Ankush Sharma- bcd question corrections 306 PDF

Title Ankush Sharma- bcd question corrections 306
Author Ankush Sharma
Course Developmental Biology
Institution Hunter College CUNY
Pages 1
File Size 102.8 KB
File Type PDF
Total Downloads 60
Total Views 166

Summary

Corrections made on question...


Description

Ankush Sharma BIO 306

1) Pertaining to what was said before in my original answer, I had forgotten to give instances where such a thing (axis reversal or axis transformation/mutation) would be possible. So it can be said that if bcd is ectopically expressed in the posterior region (0%) of either of the embryos, such a thing will only be valid under the circumstance that there is a mutation in the maternal factors of an embryo which causes a downstream effect in the gap genes. If the gap genes are mutated to the point where bcd is expressed in both the anterior position and the posterior position, this will lead to changes resulting in anterior expression/regional defined borders of anterior expression being depicted in the posterior side of the given embryos. For A, B and C embryos, a distinct darkening signifying anterior expression can then be noticed in the posterior areas just as they are being expressed normally in the anterior position of the embryos. 2) If high affinity binding sites are mutated for bcd via the genes which are in the embryo, changes can be expected in the DNA sequences that are discovered upstream of the hb promoter region of gene transcription. According to ‘BicoidFigure.jpg’, differing/mutated DNA sequences can lead to possibilities where there are changes in the intensity of expression and changes in the location of the posterior boundary of expression. That is if more high affinity binding sites are noticed, a higher intensity of anterior expression will be noticed alongside a smaller portion of posterior expression in either embryos A, B, or C. If lesser high affinity binding sites are noticed, the intensity of the anterior expression will be reduced and a larger portion of posterior expression will be noticed in either embryos A, B or C....


Similar Free PDFs