Neuroscience Exam 2 Content PDF

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Summary

Lecture notes from professor Deyo's Intro to Neuroscience course for exam 2 content. These contain notes from chapters 3 through 5....

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Basal ganglia- little girl walking

D2 pathway

Can’t walk straight, losing balance and has a wider stance with over correction

Inability to control the termination of movement-

Produce high amount Become extremely at Huntington average 5

Type 1- Caucasian’s 2- African american

Normal: 2 -chromosome 4 -autosomal dominant -CAG repeat error (cytosine-adenine-guanine) codes for the amino acid glutamine and the resulting production of the Huntington’s disease -number of errors determines age of onset and severity of the disease and age of death 5 year old died around age 7–> 200 errors 40 year old woman —> 100 errors Cells in D2 pathway die off and cells in D1 pathway Overcompensate for the D2 pathway and may die No treatment

-affected his right side of the body -tremors -no facts, expression -didn’t blink -slower movement -couldn’t bring his knee up very high -slow gettin up, hand still tremor -walking down the hall needs to hold wall to turn around and right arm has a tremor

Monoamine oxidate B- enzyme,es in human to prevent high effect? A

- organophosphate

MPTP core Si il t h

i...