5. Tumor Markers (Table) PDF

Title	5. Tumor Markers (Table)
Author	Joyce Ann Magsakay
Course	Clinical Chemistry 2
Institution	Our Lady of Fatima University
Pages	1
File Size	159.3 KB
File Type	PDF
Total Downloads	103
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Summary

Description

ENZYME TUMOR MARKERS TUMOR MARKER

TUMOR TYPE

PROSTATE-SPECIFIC ANTIGEN

Prostate CA

NEURON-SPECIFIC ENOLASE

Neuroendocrine Tumors

LACTATE DEHYDROGENASE (LDH)

Hematologic Malignancies Hepatocellular CA, Metastatic CA of Bone, Osteosarcoma, Lymphoma, Leukemia

ALKALINE PHOSPHATASE (ALP)

METHOD Immunoassay Radioimmunoassay, Immunohistochemistry Enzyme Assay Enzyme Assay

SERUM PROTEIN TUMOR MARKERS TUMOR MARKER SERUM M-PROTEIN

TUMOR TYPE Plasma cell Dyscrasias

METHOD Serum Protein Electrophoresis

SERUM FREE LIGHT CHAINS

Plasma cell Dyscrasias

Immunoassay

B2-MICROGLOBULIN

Hematologic Malignancies

Immunoassay

RECEPTOR TUMOR MARKERS TUMOR MARKER

TUMOR TYPE

METHOD

ESTROGEN RECEPTOR

Breast CA

Immunohistochemistry

PROGESTERONE RECEPTOR

Breast CA

HER-2/NEU

Breast, Ovary, GI Tumors

EPIDERMAL GROWTH FACTOR RECEPTOR

Head, Neck, Ovary, Cervical CA

Immunohistochemistry Immunohistochemistry, Fluorescence-in-situ, Hybridization Immunohistochemistry

CARBOHYDRATE & CANCER ANTIGEN TUMOR MARKERS TUMOR MARKER

TUMOR TYPE

METHOD

CA 19-9

Adenocarcinoma, GI CA

Immunoassay

CA 15-3

Metastatic Breast CA

Immunoassay

CA 27-29

Metastatic Breast CA

Immunoassay

CA-125

Ovarian CA

Immunoassay

ENDOCRINE TUMOR MARKERS TUMOR MARKER

TUMOR TYPE

METHOD

ADRENOCORTICOTROPIC HORMONE (ACTH)

Pituitary Edema

Immunoassay

ANTI-DIURETIC HORMONE (ADH)

Posterior Pituitary Tumors

Immunoassay

C-PEPTIDE

Insulin-secreting Tumors Medullary Thyroid CA (MTC) & Neuroendocrine Tumors Pheochromocytoma (Neuroendocrine Tumors of the Adrenals) Adrenal Tumors

Immunoassay, ELISA

CALCITONIN CHROMOGRANIN A CORTISOL

Immunoassay ELISA, RIA Immunoassay

GASTRIN

Neuroendocrine Tumors

Immunoassay

GROWTH HORMONE

Pituitary Adenoma, ectopic GH-secreting Tumors

Immunoassay

HOMOVANILLIC ACID (HVA)

Neuroblastoma, Pheochromocytoma, Paraganglioma

HPLC

HYDROXYINDOLEACETIC ACID (5-HIAA)

Carcinoid Tumors

HPLC

METANEPHRINES

Neuroblastoma, Pheochromocytoma, Paraganglioma

HPLC

PARA-THYROID HORMONE (PTH)

Parathyroid Adenoma

Immunoassay

PROLACTIN (PRL)

Pituitary Adenoma

Immunoassay

VANILLYLMANDELIC ACID (VMA)

Neuroblastoma, Pheochromocytoma, Paraganglioma

HPLC...