Gastrointestinal Physiology Multiple Choice Practice Questions PDF

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Practice exam questions for Gastrointestinal Module. Produced by myself from coursework and is in no way affiliated with the university....

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MPharm Year 2 Gastrointestinal Tract Example MCQ’s 1. Which tissue layer provides for primary digestive motility? a) Mucosa b) Submucosa c) Mesentery (a fold of tissue that attaches organs to the body wall) d) Muscularis Mucosa 2. What occurs during swallowing? a) All the processes of Deglutition are under voluntary control. b) The vocal folds are relaxed allowing the food to travel down the oesophagus c) The swallowing centre located within the medulla oblongata inhibits the medullary respiratory centre d) The food bolus travels down the oesophagus due to gravity 3. Amylase secreted by the salivary glands into the oral cavity starts the digestion of: a) Proteins b) Lipids c) Starch d) Amino acids 4. Where does the production of bile occur? a) Gallbladder b) Liver c) Pancreas d) Hepatic Ducts

5. Select the true statement regarding the control of gastric secretion: a) Gastric acid is secreted by parietal cells of the gastric glands in response to hormonal stimulation. b) Most of the secretion of acid and pepsinogen occurs during the intestinal phase. c) Gastric secretion does not begin until food enters the stomach. d) Secretin secreted by the duodenum stimulates gastric secretion.

6. The Myenteric plexus lies between the longitudinal and circular smooth muscle layers of the gut wall.

a) True b) False

7. Intrinsic factor is required for the intestinal absorption of _________ in the upper ileum: a) Vitamin D b) Amino Acid c) Vitamin B12 d) None of the above

8. Regarding pancreatic secretion: a) Pancreatic secretion is inhibited by gastrin secreted by the G cells of the antrum b) Pancreatic acinar cells contain trypsin c) Cholecystokinin inhibits secretion from the exocrine pancreas. d) The introduction of acid into the duodenum stimulates pancreatic secretion.

9. Cimetidine and a calcium-containing antacid preparation administered in an appropriate dosage regimen for treating peptic ulcer differ in that:

a) Only the calcium-containing antacid may increase gastric acid secretion. b) Only cimetidine is likely to cause an increase in urinary pH. c) Only cimetidine is likely to produce a laxative effect.

d) Only cimetidine can prevent the rise in gastric pH after the consumption of a meal.

10. Which of the following statements about fat and fat digestion/absorption is true? a) Fat soluble vitamins are incorporated into mixed micelles and absorbed directly across the microvillus cell membrane b) Triglycerides are resynthesized from fatty acids and monoglyceride in the intestinal epithelial cell and are exported directly into the portal circulation c) Pancreatic lipase functions best at a pH of 3 d) None of the above

11. Loperamide is like morphine in that a single therapeutic dose of each produces: a) Slowed transit of intestinal contents b) More rapid gastric emptying c)

Increased colonic secretion of chloride ion

d) None of the above

12. Every mucosa consists of: a) A simple epithelium b) A surface epithelium together with associated glands c) A surface epithelium layer, with or without glands with an underlying layer of loose connective tissue. d) A surface epithelium layer, with or without lands together with an underlying connective tissue and a layer of smooth muscle.

13. The layer of tissue beneath the mucosa is called the: a) Muscularis externa b) Circular Muscle c) Serosa d) Submucosa

14. In most regions of the GI tract, smooth muscle fibres of the muscularis are arranged into: a) Circular muscle (inner) followed by longitudinal muscle (outer) b) Longitudinal muscle (inner) followed by Circular muscle (outer) c) Circular and Longitudinal muscle whose relative position varies at different regions d) Circular muscle (inner) followed by Longitudinal muscle and Serosa (outer)

15. For an organ lying within a body cavity, the tissue which is farthest away from the inner core or lumen of the organ is called the: a) Muscularis externa b) Serosa c) Mucosa d) Myenteric Plexus

16. Submucosal glands occur in the submucosa of the ________ and they also occur in the _________. a) Oesophagus and ileum

b) Stomach and Duodenum c) Stomach and ileum d) Oesophagus and Duodenum

17. Folds in the mucosa of the stomach are called _________ which allows the surface area to _________. a) Crypt, Increase b) Rugae, Increase c) Rugae, Decrease d) Crypt, Decrease

18. Simple tubular glands within the mucosa of the small or large intestine are called intestinal: a) Villi b) Peyer’s Patch c) Crypt d) Pits

19. Choose the best description of the duodenum. a) Mucosa with crypts and villi; epithelium with scattered goblet cells; lamina propria with occasional lymph nodules; submucosa unspecialized. b) Mucosa with crypts but no villi; epithelium with scattered goblet cells; lamina propria with occasional lymph nodules; submucosa unspecialized.

c)

Mucosa with both crypts and villi; epithelium with scattered goblet cells; lamina propria with occasional lymph nodules; submucosa with mucous glands.

d) Mucosa with both crypts and villi; epithelium with scattered goblet cells; lamina propria packed with mucous glands; submucosa with numerous lymph nodules

20. In which region of the GI tract is the longitudinal muscle of the muscularis arranged into distinct longitudinal bundles? a) Duodenum b) Jejunum c) Ileum d) Colon

21. The parotid gland is a: a) Serous gland, secreting a watery solution of enzymes and immunoglobulins but not mucus. b) Mucous gland, secreting mucus but not digestive enzymes. c) Mixed gland, producing both serous and mucous secretions.

22. The submandibular and sublingual glands are: a) Mucosa glands, secreting mucus but not digestive enzymes b) Serous glands, secreting a watery solution of enzymes and immunoglobulins but not mucus. c) Mixed glands producing both serous and mucous secretions.

23. Mucosa surface cell secretes mucous which provides a physical barrier between ______________ and __________.

a) Mucosa and Epithelium b) Lymph Vessel and lamina Propria c) Mucosa and Lumen d) Lumen and Epithelium

24. The role of Chief cell is to: a) Secretes hydrogen ions and chloride ions into lumen and are responsible for maintaining the acidic pH b) Secrete pepsin which digests proteins. c) Secretes Gastrin which stimulates gastric acid secretion d) Secretes pepsinogen.

25. The role of parietal cells is to: a) Secretes hydrogen ions and chloride ions into lumen and are responsible for maintaining the acidic pH b) alkaline mucous for shielding the epithelium from hydrochloric acid c) Secretes histamine which stimulates gastric acid secretion d) Secretes gastric lipase

1. D 2. C 3. C 4. B - Assists with fat digestion and absorption in the gut. 5. A - Gastric secretion is stimulated by gastrin released from G cells of the gastric glands. Gastric secretion begins with the cephalic phase which is associated with the sight and smell of food. Secretin inhibits gastric secretion. 6. A - It forms part of the enteric nervous system. It plays an important role in the regulation of motility in the GI tract. 7. C 8. D - The G cells of the antrum stimulate enzyme secretion by the pancreas. The pancreatic acinar cells contain trypsinogen, which is converted to trypsin in the small intestine by enteropeptidase. Cholecystokinin stimulates enzyme secretion by the pancreatic acinar cells. Acid in contact with the duodenal wall causes the secretion of secretin, which stimulates a copious alkaline secretion by the cells of the pancreatic ducts. 9. A 10. A 11. A 12. C 13. D 14. A 15. B 16. D 17. B 18. C 19. C 20. D 21. A 22. C 23. D 24. B 25. A...