HW Thermodynamics Problem Set PDF

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Thermodynamics Problem Set to be turned in online. Both Questions and Answers provided...

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Fundamentals of Biochemistry, Fall 2017 Thermodynamics Problem Set

Due Online: 1PM Wednesday September 6, 2017 9abfbba032358db2ac901a036e0cf59b.docx

Below are the questions to the online homework assignment “ACMS5003_ThermoPS_Online_2017”. Use this sheet to work through the problems and record your answers before completing the online assignment. During the workshop, you may be called upon to show the class how you solved the problem. Carefully record your notes on this sheet so you are prepared to demonstrate your understanding. This online homework is not timed. You will have 5 attempts to complete/submit your answers online. Only your highest score will count. The online assignment on Bb must be submitted no later than Wednesday Septebmer 6 at 1PM. Use the constants provided in the homework for your calculations, round numerical values to the number of significant figures indicated in the questions. When entering scientific notation, use the "^" sign to indicate power with no spacing between characters. Example: If answer is 2x104 , then enter 2x10^4cientific notation

1. (0.1 points) From the information given, which of the following equations can be used to calculate the numerical value of the equilibrium constant (Keq) for the reaction below? ∆G’o = -7.3 kcal/mole

ATP + H2O  ADP + Pi A. B. C. D. E.

∆G=∆H-T∆S ∆Go=1.36kcal/mol*log(Keq) ∆G=∆Go +1.36kcal/mol*log Qc [ADP]*[Pi]/[ATP]*[H2O] ∆Go=-1.36kcal/mol*log(Keq)

2. (0.1 points) The equilibrium constant (Keq) for the reaction below is _ 2.33 x 105_ (numerical value)__M___(units). (Round numerical values to three significant figures) ATP + H2O  ADP + Pi

∆G’o = -7.3 kcal/mole

3. (0.1 points) When ATP = 3mM, ADP=2.2mM, and Pi=12.1 mM, the reaction quotient (Qc) for the reaction below is _8.87x10-3_ (numerical value)___M__(units). (Round numerical values to three significant figures)

ATP + H2O  ADP + Pi

∆G’o = -7.3 kcal/mole

4. (0.1 points) When ATP = 3mM, ADP=2.2mM, and Pi=12.1 mM, the overall free energy (∆G) for the reaction is _-10.1_ (kcal/mole). (Round numerical values to three significant figures) ATP + H2O  ADP + Pi

∆G’o = -7.3 kcal/mole

5. (0.05 points) When ATP = 3mM, ADP=2.2mM, and Pi=12.1 mM, the reaction quotient (Qc) is _less than_ (equal to, less than, greater than) the Keq and the reaction below will proceed to the _right_(left, right, equally in either direction) ATP + H2O  ADP + Pi

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∆G’o = -7.3 kcal/mole

Fundamentals of Biochemistry, Fall 2017 Thermodynamics Problem Set

Due Online: 1PM Wednesday September 6, 2017 9abfbba032358db2ac901a036e0cf59b.docx

6. (0.1 points) For the reaction below, condition __1_ (1, 2, 3, 4 or 5) proceeds furthest to the right. ∆G’o = -7.3 kcal/mole

ATP + H2O  ADP + Pi T= 25oC

1.(mM)

2.(mM)

3.(mM)

4.(mM)

5.(mM)

ATP

5

3

1

0.2

5

ADP

0.2

2.2

4.2

5.0

25

Pi

10

12.1

14.1

14.9

10

7. (0.05 points) Which of the following equations can be used to predict whether a reaction will proceed to the left under non-standard (non-equilibrium) conditions? A.

[C]c[ D]d Q c  ai bi [ A ]i [B]i

B. Qc = Keq C.

[C]c [D] deq K eq  eq [A]aeq[B] beq

D. Qc > Keq E. ∆Go’=-1.36kcal/mol*log10(Keq) F. Qc < Keq 8. (0.1 points) If ADP and Pi were 25 and 10 mM respectively, the following reaction will proceed to the left when the concentration of ATP is __...