Syllabus Chem51 2020 PDF

Preview

Summary

Download Syllabus Chem51 2020 PDF

Description

Chem 51 Fall 2020 Date of revision: 9/9/20

Organic Chemistry I Course Information Instructor

Prof. Krishna Kumar (Pearson P309) ; +1 617 627 5651 Office hours: Tue / Fri, 1:30–3:00 PM or by appointment

Co-instructor

Dr. Sergey Savinov

Office hours: Mon, 3:00-4:30 PM and Thu, 8:00–09:30 AM

Teaching Assistants

Vanessa Jones Office hours: Tue, 7:00–8:00 PM Jamie Liu Office hours: Thu, 5:00–6:00 PM Joseph Romeo Office hours: Fri, 10:30–11:30 AM Özge Ünsal Office hours: Wed, 5:30–6:30 PM

Meeting Times

Tuesdays and Fridays 12:00–01:15 PM (Zoom)

Prerequisites

Introductory General Chemistry: Chem 1/2 or 11/12 sequences or equivalent

Textbook Organic Chemistry by David R Klein 3rd Edition © 2017 John Wiley & Sons, Inc. ISBN: 978-1-119-35160-3 Note: The first and second editions of Klein are not appropriate for this course. The third edition has major (good) revisions of many sections that will be relevant to the topics we will cover. If you need assistance with materials, please contact Prof. Kumar.

Study Aids (1) REQUIRED! MOLECULAR VISIONS Molecular Model Kit #1! by Stephen H. Darling! © 2010 Darling Models, Inc.! ISBN: 978-09648837-3-4 URL: https://www.darlingmodels.com/Individual-Orders-Molecular-Model-Kits/KIT-1B-ISBN-97809648837-3-4-In-a-Plastic-Bag-Organic-I/prod_4.html! (2) RECOMMENDED This resource can be shared among groups (2-3) of students

Student Study Guide and Solutions Manual to accompany Organic Chemistry

!by David R Klein! 3rd Edition! © 2017 John Wiley & Sons, Inc.! ISBN: 978-1-119-42253-2 Recommended for extra help with concepts!

Organic Chemistry As a Second Language, 3e: First Semester Topics by David R Klein! © 2011 John Wiley & Sons, Inc.! ISBN: 978-1118010402 Note: Later editions are acceptable.

Grading Policy General The total number of points in the course equals 1000. These will be split up between quizzes (260 points), 2 mid term exams (190*2 = 380 points) and one final exam (360 points). Note: The bottom three quizzes will be automatically dropped from your score and your top ten scores will be used to make up the 260 points.

Relative Weights Event % of Grade Exam 1 19 Exam 2 19 Final 36 Quizzes 26 Every exam will have two types of scores (RAW and SCALED). The RAW score is simply the number of points that you score on a particular exam, while the scaled score is your performance relative to that of your classmates. In the usual circumstance, the average score will be scaled to the mid "B–" limit. If the average is higher than the "B–" limit, there will be no scaling. The RAW score of any quiz will be counted without conversion (total of 13). The bottom three scores in the quizzes will be dropped and the rest averaged. If you miss a quiz, a 0 will be recorded and considered your score for that quiz. There will be no make up quizzes. The exact conversion scheme (for the scaled score) will be announced after each exam, so that you are aware of how you are doing at any time during the course. The final score is the sum of all points/scores. The final grade will be assigned according to the table given below.

Final score 967-1000 933-966 900-932 867-899 833-866 800-832 767-799 733-766 700-732 667-699 633-666 600-632 < 600

% of max score 97-100 93-97 90-93 87-90 83-87 80-83 77-80 73-77 70-73 67-70 63-67 60-63 < 60

Final course grade A+ A A– B+ B B– C+ C C– D+ D D– F

************** Here is an example of how you can calculate your "current grade" after two exams and six of 13 quizzes:

6 quizzes (out of 13): Exam I: Exam II:

95 points (out of a total 120) 140 points (scaled to 156) 150 points (scaled to 170)

Maximum number of points possible at this time: TOTAL = 500 120 (Quizzes) + 190 (Exam I) + 190 (Exam II) Earned by you : YOUR TOTAL SCORE = 421 95 (Quizzes) + 156 (Exam 1) + 170 (Exam II) GRADE = (421/500)*100 = 84.2% of the Maximum Score "B" is your current grade. ************** CAUTIONARY NOTE: All students are expected to live up to high standards of academic honesty and integrity set for in the code at Tufts. Violation of this code by use of materials and interactions not directly authorized by the instructor during exams and quizzes will have serious implications. Please consult https://students.tufts.edu/studentaffairs/student-code-conduct/academic-integrity-resources for further information. Instructors of classes are *required* to report any suspected cases of violation of academic integrity to the Dean of Student Affairs office. This is not optional – we expect to keep the class fair for every student and you should be aware of the consequences if you violate the code. Note about exams/quizzes taken in a virtual environment: Any suspected activity including such things as hiring outside help or posting exam/quiz questions on platforms that provide “solving” services are closely monitored. If you engage in such activity or collaborate (with other students in the class or outside of it) when not explicity allowed during exams/quizzes, your case will automatically be reported to the Dean of Student Affairs office. In summary, do *not* cheat. We are committed to keeping the course fair for every student in the class.

Regrades Only written regrade requests will be accepted. Regrade requests will be only entertained if submitted within 36 hours after the exams have been returned. Briefly state your reason(s) for requesting the regrade. The regrade request will be considered carefully but the entire exam will be regraded regardless of whether additional points are awarded on the request. Only examinations that were written in ink will be accepted for regrades. Be aware that I reserve the right to refuse writing letters of recommendation for students who submit frivolous regrade requests. Please also note that quizzes will not be regraded unless there is a clear and direct error on part of the graders. Missed Exams If an exam is missed, the default mechanism is a score of 0 for that exam. The only acceptable excuse note will be one from the Office of the Dean of Students. The note must stipulate the days for which the excuse is valid and must state explicitly that, in the opinion of the Dean, the reason for missing the exam warrants a make-up exam without penalty. The note must be received within one school day from the last day for which the excuse is valid. Upon receipt of such a note, an oral or written (as the circumstance may warrant, and at my discretion) make-up exam will be administered.

Accessibility / Accommodations for Students with Disabilities Tufts University values the diversity of our students, staff, and faculty; recognizing the important contribution each student makes to our unique community. Tufts is committed to providing equal access and support to all qualified students through the provision of reasonable accommodations so that each student may fully participate in the Tufts experience. If you have a disability that requires reasonable accommodations, please contact the StAAR Center (formerly Student Accessibility Services) at [email protected] or +1 617 627 4539 to make an appointment with an accessibility representative to determine appropriate accommodations. Please be aware that accommodations cannot be enacted retroactively, making timeliness a critical aspect for their provision.

Recitation Sections Recitation sections are MANDATORY. They will be problem-solving sessions involving you, your TA, and everyone else who attends your section. These are meant to be “safe areas” that allow you to work

through problems alone or together, at your own pace, without judgment. In these sessions, do not race to an answer! Instead, work out the problems by discussing them with your peers and TA. The point is not just to test your knowledge, but to explicitly discuss and practice specific problem-solving approaches.

Tufts University Policy on Sharing (F2020) Language from the Deans of Academic Advising and Undergraduate Studies

This course is designed for everyone to feel comfortable participating in discussion, asking questions, learning, and facilitating the learning of others. In order for that atmosphere to be maintained, the recordings of our conversations will only be shared with the enrolled students in the class (not posted publicly), and it is prohibited for any of us who have access to the video to share it outside the course. Similarly, we have specifically designed the syllabus, exams, handouts, and lectures for the people who are enrolled in the course this term and those may not be shared outside this course. It is against Tufts policy for anyone to share any content made available in this course including course syllabi, reading materials, problems sets, videos, handouts, and exams with anyone outside of the course without the express permission of the instructor. This especially includes any posting or sharing of videos or other recordings on publicly accessible websites or forums. Any such sharing or posting could violate copyright law or law that protects the privacy of student educational records. If you have any questions or if you are looking for additional teaching resources, please visit our AS&E Teaching Resource page or coronavirus.tufts.edu/community-messages.

Calendar Date Sep 08 (Tue) Sep 11 (Fri) Sep 15 (Tue) Sep 18 (Fri) Sep 22 (Tue) Sep 25 (Fri) Sep 29 (Tue) Oct 02 (Fri) Oct 06 (Tue) Oct 09 (Fri) Oct 13 (Tue) Oct 16 (Fri) Oct 20 (Tue) Oct 23 (Fri) Oct 27 (Tue) Oct 30 (Fri)

Nov 03 (Tue) Nov 06 (Fri) Nov 10 (Tue) Nov 13 (Fri) Nov 17 (Tue) Nov 20 (Fri) Nov 24 (Tue) Nov 27 (Fri) Dec 01 (Tue) Dec 04 (Fri) Dec 08 (Tue) Dec 11 (Fri) Dec 12-14 Dec 15

Lecture Introduction, review, drawing molecules Klein 1 and 2, notes Resonance, introduction to acidity Klein 2.7–2.11, Klein 3.1–3.4 Acidity and reactivity Klein 3.5–3.9 Conformational analysis Klein 4.1–4.14 Stereoisomerism Klein 5 Chemical reactivity/mechanism Klein 6.1-6.7; Klein 6.8-6.12 Cont’d Substitution reactions (SN2) Klein 7.1–7.5 Exam 1 Alkenes and E2 reactions Klein 7.6–7.8 SN1 / E1 reactions, product landscape Klein 7.9, 7.11 Substitutions/eliminations at alcohols Klein 7.12, 7.13 Addition reactions Klein 8.1–8.8, 8.13 Synthesis: subs, elims and addns Klein 8.14, 11.2 Oxidation / reduction Klein 12.1–12.4, 12.9–12.11 Synthesis: C–C bond formation, “protecting groups” Klein 12.6–12.7, 12.13, 19.10 Exam 2 Aldehydes and ketones Klein 19.1–19.7 No Class Cont’d Klein 19.11, 19.12 Carboxylic acid derivatives Klein 20.1–20.9 Cont’d Klein 20.10–20.14 Enols and enolates Klein 21.1–21.2, 21.5 No Class Enols and enolates Enols and enolates Klein 21.3–21.4, 21.7 Michael/conjugate additions, amines Klein 21.6–21.7, 22.1, 22.3, 22.6–22.7 Review and conclusion Reading Period Final Exam

Notes Classes begin

Last day to ADD classes

Last day to DROP classes

Substitute Wed schedule on Tue

Withdraw deadline P/F option

Day after Thanksgiving Day

Classes end 12-2:30 PM

Department of Chemistry Undergraduate Majors

Educational Goals and Required Knowledge and Skills

General education goals in chemistry: Communication. The ability to write, display information, and orally communicate in a scientific format. Primary literature. The ability to search for, read and understand primary sources of scientific literature. Understanding data. The ability to understand chemistry data, how it is produced, and how it is applied. Quantitative analysis. The ability to apply quantitative measurement and analytical laboratory techniques to scientific problems. 5. Mathematical tools. The ability to apply mathematical tools to chemistry problems that often involve multiple variables, statistics, and symmetry. 6. Scientific method. The ability to develop a hypothesis, design experiments to test that hypothesis, execute experiments, interpret data, and refine a hypothesis in light of new data. 7. Chemistry as the central and molecular science. Understanding how chemists solve problems across disciplines by designing, synthesizing, and analyzing molecules with defined structure and function. 8. Critical evaluation. The ability to critique scientific claims in the technical and popular press with respect to accuracy, interpretation, and application. 9. Integrity. The development of honesty, responsibility, and integrity with respect to the generation and interpretation of data as a scientist and as a citizen. 10. Science and society. The development of a sense of responsibility for promoting education, diversity and functional literacy in science within the larger community. 1. 2. 3. 4.

Knowledge and skills requirements: Problem-solving skills, including logical reasoning, diligence, and attention to quality, consistency, and thoughtfulness in one’s work 2. Structure. Three-dimensional molecular structure and chemical bonding and their origins in the electronic structure of matter 3. Properties and reactivities of important chemical classes, and their uses and preparation 4. Energy and thermodynamics 5. Chemical equilibria including acids, bases and solubility 6. Chemical reactions, stoichiometry and mechanisms 7. Reaction kinetics 8. Oxidation, reduction, and electron transport 9. Chemical basis of biological function 10. Experimental techniques. Knowledge of, and safe practices in, analytical and preparatory laboratory techniques, including synthesis of molecules and/or materials 11. Hands-on laboratory experience 1.

Department of Chemistry Undergraduate Majors

Learning Goals and Skills and Competencies

The Chemistry Department has identified a set of learning goals and a list of skills and competencies we expect of our graduating majors. The list appears in full on our department’s website, http://chem.tufts.edu While each individual course in our curriculum may not address all items on the lists, completion of all required courses leading to the major will. The grid below indicates which of the goals, skills, and competencies will be addressed in this course. Entries of 1, 2, or 3 indicate that the topic will be a primary, secondary, or tertiary focus of the course. Course: Chem51 Semester: Fall 2020

3

1

2

1

1

1

SCIENCE & SOCIETY

INTEGRITY

CRITICAL EVALUATION

CHEMISTRY AS CENTRAL & MOLECULAR SCIENCE

SCIENTIFIC METHOD

MATHEMATICAL TOOLS

UNDERSTANDING DATA

PRIMARY LITERATURE

COMMUNICATION 2

QUANTITATIVE ANALYSIS

Learning Goals

2

2

2

2

1

2

2

2

HANDS-ON LABORATORY EXPERIENCE

1

EXPERIMENTAL TECHNIQUES

REACTION KINETICS

CHEMICAL REACTIONS

CHEMICAL EQUILIBRIA

ENERGY AND THERMODYNAMICS

PROPERTIES & REACTIVITIES 1

CHEMICAL BASIS OF BIOLOGICAL FUNCTION

1

OXIDATION, REDUCTION, AND e - TRANSPORT

1

STRUCTURE

PROBLEM-SOLVING SKILLS

Skills and Competencies...