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Action Potential

Charles Sevigny Physiology Department [email protected]

1

Ionic constituents (Textbook values)

Silverthorn 4th Edition Table 8-2

2

Let’s Review…. Equilibrium Potential – K+

Sherwood Fig: 3-26, page 89

3

Classifying changes in Membrane Potential

Sherwood Fig: 4-1, page 100

4

Graded Potential changes

Sherwood Fig: 4-2, page 101

5

Current Flow during Graded Potential changes

Sherwood Fig: 4-3, page 101

6

Current Flow during Graded Potential changes

Sherwood Fig: 4-3, page 101

7

Current Flow during Graded Potential changes

Sherwood Fig: 4-3, page 101

8

Current loss across the plasma membrane

Sherwood Fig: 4-4, page 102

9

Decremental spread of graded potentials

Sherwood Fig: 4-5, page 102 10

Changes in MP during an Action Potential

Sherwood Fig: 4-6, page 103 11

Voltage-gated sodium channel

Sherwood Fig: 4-7, page 104 12

Positive Feedback of Na+ channels

Sherwood Fig: 4-8, page 105 13

Voltage-gated potassium channel

Sherwood Fig: 4-7, page 104

14

Movements of Ions during an Action Potential

Sherwood Fig: 4-9, page 106

15

Movements of Ions during an Action Potential

Sherwood Fig: 4-9, page 106

16

Movements of Ions during an Action Potential

Sherwood Fig: 4-9, page 106

17

Movements of Ions during an Action Potential

Sherwood Fig: 4-9, page 106

18

Movements of Ions during an Action Potential

Sherwood Fig: 4-9, page 106

19

Movements of Ions during an Action Potential

Sherwood Fig: 4-9, page 106

20

Movements of Ions during an Action Potential

Sherwood Fig: 4-9, page 106

21

Movements of Ions during an Action Potential

Sherwood Fig: 4-9, page 106

22

Permeability changes and Ion fluxes during an AP

Sherwood Fig: 4-10, page 107

23...