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MTX Theophylline● G toxicity ● Liver Toxicity ● Blood disorder ● Pulmonary ToxicationToxicity:● HYPERGLYCAEMIA ● HYPOKALAEMIA ● Eyes (Dilated pupils) ● Haematemesis ● Agitation ● Convulsion ● Sinus tachycardia ● Cardiac arrhythmiaDigoxin Amiodarone● Cardiac● Neurological : ○ Lethargy, dizziness ○ G ...

Description

MTX

Theophylline Toxicity:

● ● ● ●

G.I toxicity Liver Toxicity Blood disorder Pulmonary Toxication

● ● ● ● ● ● ● ●

Digoxin

HYPERGLYCAEMIA HYPOKALAEMIA Eyes (Dilated pupils) Haematemesis Agitation Convulsion Sinus tachycardia Cardiac arrhythmia

Amiodarone

● Cardiac

● Hyper/Hypo thyroid

● Neurological : ○ Lethargy, dizziness ○ G.I disturbances

● Impaired Vision ○ (corneal deposit) ● Photophobia

● Visual ○ blurred/yellow vision

● Phototoxic ● Neurological symptoms ○ (tremor, numb)

Ciclosporin ● ● ● ● ● ●

Blood disorder Liver toxicity Neurotoxicity Gingival Hyperplasia HTN Headache

Tacrolimus ● ● ● ● ● ● ● ●

Nephrotoxicity Skin disorder Neurotoxicity Blood disorder Eye disorder Liver toxicity HYPERGLYCAEMIA CV Disorder

CBZ

Phenytoin

● Blood disorder ● Skin disorder ● Hepatic disorder ● Toxicity: ○ Incoordination, ○ blurred vison, ○ diplopia(double vision), ○ drowsiness, ○ Ataxia ○ Hyponatremia

● ● ● ● ●

Lithium

Agranulocytosis Blood disorder Skin disorder Vit D deficiency Suicidal thoughts

● Toxicity: ○ Ataxia, speech ○ HYPERGLYCAEMI A

● Antiepileptic Hypersensitivity Syndrome ○ (rash, fever, swollen nodes

Vancomycin ● REDMAN SYNDROME ○ Flushing of upper body ● ● ● ● ●

Nephrotoxicity Ototoxicuty Skin disorder Blood disorder Phlebitis (irritation of tissue)

● if given quickly: ○ HYPOTENSION and ○ Anaphalytic

Gentamicin ● Nephrotoxicity ● Ototoxicity ● Skin disorder

● ● ● ● ●

G.I disturbance CNS disturbance Visual Disturbance Fine tremor Incontines, Polyuria

● >2+ Severe Overdosage ○ Hypothyroidism only ○ HTN...