Physio Ex Exercise 9 Activity 1 PDF

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4/20/2021

PhysioEx Exercise 9 Activity 1

PhysioEx Lab Report Exercise 9: Renal System Physiology Activity 1: The Effect of Arteriole Radius on Glomerular Filtration Name: Titus Aina Date: 20 April 2021 Session ID: session-135eaa6d-c322-fb53-5407-2981c175b248

Pre-lab Quiz Results You scored 100% by answering 5 out of 5 questions correctly. 1 There are approximately __________ nephrons in a healthy human kidney. You correctly answered: 1 × 10 6 2 Which of the following lists the anatomical structures in the correct order as they are encountered by the blood itself during the process of filtration? You correctly answered: afferent arteriole, glomerular capillary, efferent arteriole. 3 Bowman's capsule is connected to the beginning of the You correctly answered: proximal convoluted tubule. 4 The functional unit of the kidney is the You correctly answered: nephron. 5 During the process of renal reabsorption, fluid and solutes move from the You correctly answered: renal tubule into the peritubular capillaries.

Experiment Results Predict Questions 1 Predict Question 1: What will happen to the glomerular capillary pressure and filtration rate if you decrease the radius of the afferent arteriole? Your answer: Both pressure and filtration rate will decrease. 2 Predict Question 2: What will happen to the glomerular capillary pressure and filtration rate if you increase the radius of the afferent arteriole? Your answer: Both pressure and filtration rate will increase.

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PhysioEx Exercise 9 Activity 1

3 Predict Question 3: What will happen to the glomerular capillary pressure and filtration rate if you decrease the radius of the efferent arteriole? Your answer: Both pressure and filtration rate will decrease. Stop & Think Questions 1 Caffeine consumption leads to increased urine formation. From the results in this experiment thus far, you might propose that You correctly answered: caffeine dilates the afferent arteriole. 2 When you are in the desert and dehydrating, which of the following arteriole combinations would benefit you the most? You correctly answered: afferent constriction and efferent dilation. Experiment Data Afferent Radius (mm)

Efferent Beaker Press. Radius (mm) (mm Hg)

Glomerular Press. (mm Hg)

Glom. Filt. Urine Volume Rate (ml/min) (ml)

0.50

0.45

90

55.08

124.99

200.44

0.45

0.45

90

51.54

81.06

179.88

0.40

0.45

90

48.52

43.66

143.91

0.35

0.45

90

46.16

14.35

76.33

0.55

0.45

90

58.94

172.86

212.87

0.60

0.45

90

62.88

221.69

220.74

0.50

0.45

90

55.08

124.99

200.44

0.50

0.40

90

56.10

137.69

227.49

0.50

0.35

90

56.84

146.82

247.96

0.50

0.30

90

57.34

152.96

262.23

Post-lab Quiz Results You scored 100% by answering 4 out of 4 questions correctly. 1 If you increase the afferent arteriole radius and keep all other variables constant, the glomerular filtration rate would You correctly answered: increase. 2 If you decrease the efferent arteriole radius and keep all other variables constant, the volume of urine flowing into the urinary bladder would

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PhysioEx Exercise 9 Activity 1

You correctly answered: increase. 3 If you increase the efferent arteriole radius and keep all other variables constant, the glomerular filtration rate would You correctly answered: decrease. 4 If you decrease the afferent arteriole radius and keep all other variables constant, the volume of urine flowing into the urinary bladder would You correctly answered: decrease.

Review Sheet Results 1 What are two primary functions of the kidney? Your answer: The kidneys two major functions are to excrete and regulate. pH and BP is influenced by the kidney also. 2 What are the components of the renal corpuscle? Your answer: Bowman's capsule and glomerulus are the components. 3 Starting with the renal corpuscle, list the components of the renal tubule as they are encountered by filtrate. Your answer: First, the proximal convoluted tubule, second, the loop of Henle and third, the distal convoluted tubule. 4 Describe the effect of decreasing the afferent arteriole radius on glomerular capillary pressure and filtration rate. How well did the results compare with your prediction? Your answer: When decreasing the afferent arteriole radius on glomerular capillary pressure, both the glomerular pressure and filtration rate will decrease, as I predicted in my experiment. 5 Describe the effect of increasing the afferent arteriole radius on glomerular capillary pressure and filtration rate. How well did the results compare with your prediction? Your answer:

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PhysioEx Exercise 9 Activity 1

Opposite to the decreasing of afferent arteriole radius, the increase will make both increases. They are connected in that way. The result was a good compartment to my prediction. 6 Describe the effect of decreasing the efferent arteriole radius on glomerular capillary pressure and filtration rate. How well did the results compare with your prediction? Your answer: When efferent arteriole radius is decreased, the glomerular capillary pressure and filtration rate will both increase. In this case, the changes in efferent radius will give an opposite result in pressure and filtration rate. This was a good comparishment to my predictions. 7 Describe the effect of increasing the efferent radius on glomerular capillary pressure and filtration rate. Your answer: An increase in efferent radius will decrease both capillary pressure and filtration rate. With an increased radius, the blood will be able to flow faster out of the glomerular and decrease filtration rate(less urine is produced), and the pressure will drop when the blood volume is decreased.

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