PSA.12 NEW - Chapter 45 Objectives: The Immune System: Internal Defense PDF

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Chapter 45 Objectives: The Immune System: Internal Defense...

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Pre-Session Assignment (PSA) #12 Complete the vocabulary-matching sections and at least the first three objectives for each chapter. Doing so will prepare you for recitations and for the quizzes. You are highly encouraged to complete the rest of the objectives to keep you on track and so you can ask for clarification during recitation. All answers can be found in the textbook, even if a section has not yet been covered in lecture. Please print, complete, and bring to recitation. Chapter 45 Objectives: The Immune System: Internal Defense 1. Compare and contrast the human specific (adaptive) and nonspecific (innate) immune responses including for example the cells, secretions and processes involved in each (web helpful!) Adaptive immune response happens when you are exposed to an antigen either from a pathogen or if you received a vaccination. This is activated when the innate immune response is not enough to control whatever infection it is. T and B cells are activated to stop the infection. Nonspecific immune response will respond to any antigen, it just may not be adapted to actually neutralize it. Macrophages and Neutrophils are the cells that will signal and neutralize invaders.

2. Define MHC and distinguish between MHC I and MHC II and give an example of their role in immunity MHC genes are found on chromosome 6 and are an encoded MHC antigen. They have membrane proteins and differ in chemical structure and function. MHC I genes are only recognized by cytotoxic T-cells and are found on the surface of all cells. They mediate information between the white blood cells. MHC II are only recognized by helper T-cells and are only found on the surface of special immune cells. They present special antigens.

3. Compare, contrast and diagram the events associated with and the cells involved in an innate and an adaptive immune response – this will include the diagrams on T cell and B cell responses and the events associated with viral and bacterial infections For adaptive immunity, it requires several hours to several days to occur. From there inflammation occurs and either cell-mediated immunity or antibody-mediated immunity is used. For innate immunity, it is very rapid. From there, there are 6 responses. Natural barriers are already put into place and antimicrobial peptides are used, recognition receptors are used, cytokinesis occurs as well as NK cells and dendritic cells, and lastly phagocytes are involved to do phagocytosis.

4. Define and give examples of the following terms: immunology, immunity, pathogen, antigen, allergic reaction, and autoimmune disease

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5. Name and give examples of the 4 common types of antigens

6. Distinguish between pattern recognition receptors and pathogen-associated molecular patterns

7. Define innate (nonspecific) and adaptive (specific)

8. Describe defense mechanisms in invertebrates

9. Distinguish between primary and secondary lymphoid organs

10. Define and describe the process of immunocompetence and self-recognition

11. Describe an inflammatory response and what happens during inflammation

12. Name the 5 classes of antibodies and describe their location and the function of antigen-antibody complexes

13. Describe and diagram immunological memory

14. Define and describe autoimmune disease

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15. Define Rh and describe what happens during pregnancy

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