Chapter 6 Skills - PDF

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Chapter 6 Skills

Knowledge - Level 1 know the terminology: nucleophile / electrophile (electron-pair donor / acceptor) endothermic / exothermic (absorbs / releases heat energy) regiochemistry / regioselectivity stereochemistry / stereoselectivity syn / anti additions oxidation / reduction reactions know the rules: Markovnikov Rule for addition to double bonds

Concepts - Level 2 recognize that the Markovnikov Rule is based on carbocation stability (more highly substituted carbocations are favored)

Applications - Level 3 use the Markovnikov Rule to predict addition products write or recognize specific instances of the reactions of alkenes: addition of HX addition of water addition of halogen (anti) addition of hydrogen (syn) oxymercuration/reduction (to an alcohol) hydroboration/oxidation (to an alcohol) oxidative addition (to a diol) oxidative cleavage (by ozone)

Analytical Skills - Level 4 write mechanisms for any of the above reactions, specifically illustrating any intermediates, regiochemistry or stereochemistry propose possible reaction mechanisms for a given reaction propose a possible transition state structure for a given reaction create a reaction energy diagram for a given reaction

Synthetic Skills - Level 5 use an appropriate reaction or sequence of reactions to create a target molecule...