Drug Study Format and Sample PDF

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Description

Drug name

Classification

Mechanism of action

Generic Name

Indication

Contraindication

Adverse reaction

Nursing responsibilities Before

Brand Name

During Actual dosage, route, frequency

After

Source :

Drug study format

Drug study sample Drug name

Generic Name Hydrocortisone

Brand Name Hydrocortone

Actual dosage, route, frequency

Classification

Corticosteroid

Mechanism of action

Indication

Enters target cells and binds to cytoplasmic receptor; initiates many complex reactions that are responsible for its anti-inflammatory, immunosuppressive (glucocorticoid), and saltretaining (mineralocorticoid) actions. Some actions may be undesirable, depending on drug use.

-Replacement therapy in adrenal cortical insufficiency - Allergic states – severe or incapacitating allergic conditions - Hematologic disorders - Ulcerative colitis

Contraindication

Adverse reaction

Hypersensitivity to drug

CNS: Vertigo, headache, paresthesias, insomnia, seizures, psychosis

Untreated serious infections (except tuberculous meningitis or septic shock)

CV: Hypotension, shock, HPN and heart failure secondary to fluid retention, thromboembolism, thrombophlebitis, fat embolism, cardiac arrhythmias

Idiopathic thrombocytopenic purpura Intrathecal administration (injection)

Dermatologic: Thin, fragile skin, petechiae, ecchymoses, purpura, striae, subcutaneous fat atrophy

Documented hypersensitivity Administration of live attenuated vaccines is contraindicated in patients receiving immunosuppressive doses of the drug

Endocrine: Amenorrhea, irregular mens, growth retardation, decreased carbohydrate tolerance and DM, cushingoid state, HPA suppression systemic , hyperglycemia

EENT: Cataracts, glaucoma, increased IOP

100mg, q6 IVTT

GI: Peptic or esophageal ulcer, pancreatitis, abdominal distention, nausea, vomiting, increased appetite and weight gain

Nursing responsibilities

Before: - You should not use this medication if you are allergic to hydrocortisone, or if you have a fungal infection anywhere in your body. - tell your doctor about all of your medical conditions, and about all other medicines you are using.

- Do not give live vaccines with immunosuppressive doses of hydrocortisone. During: - Do not give IM injections if patient has thrombocytopenic purpura. - Taper doses when discontinuing high-dose or long-term therapy. After: - Monitor client for at least 30 minutes.

Hematologic: Na and fluid retention, hypocalcemia, increased blood sugar, increased serum cholesterol, decreased T3 and T4 levels

- Educate client on the side effects of the medication and what to expect.

Hypersensitivity: Anaphylactoid or hypersensitivity reactions

- Instruct client to report pain at injection site.

Musculoskeletal: Muscle weakness, steroid myopathy and loss of muscle mass, osteoporosis, spontaneous fractures Other: Immunosuppression, aggravation or masking of infections, impaired wound healing

- Instruct client to take drug exactly as prescribed. -Carry an ID card or wear a medical alert bracelet stating that you are taking a steroid...