Lab Safety Manual - Univeristy of Washington PDF

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LABORATORY SAFETY MANUAL NOVEMBER 2020/EDITION

Environmental Health and Safety Department University of Washington Box 354400 Seattle, WA 98195-4400 Phone: 206.543.7262 FAX: 206.543.3351 www.ehs.washington.edu

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TABLE OF CONTENTS Emergency Information...................................................................................................................................11 Laboratory-Specific Information ....................................................................................................................12 SECTION 1: LABORATORY RESPONSIBILITIES ...............................................................................................15 A. Purpose…………................................................................................................................................. 16 1.Chemical Hygiene Plan (CHP)...............................................................................................................16 2.Regulations Pertaining to the Chemical Hygiene Plan .....................................................................16 3. Chemical Hygiene Plan Accessibility ..................................................................................................17 4. Other Plans and References ...............................................................................................................17 5. Applicability to Students ......................................................................................................................17 B. Scope And Application ........................................................................................................................ 18 1. Chemical Laboratory ............................................................................................................................18 2. Chemical and Non-Chemical Hazards ...............................................................................................18 C. Responsibilities..19 1. Responsible Party and Chemical Hygiene Officer ............................................................................19 2. Dean, Department Chair and Director...............................................................................................24 3. Employees/Students.............................................................................................................................25 4. Environmental Health and Safety Department ................................................................................25 5. UW Chemical Hygiene Officer (UW CHO) ..........................................................................................26 6. Institutional Chemical and Physical Safety Committee (ICAPS)......................................................26 SECTION 2 - CHEMICAL MANAGEMENT ........................................................................................................27 a.Basic Laboratory Safety Practices ........................................................................................................ 29 1.Working Alone........................................................................................................................................29 2.Prevent Chemical Exposure .................................................................................................................29 3.Washing Hands ......................................................................................................................................30 4.Food and Drink ......................................................................................................................................30 5.Access to Emergency Exits and Equipment .......................................................................................30 6.Laboratory Signs ....................................................................................................................................30 7.Housekeeping. .......................................................................................................................................31 8.Sharps Safety.. .......................................................................................................................................31 B.Chemical Inventory And The Safety Data Sheet (SDS)........................................................................ 31

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1.Access to MyChem ................................................................................................................................32 2.Conducting Your Chemical Inventory .................................................................................................32 3.Safety Data Sheet (SDS) ........................................................................................................................33 C. Chemical Procurement ........................................................................................................................ 33 1.Hazardous Chemicals ...........................................................................................................................33 2.Pharmaceuticals ....................................................................................................................................33 3.DEA Controlled Substances..................................................................................................................34 4.Non-Denatured Ethyl Alcohol ..............................................................................................................34 5.Radioactive Materials ............................................................................................................................34 6.Highly Dangerous Materials .................................................................................................................34 7.Compressed Gas Cylinder Procurement ............................................................................................34 8.Chemical Exchange ...............................................................................................................................35 9.Additional exceptions ...........................................................................................................................35 D.Chemical Storage ................................................................................................................................. 35 1.Evaluate Chemical Hazards for Storage .............................................................................................35 2. Chemical Storage Practices .................................................................................................................36 3. Chemical Storage Quantity Limits ......................................................................................................39 E.Chemical Labeling ................................................................................................................................ 39 1.Original Container .................................................................................................................................39 2.Labeling Stock / Working Solutions .....................................................................................................40 F.Transporting Chemicals ........................................................................................................................ 42 1.Transporting between Floors and Buildings on Campus.................................................................42 2.Transporting Chemicals off Campus...................................................................................................43 3.Receiving Chemical Shipments ............................................................................................................43 G.Special Chemical Hazards ................................................................................................................... 44 1.Highly Dangerous Chemicals ...............................................................................................................44 2.Particularly Hazardous Substances.....................................................................................................44 3.Reactive Chemicals ................................................................................................................................45 2.Potentially Explosive Chemicals...........................................................................................................47 3.Highly Toxic Substances .......................................................................................................................50 4.Carcinogens and Reproductive Hazards ............................................................................................51 5.Sensitizing or Allergenic Chemicals .....................................................................................................53 6.Synthesized Chemicals..........................................................................................................................53

Environmental Health & Safety Department | www.ehs.washington.edu | LABORATORY SAFETY MANUAL

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7.Compressed Gases, Gas Cylinders and Liquid Cryogen Containers Compressed .......................54 8.Flammable and Combustible Liquids .................................................................................................57 9.Homeland Security Chemicals of Interest ..........................................................................................59 10. Process Safety for Highly Hazardous Chemicals .............................................................................61 H. Regulated Hazardous Chemicals listed under the WAC Washington Vertical Standard..................... 61 SECTION 3: CHEMICAL WASTE MANAGEMENT ............................................................................................63 A.Hazardous Chemical Waste Responsibilities ....................................................................................... 65 1.Laboratory Workers...............................................................................................................................65 2.UW EH&S Environmental Programs....................................................................................................65 B.What Qualifies as Hazardous Waste? .................................................................................................65 1.Flammable/Ignitable .............................................................................................................................65 2.Corrosive………. .......................................................................................................................................66 3.Reactive………… .......................................................................................................................................66 4.Toxic……………….......................................................................................................................................66 5.Persistent……… .......................................................................................................................................68 6. Carcinogenic….......................................................................................................................................68 7. Waste Evaluation Request ...................................................................................................................69 C.Hazardous Waste Accumulation Rules ................................................................................................ 69 1.Appropriate Containers ........................................................................................................................69 2.Hazardous Waste Labels.......................................................................................................................69 3.Segregation…….......................................................................................................................................70 4.Accumulation Volume Limits ...............................................................................................................70 5. Large Containers (Drums) ...................................................................................................................71 6. Inherently Waste-like Chemicals ........................................................................................................71 D.Hazrdous Waste Collection Requests .................................................................................................. 71 1. Hazardous Waste Collection Overview..............................................................................................71 2. Collection Requests – One-Time.........................................................................................................71 3. Routine Collection Requests ...............................................................................................................71 4. Waste Cleanouts ...................................................................................................................................72 5. What Happens to Hazardous Waste? ................................................................................................72 E.Trash Disposal…… .............................................................................................................................. 72 1.Trash Disposal of Chemicals ................................................................................................................73 2. Trash Disposal of Empty Chemical Containers.................................................................................73

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3. Trash Disposal of Contaminated Items .............................................................................................74 F.Discharges To The Sanitary Sewer ...................................................................................................... 74 1.King County Local Sewer Discharge Limits ........................................................................................74 2.Outside King County .............................................................................................................................75 3.Treating Hazardous Wastes .................................................................................................................75 4.Soaps, Bleach and Acetone ..................................................................................................................75 5.Scintillation Fluids ..................................................................................................................................75 6.Dilution Prohibition ...............................................................................................................................75 G.Chemical Wastes Of Particular Concern .............................................................................................. 76 1.Unknown Chemicals..............................................................................................................................76 2.Potentially Explosive Wastes ................................................................................................................76 3.Peroxide-Forming Chemicals ...............................................................................................................76 4.Picric Acid and Other Polynitroaromatic Compounds ......................................................................76 5.Legacy Chemicals...................................................................................................................................77 H.Hazardous Waste Minimization ............................................................................................................ 77 1.Treatment and Recycling in the Laboratory.......................................................................................77 2.Hazardous Materials Recycling ............................................................................................................77 I.Solid Waste and Recycling .................................................................................................................... 77 1.Paper and Cardboard ...........................................................................................................................77 2.Plastic and Glass ....................................................................................................................................78 3.Packaging Materials ..............................................................................................................................78 4.Printer Cartridges ..................................................................................................................................78 5.Batteries……….. .......................................................................................................................................78 6.Metallic Lead… .......................................................................................................................................78 J.Sharps, Lab Glass And Plastic .............................................................................................................. 78 1.Sharps…………… ......................................................................................................................................78 2.Trace Chemo Sharps .............................................................................................................................79 3.Biohazardous Glass and Plastic Items ................................................................................................79 4.Lab Glass………........................................................................................................................................80 K.Infectious Or Biological Waste.............................................................................................................. 80 L.Radioactive Waste ................................................................................................................................ 80 M.Mixed Waste…… ................................................................................................................................. 80 N.Liquid Scintillation Cocktails ................................................................................................................. 81 O.Animals And Animal By-Products ........................................................................................................ 81

Environmental Health & Safety Department | www.ehs.washington.edu | LABORATORY SAFETY MANUAL

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1.Contaminated Animals and Animal By-Products ..............................................................................81 2.Non-Contaminated Animals and Animal By-Products .....................................................................81 P.Gas Cylinders……................................................................................................................................ 81 SECTION 4 - LABORATORY EQUIPMENT AND FACILITIES............................................................................83 A.Emergency Eyewashes And Showers .................................................................................................. 85 1.Eyewash Stations ...................................................................................................................................85 2.Safety Showers.......................................................................................................................................85 ...