Calculation practice Exam 1 PDF

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Calculation Practice Exam 1 1. A patient is prescribed 10 mEq of potassium daily. The source of potassium chloride in the pharmacy is 5 mEq/mL in 1 mL vials. How many vials per day is needed for the patient? a. 0.5 vial b. 1 vial c. 2 vials d. 1.5 vials 2. How much elemental iron is present in every 150 mg of ferrous sulfate (FeSO4 • 7H2O)? (Atomic weights are iron = 55.9; sulfur = 32.1; oxygen = 16.0; and hydrogen = 1.0. Iron has valences of +2 and +3) a. 25 mg b. 30 mg c. 48 mg d. 54 mg e. 60 mg 3. A 130-lb patient has a creatinine clearance rate of 40 mL/min. Assuming Drug X is eliminated exclusively by renal mechanisms, what maintenance dose should be administered if the normal maintenance dose is 3 mg/lb of body weight? a. 50 mg b. 100 mg c. 150 mg d. 200 mg e. 250 mg 4. An IV medication is available as 3.5 g/ 500 mL with a strength calculation of 0.25 mg/kg/min is prescribed to a 130-lb patient. What is the infusion rate in mL/hour? a. 2.1 mL/ hr b. 126.6 mL/ hr c. 278.6 mL/ hr d. 6,203.4 mL/ hr 5. Which of the following is an invalid DEA number? a. BT5555555 b. DB1294658 c. AR7532648 d. MA2643713 e. All of the above are valid 6. How many quarts are in two gallons? a. 2 quarts b. 4 quarts c. 8 quarts d. 16 quarts 7. How many fluid ounces are in a quart?

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a. 4 fluid ounces b. 8 fluid ounces c. 16 fluid ounces d. 32 fluid ounces 8. How many teaspoons are in one pint? a. 31.5 b. 47.3 c. 94.6 d. 104.2 9. A patient is prescribed 20 mEq of potassium chloride daily. The source of potassium chloride in the pharmacy is 2 mEq/ mL in 20 mL vials. How many mL per day are needed for this patient? a. 1 mL b. 2 mL c. 10 mL d. 20 mL 10. A patient is prescribed 10 mEq of potassium chloride daily. The source of potassium chloride in the pharmacy is 2 mEq/ mL in 20 mL vials. How many mL per day are needed for this patient? a. 0.5 mL b. 1 mL c. 5 mL d. 10 mL 11. How much sodium chloride is needed to make an isotonic 100 mL solution? a. 0.45 g b. 0.90 g c. 1.32 g d. 1.53 g 12. What volume of diluent (assume sterile water) is needed to make an isotonic solution from 0.45 g of sodium chloride? a. 25 mL b. 50 mL c. 100 mL d. 125 mL 13. The ratio strength of a solution is 1:900 (w/v). What is the percent weight by volume [(w/v)%] of the solution? a. 0.1% b. 1.1 % c. 0.9% d. 9% 14. The ratio strength of a solution is 1:5000 (w/v). What is the percent weight by volume [(w/v)%] of the solution?

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a. 0.02% b. 2 % c. 0.8% d. 8% 15. A vial of tobramycin sulfate contains 40 mg of drug per mL of injection. A patient was given 0.5 mL. How much tobramycin sulfate was administered? a. 10 mg b. 20 mg c. 30 mg d. 40 mg 16. How many days will the following prescription supply? Rx Penicillin VK suspension 250 mg/5 mL Sig. 1 tsp. qid t.a.t. disp 200 mL a. 7 days b. 10 days c. 14 days d. 21 days 17. A medication is available in a 200 mg/5 mL vial. An Rx calls for 150 mg bid × 10d. How many milliliters are needed for a single day? a. 5 mL b. 7.5 mL c. 10 mL d. 75 mL 18. A medication is available in a 200 mg/5 mL multiple-use vial. An Rx calls for 300 mg bid × 10d. How many vials are needed for the full course? a. 15 vials b. 30 vials c. 60 vials d. 75 vials 19. JK is a 42 year-old woman who has a prescription for 32 mEq of oral potassium chloride. However, your pharmacy only has 600 mg controlled-release potassium chloride tablets in stock. How many tablets are required each day to provide this dose? (MW = 75) a. 8 b. 3 c. 2 d. 4 e. 6 20. If a patient has a temperature of 102.2° F, what is the patient's temperature in degrees Celsius? a. 37.6 °C

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b. 38.4 °C c. 39 °C d. 40.1 °C 21. If 500 mL of a 15% (v/v) solution of methyl salicylate in alcohol is diluted to 1500 mL, what will be the percentage strength (v/v)? a. 225% b. 5% c. 45% d. 0.45% 22. A medication is available in a 150 mg/5 mL vial. An Rx calls for 300 mg bid × 10d. How many mL are needed for a single dose? a. 5 mL b. 10 mL c. 50 mL d. 100 mL 23. What is the day supply for this prescription? Amoxicillin 125 mg/5 ml (100 ml) SIG: ss tsp tid a. 2 days b. 100 days c. 25 days d. 13 days e. 10 days 24. What is the percent weight by volume [%(w/v)] if 250 grams of dextrose is dissolved in 300 mL of water to make a final volume of 500 mL? a. 4.5% b. 5% c. 45.45% d. 50% 25. If a prescription reads “Dispense: XVIII capsules,” how many capsules should be dispensed? a. 12 tablets b. 18 tablets c. 22 tablets d. 30 tablets 26. What total quantity of tablets should be dispensed for the following prescription? Rx: Prednisone 5 mg Sig: 10 mg qid × 2 days 10 mg tid × 2 days 10 mg bid × 2 days 5 mg tid × 2 days 5 mg bid × 2 days Then stop. Qty qs a. 23 tablets b. 25 tablets

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c. 46 tablets d. 50 tablets 27. What quantity should be dispensed for the following prescription? Rx: Prednisone 10 mg Sig: 2 tabs bid × 3 days 1 tab bid × 3 days 1 tab qd × 3 days 1/2 tab qd × 3 days Then stop. Qty qs a. 9 tablets b. 10 tablets c. 22 tablets d. 23 tablets 28. How many grams of NaCl are there in 1000 mL of D5W/0.45% NaCl solution? a. 4.5 g b. 0.6 g c. 0.45 g d. 0.25 g 29. How many grams of dextrose are in 1000 mL of D5W/0.45% NaCl solution? a. 100 g b. 50 g c. 20 g d. 15 g 30. How many grams of dextrose are in 500 mL of a 10% dextrose solution? a. 500 g b. 50 g c. 150 g d. 200 g 31. How many grams of NaCl are in 500 mL of 0.9% sodium chloride (NS) solution? a. 5 g b. 2.5 g c. 4.5 g d. 1.5 g 32. How many milligrams of neomycin are in 25 mL of a 1% neomycin solution? a. 250 mg b. 125 mg c. 400 mg d. 500 mg 33. How many grams of amino acids are in 500 mL of a 5% amino acid solution? a. 2.5 g b. 22.5 g c. 25 g

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d. 50 g e. 10 g 34. A pharmacist has 25 mL of 0.5% gentian violet solution. What will be the final ratio strength if he or she dilutes this solution to 600 mL with purified water? a. 1:8 b. 1:200 c. 1:500 d. 1:1000 e. 1:4800 35. An order is written for 1 g of lidocaine in 250 mL of D5W to infuse at 60 mg/hr. What is the correct infusion in (mL/hr)? a. 15 mL/hr b. 20 mL/hr c. 35 mL/hr d. 45 mL/hr 36. An order is written for 25,000 units of heparin in 250 mL of D5W to infuse at 17 mL/hr. How many units of heparin will the patient receive in 6 hours? a. 10,200 units b. 40,000 units c. 10,800 units d. 20,400 units 37. An order calls for 2.5 million units of aqueous penicillin. How many milliliters are needed if the vial concentration is 500,000 units/mL? a. 6 mL b. 2 mL c. 10 mL d. 5 mL 38. How many milliliters are needed for 5 million units of penicillin if the vial concentration is 1 million units per mL? a. 15 mL b. 5 mL c. 10 mL d. 20 mL 39. Valproic acid syrup comes in a 250 mg/5 mL concentration. How many mg are present in 7.5 mL of solution? a. 1000 mg b. 500 mg c. 375 mg d. 250 mg 40. How many milliliters of 250 mg/5 mL valproic acid syrup are needed for a 0.5-g dose? a. 1 mL

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b. 5 mL c. 10 mL d. 15 mL 41. If a drug comes in a 250 mg/1.5 mL solution, how many milliliters are required for a 2 g dose? a. 1.5 mL b. 2 mL c. 4.5 mL d. 6 mL e. 12 mL 42. How many grams of ampicillin are in 3 mL of a 500 mg/1.5 mL solution? a. 1 gram b. 4 grams c. 3.5 grams d. 2 grams 43. How many milliliters contain 2.5 g of cephalothin if the concentration of the solution is 1 g/4.5 mL? a. 16.5 mL b. 13.5 mL c. 14.25 mL d. 11.25 mL 44. How many grams of iodine are in 4 mL of a 50% iodine solution? a. 1 g b. 2 g c. 3 g d. 4 g 45. How many milliliters of a 50% dextrose solution are needed for a 7.5-g dextrose dose? a. 7.5 mL b. 10 mL c. 15 mL d. 20 mL 46. How many grams of sodium are in 50 mL D5W solution? a. 0 b. 1 c. 2.5 d. 3 47. The unit of weight measurement that is the same in both the apothecaries’ and avoirdupois systems is the? a. Dram b. Grain c. Ounce d. Pound

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e. Scrupple 48. One microgram equals one thousand (1000): a. Centigrams b. Grams c. Kilograms d. Nanograms e. Milligrams 49. Calculate the drip rate for 120 mL of IV fluids to be given over a half hour via an IV set that delivers 15 gtt/mL. a. 13 gtt/min b. 25 gtt/min c. 60 gtt/min d. 33 gtt/min e. 50 gtt/min 50. If a patient is given IV fluids at a rate of 25 gtt/min over 1 hour, how much fluid will be administered? The drop factor is 15 gtt/ml. a. 50 mL b. 100 mL c. 125 mL d. 200 mL e. 225 mL 51. In order to achieve better pain control, codeine phosphate 0.7 mL SC × 1 is ordered for a patient. The injectable form of codeine phosphate is available in a concentration of 50 mg/mL. How much codeine will this patient receive in this dose? a. 20 mg b. 30 mg c. 35 mg d. 60 mg e. 100 mg 52. Morphine is ordered for a patient, and the nurse gives him 1.9 mL from a vial with a concentration of 40 mg/2.5 mL. How much morphine was the patient given? a. 5 mg b. 10 mg c. 20 mg d. 30 mg e. 40 mg 53. The vial of hydromorphone that you have in stock has a concentration of 1.5 mg/0.5 mL. If the patient is given 0.7 mL, how much hydromorphone did she receive? a. 1. 8 mg b. 2.1 mg c. 2.2 mg d. 2.4 mg e. 3 mg

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54. What is the concentration (in percent) of a solution containing 20 mEq of potassium chloride per 15 mL of liquid? (MW = 75) a. 10 b. 15 c. 20 d. 25 e. 2.5 55. Diazepam is to be administered by the IV route to an adult patient. It is given at a rate of 5 mg/min over 90 seconds. How much diazepam is given to this patient? a. 5 mg b. 6 mg c. 7.5 mg d. 8 mg e. 10 mg 56. How many milligrams of morphine were given to a patient who received 6.2 mL of a 5 mg/mL solution? a. 31 mg b. 22 mg c. 25 mg d. 35 mg e. 46 mg 57. A nurse wants to give 300 mcg of levothyroxine IV to a patient, from a vial containing 0.4 mg/mL. How many milliliters should be given to the patient? a. 0.6 mL b. 0.8 mL c. 1.0 mL d. 1.2 mL e. 7.5 mL 58. A patient is to take 2.6 mL of oral furosemide, and each teaspoon contains 40 mg. How much furosemide will the patient be taking in their 2.6 mL dose? a. 20.8 mg b. 40 mg c. 33.1 mg d. 16.5 mg e. 24 mg 59. What is the percent weight=weight (%[w/w]) if 250 grams of dextrose is dissolved in 300 mL of water to make a final volume of 500 mL? a. 4.5% b. 5% c. 45.45% d. 50%

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60. According to USP specifications, how many milligrams is equal to 1/2 grain? a. 64.8 mg b. 32.4 mg c. 32.4 g d. 3.24 mg 61. If the adult dose of a drug is 200 mg, what is the estimated dose for a child with a BSA of 0.8 m2, using the BSA estimation method? a. 92 mg b. 150 mg c. 50 mg d. 75 mg 62. If Lanoxin Pediatric Elixir contains 0.1 mg of digoxin per mL, how many mcg of digoxin are in 6 mL elixir? a. 6 mcg b. 60 mcg c. 600 mcg d. 6000 mcg 63. What is the percentage of alcohol in a mixture of 200 mL of 95% v/v alcohol, 1000 mL of 70% v/v alcohol, and 200 mL of 80% v/v alcohol? a. 75% b. 82% c. 0.75% d. 7.5% 64. A TPN order requires 500 mL of D5W. How many mL of D50W should be used if the D5W is not available? a. 450 mL b. 550 mL c. 50 mL d. 25 mL 65. How much sodium chloride is needed to make the following prescription isotonic given E value for zinc sulfate is 0.15? Zinc sulfate 2% Sodium chloride q.s. Purified water q.s 60 mL a. 540 mg b. 1200 mg c. 180 mg d. 360 mg 66. How much elemental iron is present in 500 mg of ferrous sulfate (FeSO4 • 7H2O) with atomic weights are Fe = 55.9; sulfur = 32.1; oxygen = 16.0; and hydrogen = 1.0. Iron has valences of +2 and +3)?

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a. 100.5 mg b. 167.7 mg c. 111.8 mg d. 120 mg 67. What will be the final ratio strength of a solution if one wishes to dilute 100 mL of 0.5% gentian violet solution to 1250 mL with purified water? a. 1:500 b. 1:1000 c. 1:2500 d. 1:5000 68. How many beclomethasone (Qvar) inhalers should be dispensed to provide a 90-day supply? The recommended dose is 168 mcg BID. The commercial inhaler delivers 42 mcg per metered dose and contains 200 inhalations a. 2 inhalers b. 3 inhalers c. 4 inhalers d. 5 inhalers 69. If 6.25 g of boric acid are dissolved in sufficient alcohol to make a total volume of 100 mL, what is the strength of boric acid in the solution in mg/mL? a. 62.5 mg/mL b. 6.25 mg/mL c. 625 mg/mL d. 62.5 g/mL 70. If 50 mL of 4% (w/v) Xylocaine solution are added to 100 mL bag of D5W injection, what is the percentage strength (w/v) of Xylocaine in the final product? a. 1% b. 2.5% c. 1.3% d. 2% 71. A blood glucose reading shows 200 mg% of glucose. Express this value in mg/mL. a. 0.2 mg/mL b. 20 mg/mL c. 2 mg/mL d. 200 mg/mL 72. How many grams of solute are there in 250 g of a 1:50 w/w solution? a. 50 g b. 5 g c. 0.5 g d. 5 mg 73. How many milligrams of drug are there in 50 mL of a 5% w/v solution? a. 0.25 g b. 5 g

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c. 2500 mg d. 250 mg 74. How many milligrams of drug are there in 100 g of a 1:200 w/w mixture? a. 500 mg b. 5 mg c. 5 g d. 5000 mg 75. How many mg of sodium bicarbonate (NaHCO2) contain 400 mg of sodium? a. 1496 mg b. 1.496 mg c. 0.922 mg d. 922 mg 76. What is the percentage (based on weight) of Na in Na2CO3? a. 21.7% b. 43.4% c. 4.34% d. 0.434% 77. How many milligrams of sodium chloride are there in a 2 mmol solution? (MW of NaCl = 58.5) a. 117 mg b. 11.7 mg c. 1.17 mg d. 1.17 g 78. How many millimoles of calcium fluoride are present in 5 g? (MW of calcium fluoride = 78) a. 0.641 mmol b. 6.41 mmol c. 64.1 mmol d. 64.1 mol 79. How many grams of KCl are needed to prepare 50 mmols solution? (MW of KCl = 74.6) a. 3730 mg b. 37.30 mg c. 3.730 g d. 37.30 g 80. What is the percentage strength of 1:200 solution of oil in alcohol? a. 0.5% v/v b. 0.005% v/v c. 5% v/v d. 0.5 mL

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81. If a vitamin solution contains 0.5 mg of fluoride ion in each milliliter, then how many milligrams of fluoride ion would be provided by a dropper that delivers 0.6 mL? (A) 0.30 mg (B) 0.10 mg (C) 1.00 mg (D) 0.83 mg 82. How many chloramphenicol capsules, each containing 250 mg, are needed to provide 25 mg/kg/d for 7 days for a person weighing 200 lb? (A) 90 capsules (B) 64 capsules (C) 13 capsules (D) 25 capsules 83. If 3.17 kg of a drug is used to make 50000 tablets, how many milligrams will 30 tablets contain? (A) 1.9 mg (B) 1900 mg (C) 0.0019 mg (D) 3.2 mg 84. A capsule contains ⅛ gr of ephedrine sulfate, ¼ gr of theophylline, and ¹⁄16 gr of phenobarbital. What is the total mass of the active ingredients in milligrams? (A) 20 mg (B) 8 mg (C) 28 mg (D) 4 mg 85. If 1 fluid ounce of a cough syrup contains 10 gr of sodium citrate, how many milligrams are contained in 10 mL? (A) 650 mg (B) 65 mg (C) 217 mg (D) 20 mg 86. How many capsules, each containing ¼ gr of phenobarbital, can be manufactured if a bottle containing 2 avoirdupois ounces of phenobarbital is available? (A) 771 capsules (B) 350 capsules (C) 3500 capsules (D) 1250 capsules 87. Using the formula for calamine lotion, determine the amount of calamine (in grams) necessary to prepare 240 mL of lotion. Calamine 80 g Zinc oxide 80 g Glycerin 20 mL bentonite magma 250 mL Calcium hydroxide suffi cient quantity to topical solution make 1000 mL

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(A) 19.2 g (B) 140.0 g (C) 100.0 g (D) 24.0 g 88. From the following formula, calculate the amount of white wax required to make 1 lb of cold cream. Determine the mass in grams. cetyl esters wax 12.5 parts White wax 12.0 parts Mineral oil 56.0 parts Sodium borate 0.5 parts Purified water 19.0 parts (A) 56.75 g (B) 254.24 g (C) 54.48 g (D) 86.26 g 89. How many grams of aspirin should be used to prepare 1.255 kg of the powder? Aspirin 6 parts phenacetin 3 parts Caffeine 1 part (A) 125 g (B) 750 g (C) 175 g (D) 360 g 90. A solution contains 1.25 mg of a drug per milliliter. At what rate should the solution be infused (drops per minute) if the drug is to be administered at a rate of 80 mg/hr? (1 mL “30 drops) (A) 64.00 drops/min (B) 1.06 drops/min (C) 32.00 drops/min (D) 20.00 drops/min 91. The recommended maintenance dose of aminophylline for children is 1.0 mg/kg/hr by injection. If 10 mL of a 25-mg/mL solution of aminophylline is added to a 100-mL bottle of 5% dextrose, what should be the rate of delivery in mL/hr for a 40-lb child? (A) 2.30 mL/hr (B) 8.00 mL/hr (C) 18.90 mL/hr (D) 18.20 mL/hr 92. For children, streptomycin is to be administered at a dose of 30 mg/kg of body weight daily in divided doses every 6 to 12 hrs. Th e dry powder is dissolved by adding water for injection, in an amount to yield the desired concentration as indicated in the following table (for a 1-g vial).

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Reconstituting at the lowest possible concentration, What volume (in mL) would be withdrawn to obtain a day’s dose for a 50-lb child? (A) 3.40 mL (B) 22.73 mL (C) 2.50 mL (D) 2.27 mL 93. The atropine sulfate is available only in the form of 1/150 gr tablets. How many atropine sulfate tablets would you use to compound the following prescription? Atropine sulfate 1/200 gr Codeine phosphate ¼ gr Aspirin 5 gr d.t.d. #24 capsules Sig: 1 capsule p.r.n. (A) 3 tablets (B) 6 tablets (C) 12 tablets (D) 18 tablets 94. In 25.0 mL of a solution for injection, there are 4.00 mg of the drug. If the dose to be administered to a patient is 200 (g, what quantity (in mL) of this solution should be used? (A) 1.25 mL (B) 125.00 mL (C) 12.00 mL (D) None of the above 95. How many milligrams of papaverine will the patient receive each day? Rx papaverine hcl 1.0 g Aqua 30.0 mL Syrup tolu, q.s. a.d. 90.0 mL Sig: 1 teaspoon t.i.d. (A) 56.0 mg (B) 5.6 mg (C) 166.0 mg (D) 2.5 mg 96. Considering the following formula, how many grams of sodium bromide should be used in filling this prescription? Rx sodium bromide 1.2 g syrup tolu 2.0 mL syrup wild cherry, q.s. a.d. 5.0 mL d.t.d. #24 (A) 1.2 g (B) 1200.0 g

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(C) 28.8 g (D) 220.0 g 97. How many milliliters of a 7.5% stock solution of KMnO4 should be used to obtain the KMnO needed? KMnO4, q.s. Distilled water, a.d. 1000 mL Sig: 2 teaspoons diluted to 500 mL yield a 1:5000 solution (A) 267.0 mL (B) 133.0 mL (C) 26.7 mL (D) 13.3 mL 98. The formula for Ringer’s solution follows. How much sodium chloride is needed to make 120 mL? Rx sodium chloride 8.60 g Potassium chloride 0.30 g Calcium chloride 0.33 g Water for injection, q.s. a.d. 1000 mL (A) 120.00 g (B) 1.03 g (C) 0.12 g (D) 103.00 g 99. How many grams of talc should be added to 1 lb of a powder containing 20 g of zinc undecylenate per 100 g to reduce the concentration of zinc undecylenate to 3%? (A) 3026.7 g (B) 2572.7 g (C) 17.0 g (D) 257.0 g 100. How many milliliters of a 0.9% aqueous solution can be made from 20.0 g of sodium chloride? (A) 2222 mL (B) 100 mL (C) 222 mL (D) 122 mL...