NMR tutorial PDF

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Tutorial based on NMR spectroscopy...

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Introduction to Spectroscopy tutorial sheet: NMR spectroscopy 1. Sketch and assign the 1H and 19F NMR spectra for compounds A-D shown below, indicating integrations, multiplicities and coupling constants. Assume coupling occurs only through 3 bonds or fewer and that 1H (I=1/2) and 19F (I=1/2) are 100% abundant; all other nuclei are NMR inactive.]

CHF2 O

CF3

O

A

2.

F

O

B

C

D

Benzene-1,4-diboronic acid, benzene-1,2-diboronic acid and benzene-1,3-diboronic acid are isomers with the molecular formula C6H8B2O4. I.

Sketch the 1H NMR spectra of these isomers.

[You may assume coupling occurs only through 3 bonds or fewer and that 1H, I=1/2, 100% abundant; all other nuclei are NMR inactive.]

3.

Six possible isomers with the molecular formula C4H8O2 are shown below. Use the 1H and 13C{1H} NMR data below to identify three of these isomers.

O

O

O

O

O

O O

E

O

F

G

N.B.: 1H NMR spectrum shows a singlet, quartet and a triplet in a 3:2:3 ratio

OH

OH

O

O

H

I

J

N.B.: 1H NMR spectrum shows a singlet, a septet and a doublet in a 1:1:6 ratio

N.B.: 1H NMR spectrum shows a single, multiplet, and quintet in a 1:2:1 ratio

4.

Sketch and annotate the 19F and 31P NMR spectra for the compound shown below. [Assume coupling occurs only through 3 bonds or fewer and that 1H, 19F, and 31 P are I=1/2 and 100% abundant; all other nuclei are NMR inactive.]

F 3C PH F 3C...