Pharmacology Chapter 2 Assignment PDF

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Pharmacology study guide chapter two...

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Pharmacology Chapter 2 Activities To make sure that you have learned the key points covered in this chapter, complete the following activities. True or False Write true if the statement is true. Beside the false statements, write false and correct the statement to make it true. 1. Cumulation means a drug causes disease False, cumulation is medication build up in the body. _________________________________________________________________________ 2. An antagonist blocks a drug from being effective. True._____________________________________________________________________ _________________________________________________________________________ 3. A drug’s half-life is the time needed to decrease the drug’s plasma concentration by 50%. True._____________________________________________________________________ _________________________________________________________________________ 4. Psychotropic drugs can cross the blood-brain barrier. _True____________________________________________________________________ _________________________________________________________________________ 5. Anticancer drugs do not cross the blood-placental barrier.

False, anticancer drugs are teratogenic drugs, meaning they cross the blood-placenta barrier and cause birth defects. _________________________________________________________________________ 6. Ototoxicity can damage the eyes. False, it can cause damnage to hearing and balance. ______________________________________________________________________ ______________________________________________________________________

7. Idiosyncratic means safe for children. False, idiosyncratic means unique raction. _________________________________________________________________________ 8. The primary organ of metabolism is the kidneys. False, the liver is the primary organ with megabolism. _________________________________________________________________________ _________________________________________________________________________ 9. A package insert is a valuable source of information about medications. ______True.__________________________________________________________________ ____________________________________________________________________________ 10. BUN is a blood test looking at the function of the kidneys. _____True.___________________________________________________________________ ____________________________________________________________________________ Multiple Choice Choose the best answer for each question. 1. Which term means leaving the body? A. B. C. D. E.

Absorption Biotransformation Distribution Excretion Metabolism

2. Which term means moving through membranes? A. B. C. D. E.

Absorption Biotransformation Distribution Excretion Metabolism

3. Which term means chemical alteration to another substance in the body? A. B. C. D.

Absorption Biotransformation Distribution Excretion

4. Which term means moving of the medication from the site of administration to the target organ? A. B. C. D.

Absorption Biotransformation Distribution Excretion

5. Where does ototoxicity occur? A. B. C. D. E.

Eyes Ears Liver Kidneys Brain

6. Where does nephrotoxicity occur? A. B. C. D. E.

Eyes Ears Liver Kidneys Brain

7. Which of the following are sources of information about medications? A. B. C. D. E.

PDR (Physicians’ Desk Reference) USP/DI USP/NF Package insert All of the above

8. Which term means the point at which a medication has the optimal desired effect? A. B. C. D.

Therapeutic level Therapeutic range Toxic level None of the above

9. Agonists are taken together to: A. B. C. D.

Interact with or counteract each other Work together Cause great pain Relieve great pain

10. The section of the PDR that is a product identification guide is the: A. White section

B. Pink section C. Blue section D. Gray section Short Answer Questions Answer these questions in the space provided. 1. Why would the physician order you to give an antagonist? _A physician would order an antagonist if the effects of an administered drugs needs to be reversed. ______________________________________________________________________

2. Why can a drug be toxic to a fetus without hurting the mother? ______________________________________________________________________ ______________________________________________________________________ ________________________

3. Why should a patient abstain from operating heavy equipment if he or she is given a narcotic for nausea and vomiting? ______________________________________________________________________ ______________________________________________________________________ _______________________

4. Why would a physician give two different drugs at subtherapeutic levels? ______________________________________________________________________ ______________________________________________________________________ ________________________

5. The cabinet with all the drug resources is locked, and the key cannot be found. Where can you find out about an ordered medication before administering it? ______________________________________________________________________ ______________________________________________________________________ ________________________ Application Exercises Respond to the following situations in the space provided. 1. Mary is taking a blood thinner. She does not understand why she needs to have blood drawn monthly. How would you educate her?

______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ __________________________________

2. Daniel has cirrhosis of the liver. How may this affect his metabolism of drugs? ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ____________________________________

3. Butler is coming in for a flu shot into the muscle. He insists that he wants the injection in his arm, not his buttocks. Both his arms are covered in tattoos. What would you do? ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ____________________________________

4. Rose has diabetes. Because of her diabetes, she has increased blood pressure and kidney problems. How does this affect the distribution and elimination of drugs from her body? ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ____________________________________

5. Jerry, an older patient, comes in with a paper bag containing assorted pills. He is not sure which he is supposed to be taking. What would you do? ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ____________________________________

6. You draw blood from Gary to check compliance with drug therapy, but laboratory results show none of that drug in his blood. What could be happening? What would you do? ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ____________________________________

Vera complains that she hears ringing in her ears ever since starting a new drug. What is this called, and what could be causing this?...