Che 327 year 2021/2022 PDF

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Summary

syllabus of this year Physics 131 syllabus year 2021 with professor Hemmick. All assignments and grading material...

Description

Organic Chemistry Laboratory/Department of Chemistry Last updated Aug 18th, 2021 Important Note: Every effort will be made to avoid changing the course schedule, but the possibility exists that unforeseen events will make syllabus changes necessary. It is your responsibility to check Blackboard for corrections or updates to the syllabus. Any changes will be clearly noted in course announcements or through Stony Brook email.

Part 1: Course Information

Fall 2021 CHE 327

Prerequisite: CHE 133; CHE 134 or CHE 154. Pre- or Corequisite: CHE 321 or 331. Lab director: Dr. Sajjad Hossain [email protected]

Lecturer: Professor Kathlyn Parker [email protected]

Office: CHEM 511

Office: CHEM 707

Office Hours: By appointments

Office Hours: Will be announced during the first week

Lecture (In-person Mondays FREY HALL 102 WESTCAMPUS 11:45 AM-12:40) Labs: Mo 1:00PM - 4:50PM. 11:50AM

Tu 8:00AM - 11:50AM. Tu 1:15PM - 5:05PM. We 9:15AM - 1:05PM. Th 8:00AM -

Office hours of the teaching assistants will be posted early in the semester. We urge you to use these scheduled times to discuss the techniques and experiments with any CHE 327 staff member. Course Description: This is a one-semester, 2-credit course that provides an organic laboratory experience. It includes techniques of isolating and handling organic substances, as well as biological materials. The lecture will be synchronous and will be uploaded to the blackboard for those who are registered for the online version. The two theory quizzes will be administered in-person for everyone during the scheduled lecture time (Oct 4th and Nov 15th from 11:45-12:40 PM). Labs will be conducted within the course schedule meeting time. Regular announcements will be sent from Blackboard. These will be posted on the course site and will be sent by email. These announcements will include updates made in your electronic lab manual, any new posting in the blackboard site and other important course related information. You are expected to check these announcements regularly and any other announcements made on the blackboard. In-Person Communication: Dr. Hossain will be available at the start of each lab sessions (unless otherwise announced) to take quick questions. This will be the best way for you to clarify anything related to the course. For personal/private issues, email Dr. Hossain directly to set up a meeting.

CHE 327

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You are encouraged to attend Professor Parker's office hours regularly since this will be the best way to communicate any concerns you have regarding the course lecture. Attend the graduate TA office hours for general lab related questions. You are allowed to go to any graduate TA’s office hour, not just your own.

Lab Safety, PPE and Required Electronic Lab Manual/Notebook: Face Masks/Coverings: Everyone participating in this class, must wear a mask/face covering at all times. Any student not in compliance with this will be asked to leave the class. ● CHE 327 Electronic Lab Manual Fall 2021 edition. This will be purchased electronically from the LabArchives, which comes as a bundle of an Electronic Laboratory Manual and Notebook (ELN). To sign up for CHE 327 ELN, please visit the link: https://mynotebook.labarchives.com/self_signup/ MjQ0NjQuN3wwLzE4ODE5L0NvdXJzZS83MTQzNjQxMTh8NjIxMDIuNw== You must purchase the ELN before the first day of classes to submit assignments. You must use your stony brook email address to sign up for the ELN. Once you receive access to your ELN, you must purchase it to use the ELN. ● Splash resistant Safety goggles that follow the latest Z87.1 Standard for Occupational and

Educational Eye and Face Protection established by ANSI. Make sure that the google you purchase prevents splash and not safety glasses. You are expected to have your own goggles during the first in-person lab. ● Heavy-duty gloves. Lab Safety Supply Neoprene Gloves are recommended as they resist a

broad range of organic and inorganic chemicals. Playtex Living Gloves are also satisfactory and probably the cheapest available. They can be found at a grocery store or home improvement store. ● Nitrile gloves (not required but recommended). Disposable gloves to keep your hands clean

when conducting experiments. They can be found at any superstore or home improvement store. ● Combination padlock. This will be used to lock your lab drawer. A padlock requiring a key to

open it will not be accepted. ● Appropriate clothing for the lab. You should wear clothing and shoes that will cover your entire body. Do not wear clothing made of synthetics as these may dissolve or degrade if exposed to organic solvents. You will be provided a lab coat during check-in, which you will be required to wear during the lab. The specifics are covered in the lecture/safety video. Failure to adhere to the personal protection safety rules will result in an automatic absence and/or grade penalty.

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● Read the Laboratory Safety Chapter (Chapter 1 from the introduction in your Lab Manual sections folder) for more on safety.

Email: Your Stony Brook University email must be used for all University-related communications. You must have an active Stony Brook University email account and access to the Internet. All instructor correspondence will be sent to your SBU email account. Plan on checking your SBU email account regularly for course-related messages. To log in to Stony Brook Google Mail, go to http://www.stonybrook.edu/mycloud and sign in with your NetID and password. If you use Blackboard’s email tool from the course site, it will automatically include your full name, course name and section when you send an email. If you are not emailing using your blackboard, make sure to include this information in your subject. Please allow between 24-48 hours for an email reply.

Technical Requirements: This course uses Blackboard for the facilitation of communications between faculty and students, submission of assignments, and posting of grades and feedback. The Blackboard course site can be accessed at https://blackboard.stonybrook.edu If you are unsure of your NetID, visit https://it.stonybrook.edu/help/kb/finding-your-netid-and-password for more information. You are responsible for having a reliable computer and Internet connection throughout the term. Caution! You will be at a disadvantage if you attempt to complete all coursework on a smartphone or tablet. It may not be possible to submit the files required for your homework assignments. Students should be able to use email, a word processor, spreadsheet program, and presentation software to complete this course successfully. The following list details a minimum recommended computer set-up, and the software packages you will need to have access to, and be able to use: ● ● ● ● ● ●

● ● ● ● ●

PC with Windows 10 or higher (we recommend a 3-year Warranty) Macintosh with OS 10.11 or higher (we recommend a 3-year Warranty) Intel Core i5 or higher 250 GB Hard Drive 8 GB RAM Latest version of Chrome or Firefox; Mac users may use Chrome or Firefox. (A complete list of supported browsers and operating systems can be found on the My Institution page when you log in to Blackboard.) High speed internet connection Word processing software (Microsoft Word, Google Docs, etc.) Headphones/earbuds and a microphone Webcam (recommended) Printer (optional) 3

CHE 327

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● Ability to download and install free software applications and plug-ins (note: you must have administrator access to install applications and plug-ins). Technical Assistance: If you need technical assistance at any time during the course or to report a problem with Blackboard you can: ● Phone: 631-632-9800 (client support, Wi-Fi, software and hardware) ● Submit a help request ticket: https://it.stonybrook.edu/services/itsm ● If you are on campus, visit the Walk-Up Tech Support Station in the Educational Communications Center (ECC) building. ELN Support: If you need technical assistant with your electronic lab manual/notebook (Labarchives) contact labarchives support: [email protected]

Part 2: Course Learning Objectives and Assessments The objective of this course is for students to learn different techniques for isolating and analyzing pure organic compounds in relatively high yield while adhering to safety protocols and maintaining scientific record. Students will be able to follow standard safety protocols of chemical handling and laboratory etiquette. This learning objective is evaluated by assessing the in-person lab technique. Students will learn the skill of recording observations and writing detailed procedures. This learning objective is evaluated by ELN quizzes that assess what they have recorded in their lab notebooks. Upon the completion of this course, students will perform experiments involving standard synthetic laboratory techniques such as small-scale crystallization, large scale crystallization, melting point, solid-liquid extraction, rotary evaporation, liquid-liquid extraction, TLC, microcolumn chromatography, reflux, and distillation. This learning objective is evaluated by assessing the quality of products (both yield and purity) submitted by the students. Students will be able to analyze the purity of products, calculate retention factors, and calculate percent recovery/yield with accuracy. This learning objective is evaluated by assessing lab reports, lecture quizzes, and theory quizzes.

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Part 3: Course Schedule

Week

Assignments

To

Week 1

23-Aug

26-Aug

Week 2 Week 3

30-Aug Safety Voucher Due 6-Sep

2-Sep 9-Sep

LAB (In-Person) Lecture (In-person Mondays Report in front of Chemistry Room 344 FREY HALL 102 WESTCAMPUS (Organic Chemistry Stockroom) 11:45 AM-12:40) Mondays-Thursdays Check-in: Must report for check in. Failure to Safety/Lab Policy check-in will result in deregistration. Check your goggles, ELN email address At the start: Show proof of your Safety Crystallization Voucher submission to your TA EXP: Crystallization of Benzoic Acid Labor Day Labor Day

Week 4

13-Sep Safety & ELN Report DUE

16-Sep

Trimyristin

At the start: Submit your Benzoic Acid Product EXP: Trimyristin from ground Nutmeg ELNQ1 will be posted on the labarchives at the end of the week along with the weekly announcements.

Week 5

20-Sep Crystallization Report & ELNQ1 DUE

23-Sep

Myristic Acid

At the start: Submit your Trimyristin Product EXP: Myristic Acid ELNQ2 will be posted on the Labarchives

Week 6

27-Sep Trimyristin Report and ELNQ 30-Sep 2 DUE

TLC (isomerization)

At the start: Submit your Myristic acid product TLC (isomerization) At the end: Submit your TLC Plate ELNQ 3 and 4 will posted on the labarchives

7-Oct

Theory Quiz 1 for all students. Mon Oct 4 (11:45-12:40 PM)

EXP: Isolation of Beta Carotene At the end: Submit Beta Carotene TLC Plate ELNQ5 will be posted on the Labarchives

14-Oct

Fall Break No class

Fall Break No lab

21-Oct

Column Chromatography and Simple Distillation

EXP: Simple distillation ELNQ6 will be posted on the Labarchives

28-Oct

Ester Synthesis

EXP: Ester synthesis

4-Nov

Spectroscopy/GC /IR

EXP: Ester Purification and Analysis ELNQ7 will be posted on the Labarchives

11-Nov

Lidocaine Synthesis NMR

EXP: Lidocaine Synthesis

Theory Quiz 2 for all students. Nov 15 (11:45-12:40 PM)

EXP: Lidocaine Purification (workup) ELNQ8 will be posted on the Labarchives

4-Oct Myristic Acid Week 7 Report, TLC Report, ELNQ 3 and ELNQ 4 DUE Week 8 11-Oct 18-Oct Beta Carotene Week 9 Report and ELNQ 5 DUE 25-Oct Simple Distillation Week 10 Report and ELNQ 6 DUE Week 11 1-Nov 8-Nov Week 12 Ester Report and ELNQ 7 DUE Week 13 15-Nov

18-Nov

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CHE 327

Week 14 22-Nov

Fall 2021

25-Nov

29-Nov Lidocaine Week 15 Report and ELNQ 2-Dec 8 DUE

From beta carotene to Lidocaine including NMR Thanksgiving No Class Nov 29 Makeup Theory Quiz* A permission must be granted from Dr. Hossain to attend the makeup theory quiz.

Thanksgiving No Lab At the Start: Submit your Lidocaine Product EXP: Makeup/Catch up Lab**/Check out A permission must be granted by Dr. Hossain to complete makeup lab

Part 4: Grading (Subject to minor adjustments) Lecture

100

Theory Quiz 1 Theory Quiz 2

50 50

Lab

300

ELNQ 1

12 Safety and ELN Report

10 Products & Techniques 0 10 Product 1: Benzoic Acid

ELNQ 2

12 Crystallization Report

10 Product 2: Trimyristin

10

ELNQ 3

12 Trimyristin Report

10 Product 3: Myristic Acid

10

ELNQ

Crystallization of BA Extraction of trimyristin Myristic Acid Synthesis TLC (Isomerization) Beta Carotene Simple distillation Ester Lidocaine

100 Reports

100 5

ELNQ 4

12 Myristic Acid Report

10 Product 4: TLC plate

10

ELNQ 5

12 TLC (Isomerization Report)

10 Product 5: Column & TLC plate

10

ELNQ 6

12 Beta Carotene Report

10 Product 6: Ester

15

ELNQ 7

12 Simple Distillation Report

10 Product 7: Crude and Purified Lidocaine

15

ELNQ 8

16 Ester Report

15 Lab Technique

25

Lidocaine Report

15

Course Total The letter grade cutoffs are generally as what it shows in this table A AB+ B BC+ C CD+ >=372 >=360 >=348 >=332 >=320 >=308 >=292 >=280 >=268 Minor adjustments are made based on the class average which is usually set to a high B.

400

D >=240

F...