PHR 4105 - Drugs and Infect Dis12016 PDF

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St. John’s University Jamaica, New York College of Pharmacy and Health Sciences Drugs and Infectious Diseases Syllabus Required Pharmacy Course

PHR 4105 Fall 2016 ( revised 10/4/2016)

Dr. Francis Schanne, Pathology Dr. Chul-Hoon Kwon, Medicinal Chemistry Dr. Vikas Dukhande, Pharmacology Dr. John Conry, Pharmacotherapy Dr. Joseph Etzel, Pharmacotherapy Dr. Yumin Lee, Pharmacotherapy Dr. Joseph Brocavich, Course Coordinator

A. Course Title:

PHR 4105 - Drugs and Infectious Diseases

B. Course Credit:

4 Semester Hours

C. Prerequisites:

All courses of the first three years, in particular, Infectious Disease and Clinical Immunology for Pharmacists.

D. Course Description:

This course is designed to instruct the student in the area of Infectious Disease. Teaching emphasis will be a sequential method of instruction relevant to specific disease states to incorporate the areas of pathophysiology, pharmacology, medicinal chemistry, therapeutics and self care therapies. This course will incorporate interdisciplinary instruction utilizing faculty from varied areas of expertise and experience.

E. Lecture Hours 1st hour x 15 weeks 2nd hour x 15 weeks 3rd hour x 15 weeks 4th hour x 15 weeks Total

Contact Hours Supplemental Assignments 15hrs 30hrs 15hrs 30hrs 15hrs 30hrs 15hrs 30hrs 60hrs +

120 hrs =

180 hrs

Supplementary assignments will include: assigned readings, review of previous didactic course materials, completion of patient case studies and pharmacy consults. F. Learning Objectives: The student will be able to: 1. Describe basic pathophysiologic events which occur in specific disease states amenable to pharmacologic intervention 2. Relate Chemical and Pharmacological drug categories to their use in specific disease states. 3. Describe the pharmaco-chemical basis of the mechanisms of drug action. 4. Select a drug dosage regimen for a particular beneficial and adverse reactions of drug therapy, distinguishing them from the clinical course of the disease state. 5. Provide treatment suggestions which obviate therapeutic ineffectiveness, drug interactions, adverse reactions or drug allergies by proposing alternative drug therapies and/or dosage or dosing interval adjustment for a particular patient.

G. Assessment (All exams will be given from 3:00 – 5:00 PM in Marillac Aud) Examination 1 (10/20) (Basic Science to 10/19) 20% Examination 2 (11/3) (Intro, CAP, UTIs, IMM) 40% Examination 3 (11/10) (Avascular, GI/STD, Skin HIV) 40% Recitation (integrated in exams 2 and 3) 10% Total 100% H. Units of Instruction Date 9/28 9/29 9/30 10/3 10/4 10/5 10/6 10/7 10/11 10/12 10/13 10/14 10/17 10/18 10/19 10/20 10/21 10/24 10/25 10/26 10/27 10/28 10/31 11/2 11/3 11/4

Topic Course Introduction/ Infectious Disease Pathology I Infectious Disease Pathology II Antibacterial Pharmacology I Antibacterial Pharmacology II Antibacterial Pharmacology III Medicinal Chemistry of Antimicrobials Medicinal Chemistry of Antimicrobials Medicinal Chemistry of Antimicrobials AntiTB and antiprotozoal Pharmacology Antifungal Pharmacology Antiviral Pharmacology (not HIV) Antiviral Pharmacology HIV Medicinal Chemistry of Antimicrobials Medicinal Chemistry of Antimicrobials Medicinal Chemistry of Antimicrobials basic science recitation Infectious Disease Pharmacotherapy Community Acquired Pneumonia (CAP) Immunizations Urinary Tract Infections (UTIs) Gastrointestinal infections/STDs Avascular Infections Recitation Integrated Exam I (Intro, CAP,Imm and UTIs) HIV Management HIV/ Skin Infections Recitation Integrated exam 2 (GI/STD, Avascular, Skin,HIV)

Faculty Dr. Brocavich/Dr. Schanne Dr. Schanne Dr. Dukhande Dr. Dukhande Dr. Dukhande Dr. Kwon Dr. Kwon Dr. Kwon Dr. Dukhande Dr. Dukhnade Dr. Dukhande Dr. Dukhande Dr. Kwon Dr. Kwon Dr. Kwon All Dr. Lee Dr. Etzel Dr. Etzel Dr. Etzel Dr. Lee Dr. Lee All Dr. Conry Dr. Conry All

I.

References

Required 1. Koda-Kimble MA, Young LY, Alldredge BK, et al. Applied Therapeutics : The Clinical Use of Drugs ; Lippincott Williams & Wilkins, MD (current edition) 2. Other texts from Anatomy and Physiology (PHS 3405/07), Pathophysiology (PHS3510), Introduction to Medicinal Chemistry (PHS 3508) and Pharmacology (PHS 3509) will be determined by PHS faculty from the third year. 3. Handbook of Nonprescription Drugs. American Pharmaceutical Association. Washington D.C. Current edition. Supplemental Additional specialized references/readings may be required at the discretion of the course’s faculty. Such requirements will be made available to students on the first day of the course....