Proliferative capacity of tissue PDF

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how the proliferative capacity of different tissues varies...

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Pr ol i f e r at i vec apac i t y Labi l et i s s ue  Ce l l sa r ec ons t a nt l ybe i ngl os ta ndmus tbec ont i nual l yr e pl a c edbyne wc e l l st ha tar ede r i ve d f r om t i s s ues t e mc e l l sandr a pi dl ypr ol i f e r a t i ngi mma t ur epr ogeni t or s . o Don’ te nt e rG0 o Ma t ur a t i onofs t e mc e l l sorpr ol i f e r a t i onofma t ur ec e l l st of or mt het i s s ue o Ti s s uec anr e gener a t ei fs t e mc e l lr e s er vei se nougha ndt i s s ues t r uc t ur ei si nt ac t  Exampl e s : o He ma t opoi e t i cc e l l s : c e l l soft hebl ood o Epi t he l i a lc e l l s :s ki n, GI T ,e t c .

St abl et i s s ue  Ar ema deupofc e l l st ha ta r enor mal l yi nt heG0s t a geoft hec e l lc yc l eandhe nc enot pr ol i f er a t i ng, butt he ya r ec a pa bl eofdi vi di ngi nr e s pons et oi nj ur yorl os soft i s s uemas s . o Qui e s c ent o Re e nt e rc e l lc yc l ef r om G0i fs t i mul a t e dbyal os sofc e l l s o Howe ver , hasal i mi t edc apac i t yt or e ge ner a t e( e x c ept i onoft hel i ve r )  Exampl e s : o Par e nc hymaofmos ts ol i dor ga ns( l i ve randki dne y) o Endot he l i a la nd. Smoot hmus c l ec e l l s , fibr obl a s t s...