Chap - Chapters 21-22 practice reactions PDF

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Chapters 21-22 practice reactions...

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Chem. 12B

Chapter 21-22 Rxn Review

Rxn Review Chapter 21 Ammonium Salt Formation NH2

HCl

+ NH3Cl-

Amines by Alkylation H N

+ N

Br

NH2

Br-

N

Primary Amines by Nitriles I

1a) NaCN 2a) LiAlH4 b) H3O+

Primary Amine by Azides Br

NH2

NaN3

N

DMSO

N + N-

1a) LiAlH4 b) H3O+

Gabriel Synthesis O

1a) K2CO3 b) NH

Reductive Amination

Br

NH2

c) H2SO4 d) NaOH

O

NH3, NaBH3CN, H2O

O

Amines by reduction ofAmides O

1a) LiAlH4 N

b) H3O+

N

Hoffman Elimination CH3I K2CO3

Ag2O

+ IN

NH2

Ester by diazomethane O OH CH2NH2 O

Benzyl Radical Halogenation Br O

N2

Br2 light

NH2

NH2

Chapter 22 Cl

Nucleophilic Aromatic Substitution OH NO2

NO2 NaOH NO2

NO2

Benzyne Synthesis Br NaNH2, NH3 (l)

NH2

NH3

-NaCl

Phenols by Sulfonate Anions (SNAr)

-

OH

SO3 Na+ 1a) NaOH, Heat b) H2SO4

Practice Problems

NH2

+ NH 3Cl-

HCl

NH2

Br

+ N

Br+ others

1a) NaCN I

2a) LiAlH4 b) H3O+ 1. NaN3 Br

DMSO 2a) LiAlH4 b) H3O+

NH2

NH2

O

1a) K2CO3 b) Br

NH

NH2

c) H2SO4 d) NaOH

O NH2

O NH3, NaBH3CN, H2O O

1a) LiAlH4 N

N

b) H3O+

1. CH3I K2CO3 NH2

2. Ag2O O

OH

CH2N2

N2

O

O

Br Br2 light

OH

Cl

NO2

NO2 NaOH

NO2

NO2

Br NaNH2, NH3 (l) -NaBr

-

SO3

OH Na+ 1a) NaOH, Heat b) H2SO4...