Neuro Exam questions - Past exam PDF

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11 SECTION B Neurophysiology, NEUR3221 2014 final exam

Name of Candidate: Student ID:

Write the answer to this question only on the lined part of this sheet. Remember: only answer 4 of the 6 questions in this section.

ii.

In the CNS, non-neuronal cells are essential to brain function, explain the contribution of different classes of non-neuron cells to inter-neuronal communication [5 marks].

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13 SECTION B Neurophysiology, NEUR3221 2014 final exam

Name of Candidate: Student ID:

Write the answer to this question only on the lined part of this sheet. Remember: only answer 4 of the 6 questions in this section. Question B2 Describe the afferent and efferent innervation of the cochlear hair cells, including the location of the neuron cell bodies for these sensory and motor pathways in the cochlea and brainstem. Indicate the cell targets of the afferent and efferent axons - a schematic diagram may be used to support this. Indicate the principal neurotransmitter utilized by the hair cells, and the principal transmitter used by the efferent fibres. [10 marks].

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15 SECTION B Neurophysiology, NEUR3221 2014 final exam

Name of Candidate: Student ID:

Write the answer to this question only on the lined part of this sheet. Remember: only answer 4 of the 6 questions in this section. Question B3 i.

ii. iii.

Describe the role of the receptors the classical model of long-term potentiation (LTP). Explain how the properties of each receptor type enable them to perform this function [5 marks] Explain how stimulation of the amygdala alters the induction of LTP in the hippocampus [2 marks] Explain the cellular mechanisms through which cocaine and marijuana act to increase dopamine levels in the nucleus accumbens [3 marks].

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17 SECTION B Neurophysiology, NEUR3221 2014 final exam

Name of Candidate: Student ID:

Write the answer to this question only on the lined part of this sheet. Remember: only answer 4 of the 6 questions in this section. Question B4 i. ii.

Design an optogenetic experiment that would achieve similar outcome to the Fluoxetine treatment [5 marks].

iii.

Discuss the factors that prevent your optogenetic approach from being used as a current treatment option [2 marks].

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19 SECTION B Neurophysiology, NEUR3221 2014 final exam

Name of Candidate: Student ID:

Write the answer to this question only on the lined part of this sheet. Remember: only answer 4 of the 6 questions in this section. Question B5 You are making

from two single units in primary somatosensory

cortex. One unit has a receptive field on the palm of the left hand; the other has its receptive field on the wrist of the left arm. i. ii. iii. iv.

v.

How would you determine if the units were rapidly adapting? How could you use the activity of the neurons to determine whether the peripheral stimulus was a skin vibration? How could you use the activity of the neurons to determine if there are two separate sources of skin vibration, or one common source overlapping both receptive fields? Do you think that psychophysically it would be an easier or harder task to make a two point discrimination judgement with vibrating or with static stimuli? Explain your reasons. Describe where and why the activity from your two units might converge onto a single neuron elsewhere in the brain.

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21 SECTION B Neurophysiology, NEUR3221 2014 final exam

Name of Candidate: Student ID:

Write the answer to this question only on the lined part of this sheet. Remember: only answer 4 of the 6 questions in this section.

Your left eye has has suffered extensive photoreceptor degeneration. You have had bionic eye surgery in the left eye and had a 24 x 24 electrode epiretinal array implanted that covers the central third of your retina. Vision through your right eye is normal. Describe and explain any differences in the quality of vision through your normal and your 'bionic' eye under the following conditions: i. ii. iii. iv. v.

low light (outdoors on a moonless night) appreciating a colourful artwork tracking a moving stimulus reading very fine print Discuss any differences in the organization of your visual cortex that might be apparent if you had the bionic implant inserted at age 5, compared with later in adult life at age 50 (assuming that your vision loss in the left eye occurred only at age 45).

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