Pharmacokinetics and pharmacodynamics PDF

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Summary

Pharmacokinetics and pharmacodynamicspharmacokinetics*The effect of the body on the drug molecules when drugs are administered.*It involves: -Transport of drugs across cell membrane -Absorption of drugs -Distribution of drugs -Biotransformation of drugs -Excretion of drugsPharmacodynamicsPharmacolog...

Description

Pharmacokinetics and pharmacodynamics pharmacokinetics *The effect of the body on the drug molecules when drugs are administered. *It involves: -Transport of drugs across cell membrane -Absorption of drugs -Distribution of drugs -Biotransformation of drugs -Excretion of drugs

Pharmacodynamics Pharmacological effect of the drug molecules on the body

Receptor binding *A receptor- part of macromolecular complex in a living cell or living organisms with which the drug interact *A specific receptor-a receptor, if stimulated, leads to a specific pharmacological effects. *Affinity-a selective power of attraction between the drug molecule and the receptor *Agonist- a drug that stimulates a specific receptor to bring a certain pharmacological effect *Antagonist-a drug with affinity for but no intrinsic activity on the receptors...