Bordenstein Friedman Bio 1510 Lecture 22 PDF

Title	Bordenstein Friedman Bio 1510 Lecture 22
Author	Madeleine Sass
Course	Intro to BioSci: Lecture
Institution	Vanderbilt University
Pages	4
File Size	54.1 KB
File Type	PDF
Total Downloads	43
Total Views	123

Preview

CLICK TO PREVIEW PDF

Summary

Specific lecture notes from class...

Description

Lecture 22 ❏ DNA + proteins = chromatin ❏ Key components of chromosomes (eukaryotes) ❏ Human chromosomes in mitosis: sister chromatids condensed ❏ DNA: dark blue (DNA dye) ❏ Centromeres: pink, have a specific DNA sequence, probe recognizes sequence, bind kinetochore proteins, provide attachment for mitotic spindle ❏ yeast= 100 base pairs of DNA to assemble centromere ❏ humans= 100s of kilobases (1000 base pairs) to assemble centromere ❏ Light blue: telomere, specific sequences found in chromosomes ❏ Mitotic and interphase chromosome organization ❏ Highly condensed, 10,000x condensed compared to naked DNA ❏ Chromosomes visible ❏ Probes- single stranded DNA, can distinguish diff strands with diff colors ❏ interphase nucleus ❏ Much more decondensed ❏ Chromosomes have “territories” ❏...