ATI TEAS 6 EXAM Study Guide.docx PDF

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ATI TEAS 6 EXAM STUDY GUIDE Science Cell ➢ Cell: basic organizational unit of all living things. One thing in common is they all have membranes (phospholipids). ➢ Cell structure organization: All cells contain DNA, and RNA & can synthesize proteins. Consists of nucleic acids, cytoplasm, and cell membrane. o Tissues: Cells that are grouped together o Organs: Tissues that are grouped together o Systems: Organs that are grouped together o Organism: A complete individual ➢ Nuclear parts of a cell o Nucleus: contains chromosomes, & regulates DNA of the cell. Defining structure of eukaryotic cells (they all have nucleus). Passes genetic traits between generations. Contains nuclear envelop, nucleoplasm, nucleolus, nuclear pores, chromatin, & ribosomes. o Chromosomes: thread like rods of DNA. Short deoxyribonucleic acid, DNA is the genetic material that stores information about the plant/animal. o Chromatin: DNA & Protein makeup chromosomes o Nucleolus: Proteins, small/round doesn’t have membrane. Protein synthesis, synthesizes & stores RNA. o Nuclear envelope: Encloses structures within nucleus. Made of lipids. o Nuclear pores: Exchange materials between the nucleus * cytoplasm o Nucleoplasm: Liquid like cytoplasm, within nucleus.

Cell Membranes

➢ Cell Membrane (Plasma membrane): Semipermeable membrane of lipids and proteins. Made of phospholipid bilayer, hydrophilic ends of the outer layer facing the external environment, the inner layer facing inside the cell, hydrophobic ends facing each other. o Hydrophilic: Water loving, can dissolve water o Hydrophobic: Hates water, can’t dissolve water ➢ Selective Permeability o Selective Permeability with regards to size, charge, and solubility. ➢ Cell structure o Ribosomes: synthesize proteins from amino acids. o Golgi apparatus: synthesize materials like proteins that are transported out of the cell. Near nucleus & consists of layers of membranes. o Vacuoles: Sacs used for storage, digestion, and waste removal. One large in plant cells/ Animal cells are small or have numerous. o Vesicle: Has membrane, & can move materials within the cell. o Cytoskeleton: Microtubules that shape and support the cell. o Microtubules: Part of cytoskeleton & help support cell. Made of protein. o Cytosol: Liquid material within the cell. Mostly water & had floating materials. o Cytoplasm: Cytosol & organelles found within the plasma membrane, not within nucleus! o Cell membrane: Barrier that keeps materials out of cell. Determines what’s allowed in and out. o Rough Endoplasmic reticulum: Ribosomes on the surface, produce & store proteins o Smooth Endoplasmic reticulum: Helps store lipids & proteins.

o Mitochondrion: Generate ATP, involved in cell growth & death. Contain their own DNA aside from the one within the nucleus. ▪ Functions: Produce energy, cell signaling, cellular differentiation, cell cycle & growth regulation. Can also have aerobic respiration. ➢ Animal Cell Structure o Centrosome: Mitosis & the cell cycle occur here o Centriole: Cellular division o Lysosome: Digests proteins, lipids, and carbohydrates. Help remove undigested substances. o Cilia: Appendages that cause a cell to move & can move fluid o Flagella: Tail like structures that help the cell move. A cell usually only has one or a few flagella. Longer than cilia. ➢ Cell Cycle: Cell reproduces, growth cell, duplication of genetic material, and cell division. ➢ Cell Differentiation: Helps determine the cell type for each cell, process is controlled by genes of each cell (zygote). Following the directions of the genes, a cell builds certain proteins and other substances to set it apart as a specific type of cell. ➢ Mitosis: DNA replication & Production of new cells ▪ IPMAT=Cytokinesis o Interphase: Cell prepares to divide by replicating genetic & cytoplasmic material. (G1, S, G2) o Prophase: Chromatic thickens & nuclear membrane disintegrates. Centrioles move to opposite sides of the cells, and spindle fibers form. Mitotic spindle, formed cytoskeleton parts, moves chromosomes around the cell.

o Metaphase: Spindle moves to the center of the cell. Chromosomes align in the center.

o Anaphase: Sister chromosomes begin to pull apart. When separated they’re called daughter chromosomes. Grooves appear in the cell. Cell begins to furrow. o Telophase: Spindle disintegrates, nuclear membrane reform, and chromosomes turn into chromatin. In animal cells membrane is pinched, in plant cell a new cell wall begins to form. Splits into two. o Cytokinesis: Physical splitting of the cell.

Meiosis: Reproduction of gametes zygote o Prophase I: Parent cell's nuclear membrane begins to disappear, spindles form o Metaphase I: Chromosomes line up with homogonous chromosomes. Crossing over may occur o Anaphase I: Homogonous chromosomes are separated, so one of each goes to either side o Telophase I: Cell separates, cytokinesis occurs

o Prophase II: Almost simultaneous with Telaphase I; new spindles form and attach to centromeres

o Metaphase II: Chromosomes line up again, and some crossing over may occur o Anaphase II: Sister chromatids pulled apart at centromeres, towards poles o Telophase II: Cell separates, nuclear membranes form, cytokinesis occurs o Interphase: Diploid sex cells have double the normal chromosomes necessary Tissues ➢ Categories of Tissues o Epithelial: Cells are tightly joined. Ex. Skin o Connective: May be dense, loose, or fatty. Protects and binds body parts. Ex. Bone tissue, cartilage, tendons, ligaments, fat, blood, and lymph. o Cartilage: Cushions & provides structural support for body parts. Jelly like base and fibrous. o Blood: Blood transports oxygen to cells and removes wastes. Carries hormones and defends against diseases. o Bone: Hard tissue that supports and protects softer tissues & organs. Marrow produces red blood cells. o Muscle: Helps support and move the body. ▪ 1. Smooth ▪ Cardiac ▪ Skeletal o Nervous: Located inside the brain, spinal cord, and nerves. Neurons form network through the body that control responses to changes in the external and internal environment. Some send signals to muscles and glands to trigger responses.

Organs ➢

Mammals 1

organ systems

1) Integumentary system 2) Respiratory system 3) Cardiovascular system 4) Endocrine system 5) Nervous system 6) Immune system 7) Digestive system 8) Excretory system 9) Muscular system 10) Skeletal system 11)Reproductive system ➢ Three Primary Body Planes o Transverse (horizontal): Superior and inferior o Sagittal plane: Right and left sections. o Coronal (frontal): Front & Back {anterior & posterior} ➢ Terms of direction o Medial: toward or at the midline of the body; on the inner side of o Lateral: away from the midline of the body; on the outer side of o Proximal: closer to the origin of the body part or the point of attachment of a limb to the body trunk o Distal: farther from the origin of a body part or the point of attachment of a limb to the body trunk o Anterior: toward or at the front of the body; in front of o Posterior: Toward or at the back of the body; behind

o Cephalad=Head, Cranial=skull o Caudad=towards the tail or posterior

o Superior: toward the head end or upper part of a structure or the body; above o Inferior: away from the head end or toward the lower part of a structure or the body; below Respiratory System

➢ Upper respiratory system: Nose, nasal cavity, mouth, pharynx and larynx. ➢ Lower respiratory system: Trachea, lungs, and bronchial tree ➢ Airway: nose, nasal cavity, mouth, pharynx (throat, larynx (voice box), trachea (windpipe), bronchi, and bronchial network. o Lined with cilia, which brings debris toward the mouth o Lungs: Bronchi, Bronchial network, alveoli ▪ Alveoli: one cell thick, allow gas exchange with blood capillaries. ▪ Right lung has three lobes ▪ Left lung has two lobes, leaving room for heart. ▪ Lungs are surrounded by pleural membrane, reduces friction between surfaces when breathing. ▪ Breathing includes diaphragm & intercostal muscles.

• Diaphragm: dome-shaped muscle that separate the thoracic and abdominal cavities.

➢ Functions of the Respiratory System o Function: Supply oxygen and rid the body carbon dioxide. Exchange of gases occurs in alveoli, surrounded by blood capillaries. o Filters air. Air si warmed, moistened, and filtered as it passes through the nasal cavity. o Responsible for speech, air passes through larynx (vibrates &produces sound) before entering trachea (windpipe). o Vital in cough production, expels foreign from body. o Chemoreceptors smell airborne particles in nasal cavity. o Helps body maintain acid-base homeostasis. Hyperventilation increases blood pH during acidosis (low pH), slowing breathing during alkalosis (high pH) helps lower blood pH. ➢ Breathing process o Breathing process: Diaphragm & intercostal muscles contract to expand lungs. o Inhaling: Diaphragm contracts & moves down, increasing the size of the chest cavity. o Exhaling: Intercostal muscles contract & ribs expand, increasing size & volume in the chest cavity. Pressure inside the chest cavity decreases. o Diaphragm & intercostal muscles relax, size of the chest cavity decreases, forcing air out of the lungs. o Medulla oblongata: controls breathing process ▪ Medulla monitors level of carbon dioxide in blood, & signals breathing rate to increase when levels are too high.

Cardiovascular System ➢ Responsible for the internal transport of substances to and from cells.

o Made up of the following ▪ Blood: Blood is composed of water, solutes, and other elements in a fluid connective tissue. ▪ Blood Vessels: Tubules of different size that transport blood. ▪ Heart: Muscular pump providing the pressure necessary to keep blood flow. o Circulatory systems can be open or close. o Supplementary & Lymph clean up excess fluids & proteins & returns them to the circulatory system. o Blood: Stabilizes pH, carries raw materials & removes waste products from cells. Can fight infections. ▪ Composed of red & white blood cells, platelets & plasma. • Plasma composed of plasma proteins, ions, glucose, amino acids, hormones, & dissolved gases. o Red blood cells form in bone marrow, and transport oxygen to cells. o White blood cells defend the body against infection and remove various wastes. ▪ White blood cells include lymphocytes, neutrophils, monocytes, eosinophils, & basophils. Platelets are fragments of the stem cell & function in blood clotting. ➢ Heart o Made of cardiac muscle tissue. o Four chambers two atriums & two ventricles ▪ Halves separated by AV valves • Located between arteries & ventricles leading away from the heart. • Valves move blood in one direction, preventing it from backing into the chambers.

• Heart functions by contracting & relaxing

• Cardiac Cycle: Atrial contraction fills the ventricle & ventricular contraction empties them, forcing circulation. ➢ Systole (contracting ventricles)/ Diastole (relaxing ventricles)

Types of circulation ➢ Coronary circulation: Flow of blood to the heart tissue. o Coronary arteries: Delivers oxygen-rich blood to myocardium o Cardiac veins: Vessels that remove deoxygenated blood from heart muscle. ➢ Pulmonary circulation: Flow of blood between the heart & lungs o Carries deoxygenated blood away from the right ventricle of heart to lungs, & returns oxygenated blood to left atrium & ventricle of the heart. ➢ Systemic circulation:

o Carries oxygenated blood away from heart to the body, & returns deoxygenated blood back to the heart. Blood Pressure

➢ The pressure of blood against the arterial walls. Lymphatic System ➢ Function: The lymphatic system is to return excess tissue fluid to the bloodstream. o System consists of transport vessels & lymph organs o Lymph vascular system consist of: Lymph capillaries, lymph vessels, & lymph ducts. o Major functions of the lymph vascular systems ▪ The return of excess fluid to the blood. ▪ The return of protein from the capillaries. ▪ The transport of fats from the digestive tract. ▪ The disposal of debris & cellular waste. o Lymphoid organs: Lymph nodes, spleen, appendix, adenoids, thymus, tonsils, & small patches of tissue in the small intestine. o Lymph node: located at intervals throughout the lymph vessel system. ▪ Nodes contain lymphocytes & plasma cells. ▪ Spleen filters blood stores of red blood cells & macrophage. ▪ Thymus secrets hormones & major site of lymphocyte production. Spleen ➢ Located in the upper left of the abdomen, & behind the stomach/ below the diaphragm. o Made of lymphoid tissue. o Blood vessels are connected to spleen by splenic sinuses. ▪ Gastrolienal ligament that connects the stomach to the spleen.

▪ Lienorenal ligament that connects the kidney to the spleen ▪ Middle section of phrenicocolic ligament

o Function of the spleen is to filter unwanted materials from the blood, including red blood cells. They help fight infections. Gastrointestinal System ➢ Digestive systems function by o Movement: Mixes & passes nutrients through the system & eliminates waste. o Secretion: Enzymes, hormones, & other substances necessary for digestion are secreted into the digestive tract. o Digestive: Includes chemical breakdown of nutrients into smaller units that enter the internal environment. o Absorption: Passage of nutrients through plasma membranes into the blood or lymph & then to the body. Mouth and Stomach ➢ Digestion begins in the mouth (chewing & mixing of nutrient with saliva) o Salivary glands are stimulated & secrete saliva (amylase) o This initiates breakdown of starch in digestion. o Swallowed the food moves down the pharynx into esophagus to the stomach. ➢ Stomach is a flexible, muscular sac. Three main function include 1) Mixing and storing food 2) Dissolving & degrading food via secretions 3) Controlling passage of food into the small intestine o Protein digestion begins in the stomach. The smooth muscle (peristalsis) then moves the food into small intestine, absorption begins. ➢ Liver

o Largest solid organ & gland. Has 4 lobes. Blood flows through sinusoids. o Functions include:

▪ ▪ ▪ ▪ ▪ ▪ ▪ ▪ ▪ ▪

Production of bile. Production of certain blood plasma proteins. Production of cholesterol. Storage of excess glucose in the form of glycogen Regulation of amino acids Processing of hemoglobin (to store iron) Conversion of ammonia to urea Purification of blood Regulation of blood clotting Controlling infections by boosting immune factors & removing bacteria. ➢ Small intestine o Most nutrients are absorbed in the small intestine. o Enzymes from the pancreas, liver, & stomach are transported to the small intestine to aid digestion. Enzymes act on fats, carbohydrates, nucleic acids, & proteins. o Bile is secreted by the liver, and can break down fats. It’s stored in the gallbladder between meals. o Small intestine is covered in villi (absorb & increase surface area for interaction with chime.) ▪ Microvilli increases main absorption ➢ Large intestine o Concentrates, mixes, and stores waste material. o Absorbs water ➢ Pancreas o Made up of endocrine and exocrine tissues. o Exocrine- secretes digestive enzymes from pancreatic duct ▪ Pancreatic duct connects to the common bile duct near the duodenum. ▪ Endocrine tissue secrets hormones (insulin) into blood.

▪ Blood is supplied from splenic artery, gastroduodenal artery, & superior mesenteric artery. • Roles of Pancreas o Assists in digestion of foods by secreting enzymes, especially fats & proteins. o Precursors of enzymes (zymogens), converted to amylase & pancreatic lipase. o Secretes sodium bicarbonate to neutral stomach acid. o Exocrine functions of pancreas are controlled by hormones secreted by the stomach & duodenum. o Exocrine secretions of pancreas flow into pancreatic duct & are delivered to duodenum through pancreatic duct. ➢ Nervous System o Human nervous system senses, interprets, & issues commands o Action potential: messages sent across the plasma membrane of neurons. ▪ Messages occur when a neuron is stimulated past a necessary threshold. ▪ Stimulations occur in a sequence from one stimulation point of one neuron to its contact with another neuron. ▪ Chemical synapse: A substance released that inhibits the action of the adjoining cell. o Functional Types of Neurons ▪ Three general function of neurons are • sensory neurons, motor neurons, and interneurons. • Sensory neurons: Transmit signals to the central nervous system (CNS) from the sensor receptors

associated with touch, pain, temperature, hearing, sight, smell, & taste.

• Motor neuron: Transmits signals from the CNS to the rest of the body such as signaling muscles or glands to respond. • Interneurons: Transmit signals between neurons ▪ Neurons consist of three basic parts: • Cell body: Contains the nucleus of the of the neuron. • Axon: Transmits impulses away from cell body. It’s insulated with oligodendrocytes & myelin sheaths with gaps (nodes of Ranvier). Axon terminates at the synapse. • Dendrites: Receive impulses from sensory receptors or interneurons & transmit them toward the cell body.

Central Nervous System ➢ Spinal cord: Protects & supports the vertebrae. ➢ Brain: Consists of hindbrain, medulla oblongata, cerebellum, & pons. o Forebrain: cerebrum, thalamus, & hypothalamus. ▪ Frontal lobe: Short term & working memory, information processing, decision making, planning, & judgment. ▪ Parietal lobe: sensory input, touch, pain, pressure

▪ Occipital lobe: Visual input/output & processing. ▪ Temporal lobe: Auditory input, processing, & output.

Cerebellum: Processes & stores implicit memories. Midbrain: Visual & hearing Pons: helps control breathing Medulla oblongata: Control of consciousness and arousal; regulates breathing, cardiac functions and blood vessels diameters o Peripheral nervous system: These nerves carry information to and from the central nervous system to provide complex body functions. o Autonomic nervous system (Hypothalamus controls this): Maintains homeostasis, controls functions of the internal organs, blood vessels, smooth muscle tissue & glands. ▪ Regulates heart rate, breathing rate, body temperature, & blood pH. • Sympathetic nervous system: Controls body’s reaction to extreme, stressful, & emergency situations. “Fight or Flight” • Parasympathetic nervous system: Controls body’s homeostasis. Relaxes & inhibits high energy functions. ➢ Somatic Nervous System & Reflex Arc o Somatic Nervous System: Voluntary movement of muscles & organs, reflex movement. Voluntary movement, sensory neurons carry impulses to brain & spinal cord. ▪ Efferent (motor): Brings signals from central nervous system to sensory organs & muscles. ▪ Afferent (sensory): Brings signals from sensory organs & muscles to central nervous system. o o o o

Muscular System ➢ Three properties of muscles: o Excitability: Electric gradient can reverse when stimulated.

o Contraction: Ability to contract, or shorten. o Elongate: Share the capacity to elongate, or relax. ➢ Three types of muscle tissue: Skeletal, Cardiac, & Smooth o Skeletal muscle tissue: Composed of muscle fibers (striated muscle), Voluntary (only one that can move body). o Smooth muscle tissue: Involuntary (found in internal organs), Short/wider & nonstriated. o Cardiac muscle tissue: Involuntary muscle found only in heart. Striated ➢ Skeletal muscle contraction ➢ Made of muscle fibers: when muscle contract sarcomere contract ➢ Myofibrils: Thick filaments & Thin filaments. o Thick filament: Composed of protein myosin. o Thin filament: Composed of protein actin. ▪ Dark band: thick & thin overlapping. ▪ Light band: thin filaments overlapping. ➢ Sliding filament theory o Myosin heads hydrolyzed ATP and become reoriented and energized o Myosin heads bind to actin, forming cross bridges o Myosin cross bridges rotate toward center of the sarcomeres (power stroke) o As myosin heads bind ATP, cross bridges detach from actin

Reproductive system ➢ Male Reproductive System o Function: Produce, maintain, & transfer sperm & secrete male hormone. o Externa...