.Dr aw al lat oms.Label bot h andbot h car bons . Show t hecor r ectf or m ofeachi oni z abl egr oup....