Multiple choice questions for practice with answers PDF

Preview

Summary

Additional MCQ for practiceWhich of the following is CORRECT?1Insulin is co-secreted with C peptide 2 Insulin secretion is stimulated by the sympathetic system 3 Amylin is another pancreatic hormone co-secreted with glucagon 4 Insulin secretion is reduced by glucagon-like peptide 5 C peptide has no ...

Description

Additional MCQ for practice Which of the following is CORRECT? 1Insulin is co-secreted with C peptide 2 Insulin secretion is stimulated by the sympathetic system 3 Amylin is another pancreatic hormone co-secreted with glucagon 4 Insulin secretion is reduced by glucagon-like peptide 5 C peptide has no biological effects

Generally, following an ingestion of a drink containing glucose: 1 Less insulin will be secreted than it will be following an iv administration of the same amount of glucose 2 Only the cephalic phase of insulin secretion is activated 3 Insulin secretion will ensue due to the activation of the sulfonurea-dependent potassium channel of the beta pancreatic cell 4 The gastrointestinal phase cannot be activated 5 More insulin will be secreted than it will be following an iv administration of the same amount of glucose

Which of the following statement about the sulphonylureas in CORRECT? 1 Are a class of insulin secretagogues 2 Can reduce appetite and weight gain 3 Are particularly efficient at reducing the post-prandial peak of glucose 4 Are first choice treatment for T2D in all cases 5Inactivated the voltage dependent potassium channel found on the bera cells Which of the following statements about the biguanides in INCORRECT? 1 They are a class of insulin secretagogues 2 The are usually prescribed as second-choice drug for T2 diabetes 3 They increase insulin receptor resistance 4 They are recommended for both type1 and type2 5 All statements are incorrect Which of the following statements about Glucagon-like peptides is CORRECT? 1 2 3 4 5

They are co-secreted with glucagon They are pituitary hormones Potentiate insulin release, particularly in fasting conditions Can attenuate the post prandial peak of glucose Their plasmatic half-life is between 15-20 min

Which of the following statements about Sodium-glucose cotransporter 2 (SGLT2) inhibitors (eg Dapagliflozin) is CORRECT? 1 stimulate glucose-induced insulin release 2 they directly interact with the beta cells to reduce insulin resitance 3 increase glucose reabsorption by the kidneys 4 inhibits sodium-glucose cotransporter in the renal proximal tubule 5 they can cause hypoglycaemia in fasting condition

Which of the following statements about benzodiazepine is CORRECT 1 2 3 4 5

Inhibit the sedative effects of alcohol Should only be used as hypnotics for a maximum of 2 years Are competitive GABAA receptor agonist Facilitates the opening of a chloride channel in the presence of GABA They can be used for the long-term therapy of anxiety disorders

Which one of the following is a present experimental drug for the treatment of resistant major depression 1 2 3 4 5

Salbutamol Heroin LSD Paroxetine es-ketamine

A drug has a PKi of 8 and 7, and 4 for the serotonin and noradrelanine and dopamine neuronal transporters, respectively, as well as a PKi of 4 for the muscarinic receptor. It has no known significant affinity for other receptors. This means that this drug can be 1 2 3 4 5

has the pharmacological profile of a third-generation antidepressant Has the pharmacological profile of a SSRI Has the pharmacological profile of a SNRI Has the pharmacological profile of a triple uptake inhibitor Has the pharmacological profile of a tricyclic antidepressant

Which one of the following statement related monoamine oxidase inhibitor is CORRECT? 1 2 3 4 5

they all can inhibit indifferently Monoamine oxidase A and Monoamine oxidase B they target a mitochondrial enzyme their therapeutic use is for major depression only targeting only mono amine oxidase B is therapeutically relevant they stimulate the synthesis of all monoamines

Which one of the following drugs does not interact with GABA receptors? 1 Baclofen 2 Pregabalin 3 Diazepam 4 z-drugs 5 picrotoxin

Which of the following statements about SSRI antidepressants is not true? 1 are efficient in all forms of anxiety disorders 2 may not need always to be prescribed for anxiety disorders 3 have a longer onset of action than for treating depression 4 need to be administered with benzodiazepine as adjunct therapy 5 can worsen anxiety symptoms, in particular, at the beginning of treatment

Which of the following statements about blood TSH levels is CORRECT 1 are generally very low during hypothyroidism 2. are generally very high in individuals suffering from Grave’s disease 3. are usually very high in individuals with iodine deficiency 4. are very low in individual suffering from Hasmimoto’s disease 5. are high in patients suffering from thyroid nodules

During the early stage of the follicular phase: 1. 2. 3. 4. 5.

LH levels dramatically increase A graafian follicle develops FSH levels slightly increase Progesterone is secreted massively Secretion of G-mucus is stimulated

Which of the following statement related to Iodine deficiency during pregnancy is UNCORRECT? 1. 2. 3. 4. 5.

Can be responsible for severe mental retardation of the future child Can cause still birth Can cause some form of hypothyroidism Can be related to low level of TRH release Can be related to hyperstimulation of TSH receptors

Which of the following statement about Progestogens is CORRECT? 1. 2. 3. 4. 5.

Are mainly synthesised by the Graffian’s follicles Are mainly secreted during the follicle phase Are mainly secreted by the corpus luteum Reduce the secretion of the G-mucus High concentration of progestogen can trigger ovulation

Which of the following statement about Thyroid hormone receptors is CORRECT? 1. Are mainly membrane receptors 2. Once stimulated, they recognise and bind to a specific stretch of DNA on each target gene 3. Are nuclear receptors 4. Are overactivated in Hashimoto’s disease 5. Stimulate gene transcription only

Which of the following statement about Hashimoto’s disease is CORRECT? 1. Is a rare form of hypothyroidism 2. Can be treated with the thiouracil drugs 3. Is a form of hyperthyroidism caused by an autoimmune disease 4. Can be treated with iodine (lugol) 5. Is associated with high levels of TSH secretion...