NUR2474 Module 6 Quiz Review PDF

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Pharmacology Module Quiz Review...

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NUR2474 Pharmacology Module 6 Quiz Review Quiz tips: There are many negatively worded questions this time around. Please pay attention to the wording. 1. Cholestyramine (mechanism of action, indications, side and adverse effects, administration, monitofring, food/drug interactions) a. Bile-Acid Sequestrant b. Mechanism of action i. May decrease uptake of fat-soluble vitamins ii. Does not significantly reduce the absorption of stains, warfarin, digoxin, and most other drugs studied. iii. Reduces LDL cholesterol, Increases VLDL levels in some patients iv. Increased LDL receptors on hepatocytes v. Prevents reabsorption of bile acids vi. Trap cholesterol in bile salts and make you secrete it vii. Form insoluble complexes with bile salts, prevents reabsorption of bile acids, therefore accelerating their excretion. viii. Do not neutralize stomach acid, but they line your stomach creating a barrier. c. Indications i. Reduces LDL cholesterol (in conjunction with modified diet and exercise d. Side/Adverse Effects i. GI effects 1. Constipation (common) a. Educate about increasing fluids and fiber ii. Hepatotoxicity e. Administration i. Take medications that may interact at least one hour before taking bilesequestrants or 4 hours after. ii. Come as a powder and need to be mixed in a drink 1. Swallowing dry may cause esophageal irritation and impaction. iii. Often combined with statins iv. Dosage range: 4-24 g/day v. Cholesterol drugs should only be given when modifiable efforts have failed. f. Monitoring i. Cholesterol levels 1. Once patient is started on pills, redraw cholesterol ii. Labs 1. Lipid panel a. Normal cholesterol level: i....