Azithromycin ATI - ATI PDF

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Medication

Apo-Azithromycin AzaSite Novo-Azithromycin Zithromax STUDENT NAME: _______________________________________________ Zithromax TRI-PAK azithromycin Zithromax Z-PAK MEDICATION GENERIC:___________________________________TRADE:______________________________________ Macrolide. PHARMACOLOGIC CLASS: _________________________________________________________

PURPOSE OF MEDICATION MECHANISM OF ACTION: Binds to ribosomal receptor sites of susceptible organisms, inhibiting RNAdependent protein synthesis. Therapeutic Effect: Bacteriostatic or bactericidal, depending on drug dosage

THERAPEUTIC CLASS & USE: IV/PO: Treatment of susceptible infections due to Chlamydia pneumoniae, C. trachomatis, H. influenzae, Legionella, M. catarrhalis, Mycoplasma pneumoniae, N. gonorrhoeae, S. aureus., S. pneumoniae, S. pyogenes, including mild to moderate infections of upper respiratory tract (pharyngitis, tonsillitis), lower respiratory tract (acute bacterial exacerbations, COPD, pneumonia), uncomplicated skin and skin-structure infections, sexually transmitted diseases (nongonococcal urethritis, cervicitis due to C. trachomatis), chancroid. Prevents disseminated Mycobacterium avium complex (MAC). Treatment of mycoplasma pneumonia, community-acquired pneumonia, pelvic inflammatory disease (PID). Prevention/treatment of MAC in pts with advanced HIV infection. OFFLABEL: Prophylaxis of endocarditis. Prevention of pulmonary exacerbations in pts with cystic fibrosis. Ophthalmic: Treatment of bacterial conjunctivitis caused by susceptible infections due to H. influenzae, S. aureus, S. mitis, S. pneumoniae. Prevention of pulmonary exacerbations in pts with cystic fibrosis

CONTRAINDICATIONS & PRECAUTIONS: Contraindicated in: * Hypersensitivity to azithromycin, erythromycin, or other macrolide anti-infectives; * History of cholestatic jaundice or hepatic dysfunction with prior use of azithromycin; * QT interval prolongation, hypokalemia, hypomagnesemia, or bradycardia; * Concurrent use of quinidine, procainamide, dofetilide, amiodarone, or sotalol. Use Cautiously in: * Severe hepatic impairment (dose adjustment may be required); * Severe renal impairment (CCr...