Who Killed Yew Questions PDF PDF

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Who Killed Yew assignment answers, McDermit, THHS...

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Part 1 1. The plan would involve poisoning someone. 2. Taxines are the toxic chemicals that can be isolated from the yew tree. Part 2 1. A mitotic inhibitor is a drug that inhibits mitosis, or cell division. These drugs disrupt microtubules, which are structures that pull the chromosomes apart when a cell divides. 2. The cytoskeletal elements most susceptible to mitotic inhibitors are microtubules. 3. In cell biology, mitosis is a part of the cell cycle when replicated chromosomes are separated into two new nuclei. Cell division gives rise to genetically identical cells in which the number of chromosomes is maintained. It plays an important part in the development of embryos, and it is important for the growth and development of our bodies as well. Mitosis produces new cells, and replaces cells that are old, lost or damaged. Part 3 1. Dr. Beckham only had mild symptoms because she had a small bite of the pie containing the taxine. Part 4 1. Paclitaxel is a mitotic inhibitor, which prevents cells from dividing. The microtubules, which are structures that pull the chromosomes apart when the cell divides, are disrupted. 2. Cancer is the uncontrolled growth of abnormal cells in the body. By preventing all stages of mitosis of occuring, paclitaxel could potentially stop the replication of cancer cells in the body. 3. It would be considered chemotherapy. 4. The skin and bone marrow have cells that divide rapidly. 5. Taxol would prevent normal, healthy cells from replicating. Thus, hair loss and low blood counts would occur. 6. Taxines from the yew tree are a mixture of poisons. When parts of the yew tree are ingested, the taxines include the compounds paclitaxel and taxine B. The taxine B is actually what causes death (within hours) of those poisoned. When parts of the yew tree are ingested, administration is not controlled, therefore the poison affects all parts of the body causing cell death in all cells of the body. Taxol is specifically formulated to help cancer patients. However, long-term administration to the drug would kill too many healthy cells, therefore, cancer patients cannot receive chemotherapeutic drugs indefinitely....