BY2IM1 MCQ Sample/practice exam, questions and answers PDF

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(1) The basic immunoglobulin unit is composed of: A) 2 identical heavy and 2 identical light chains. B) 2 identical heavy and 2 different light chains. C) 2 different heavy and 2 identical light chains. D) 2 different heavy and 2 different light chains. E) Non-covalently bound polypeptide chains. (2) IgE: A) B) C) D) E)

Is abundant in saliva. Binds strongly to mast cells. Cannot bind to macrophages. Activates the complement cascade. Has an insignificant role in worm infestations

(3) The Fab region of an Ig is responsible for: A) C1q fixation. B) Binding to antigen. C) Binding to Fc receptors. D) Binding to macrophages. E) The ability of Ig to cross the human placenta. (4) Peptides produced by processing of cytosolic proteins largely: A) Are generated in late endosomal vacuoles. B) Enter the endoplasmic reticulum by diffusion. C) Are presented at the cell surface with MHC class II to CD4 T-helpers. D) Are presented at the cell surface with MHC class II to CD8 cytotoxic T-cells. E) Are presented at the cell surface with MHC class I to CD8 cytotoxic T-cells (5) Lymphocytes: A) Enter the tissues and remain there for the rest of their life. B) When mature are only found in secondary lymphoid organs. C) Recirculate between blood and lymphoid tissues. D) Are only educated in the thymus. E) When present in the lymph are called veiled cells. (6) C3b: A) Is chemotactic B) Is an anaphylatoxin C) Opsonises bacteria D) Directly damages bacteria E) Is the inactive form of C3 (7) The circulation of a two month old breast-fed baby will contain maternal: A) IgA B) IgD C) IgE D) IgG E) IgM (8) Lysozyme: A) Is a cytoplasmic organelle B) Activates complement C) Is a proteolytic enzyme D) Splits peptidoglycan E) Is released by mast cells (9) Polymorphonuclear neutrophils attack bacteria:

A) B) C) D) E)

Exclusively by oxygen-dependent mechanisms Exclusively by oxygen-independent mechanisms By phagocytosis By secreting complement By secreting interferon

(10) The classical and alternative pathways meet at complement component: A) C4 B) C4b C) Factor D D) C5 E) C3 (11) Plasma cells: A) Have surface immunoglobulins B) Are derived from T-cells C) Develop into B-cells D) Secrete large amounts of gamma interferon E) Have a high RNA content (12) T cell surface receptors for antigen partly recognize: A) Cytokines B) MHC C) ADCC D) Antibody E) IL-2 (13) CD8 is a marker of: A). B cells B). Helper T cells C). Cytotoxic T cells D). Activated macrophages E). Neutrophils (14) The secondary, but not the primary, immune response is based on: A) Memory B) The bonus effect of multivalency C) Complement activation D) Mast cell degranulation E) Clonal selection

The answers are: 1. A 2. B 3. B 4. E 5. C 6. C 7. D 8. D 9. C 10. E 11. E 12. B 13. C 14. A...