Immunity Worksheet PDF

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Immunity WORKSHEET

Write the type of immunity beside each clinical example. Possible choices include: active, passive. 1. Neonate does not develop an infection because he has maternal antibodies that he received in breast milk. 2. Child does not develop an infection because she has been immunized against it. 3. Man does not develop an infection because he was infected with that same microorganism previously and recovered. 4. Woman does not develop an infection because she was given gamma globulin after being exposed to an infected person. 5. Look at the labels on the graph. Does this graph pertain to the innate immune system or the adaptive immune system?

6. Which curves rise sooner after exposure to antigen, those in section A or section B? 7. Why do the curves you identified rise sooner after antigen exposure?

8. Sequence the vascular events that occur during inflammation. Write the letters here in the correct order of the steps: __________________________ A. Local edema B. Brief vasoconstriction C. Increased vascular permeability D. Leakage of plasma into tissues E. Vasodilation 9. What one word describes what these cells are doing?

10. After these cells have left the blood vessel, what directs them to the site of tissue injury?

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Immunity WORKSHEET

Complete this table by filling in the empty boxes. Characteristics of Immune Defenses Barrier function of Inflammatory function Adaptive innate immunity of innate immunity immunity 11. How soon does this defense begin working after first contact with a pathogen? 12. Does this defense remember the pathogen and act more rapidly upon subsequent exposure? 13. Does each component of this defense work against many different antigens (nonspecific) or only one antigen (specific)? 14. Innate resistance or immunity: a. involves “memory.” b. is a development of an individual’s later years. c. is a relatively slow and specific process. d. depends on physical, mechanical, and biochemical barriers. 15. Complement is: a. a series of proteins in the blood. b. an antibody. c. a hormone. d. a lymphokine. 16. Diapedesis is a process in which: a. neutrophils migrate from the bloodstream to an injured tissue site. b. phagocytes stick to capillary and venule walls. c. bacteria are “coated” with an opsonin. d. there is oxygen-dependent killing of cells. 17. The inflammatory response: a. prevents blood from entering the injured tissue. b. elevates body temperature to prevent spread of infection. c. prevents the formation of abscesses. d. minimizes injury and promotes healing

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Immunity WORKSHEET

18. The sequence for phagocytosis is: a. margination or pavementing, recognition of the target, adherence or binding, fusion with lysosomes inside the phagocyte. b. diapedesis, margination or pavementing, phagosome formation, recognition of the target, fusion with lysosomes inside the phagocyte. c. recognition of the target, margination, destruction of the target by lysosomal enzymes. d. margination, diapedesis, recognition, adherence, ingestion, fusion with lysosomes inside the phagocyte, destruction of the target. 19. Swelling during acute inflammation is caused by: a. collagenase. b. the fluid exudate. c. lymphocytic margination. d. neutrophilic margination. 20. CD4 markers are associated with: a. cytotoxic T cells. b. suppressor T cells. c. helper T cells. d. APCs. 21. Antibodies are produced by: a. B cells. b. T cells. c. helper cells. d. plasma cells. 22. The primary immune response involves: a. a rapid plasma cell response with peak antibody levels by 3 days. b. macrophage production of antibodies. c. T cell production of antibodies. d. a latent period 23. Which is not characteristic of hypersensitivity? a. specificity b. immunologic mechanisms c. inappropriate or injurious response d. prior contact unnecessary to elicit a response 24. When the body produces antibodies against its own tissue, the condition is called: a. a hypersensitivity. b. an antibody reaction. c. a cell-mediated immunity. d. an autoimmune disease.

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Immunity WORKSHEET

25. Which hypersensitivity is caused by poison ivy? a. type I b. type II c. type III d. type IV 26. A positive HIV antibody test signifies that the: a. individual is infected with HIV and likely so for life. b. asymptomatic individual will absolutely progress to AIDS. c. individual is not viremic. d. sexually active individual was infected the previous weekend. 27. Which is incorrect regarding AIDS? a. Antibody usually appears within 4 to 7 weeks after infection. b. The patient will be anti-HIV. c. The patient will likely experience opportunistic infections and cancer. d. The patient will have increased numbers of CD4+ cells or helper T cells. 28. Which of the following characterizes the alarm stage? a. Increased lymphocytes b. Increased sympathetic activity c. Increased parasympathetic activity d. Increased eosinophils 29. Which of the following is true? a. Stressors initially stimulate the adrenal cortex. b. Stressors stimulate immunity. c. The emotions of fear, anxiety, and grief can act as stressors. d. Stressors are the same for all individuals. 30. The production of cortisol in response to stress can be initiated by: a. the hypothalamus, anterior pituitary, and adrenal cortex. b. the hypothalamus, posterior pituitary, and adrenal cortex. c. the hypothalamus, sympathetic nerve fibers, and adrenal cortex. d. the hypothalamus, sympathetic nerve fibers, and adrenal medulla.

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Immunity WORKSHEET

Answer Key 1. Passive 2. Active 3. Active 4. Passive 5. Adaptive immune system 6. B 7. Memory cells respond quicker to a previously experienced antigen 8. B E C D A 9. Diapedesis 10. They move by chemotaxis to the area where the chemotactic cytokines are in the highest concentration. 11. Already working before pathogen contact; Very rapidly; After some delay 12. No; No; Yes 13. Many different antigens; Many different antigens; only one antigen 14. D 15. A 16. A 17. D 18. D 19. B 20. C 21. C 22. D 23. D 24. D 25. D 26. A 27. D 28. B 29. C 30. A

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