Prednisone (Deltasone) PDF

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ACTIVE LEARNING TEMPLATE:

Medication

STUDENT NAME _____________________________________

prednisone (Deltasone), fluticasone (Advair) MEDICATION __________________________________________________________________________

17 REVIEW MODULE CHAPTER ___________

anti-inflammatory, glucocorticoid CATEGORY CLASS ______________________________________________________________________ PURPOSE OF MEDICATION

Expected Pharmacological Action - Prevent inflammation, suppress airway mucus production, and promote responsiveness of beta2 receptors in the bronchial tree - Reduction in airway mucosa edema - The use of glucocorticoids does not provide immediate effects, but rather promotes decreased frequency and severity of exacerbations and acute attacks.

Therapeutic Use -

Short-term IV agents are used for status asthmaticus. Inhaled agents are used for long-term prophylaxis of asthma. Short-term oral therapy is used to treat manifestations following an acute asthma episode Long-term oral therapy is used to treat chronic, severe asthma. Promote lung maturity and decrease respiratory distress in fetuses at risk for preterm bir

Complications - Suppression of adrenal gland function - Bone loss - Hyperglycemia and glycosuria - Myopathy - Peptic ulcer disease - Infection - Disturbances of fluid and electrolytes (Fluid retention as evidenced by weight gain, and edema and hypokalemia as evidenced by muscle weakness)

Medication Administration Prednisone: oral only Fluticasone: Inhalation

Contraindications/Precautions - Pregnancy Risk Category C - Contraindicated in clients who have received a live virus vaccine and those who have systemic fungal infections. - Use cautiously in children, and in clients who have diabetes mellitus, hypertension, heart failure, peptic ulcer disease, osteoporosis, and/or kidney dysfunction.

Interactions - Concurrent use of potassium-depleting diuretics increases the risk of hypokalemia. - Concurrent use of NSAIDs increases the risk of GI ulceration. - Concurrent use of glucocorticoids and hypoglycemic agents (oral and insulin) counteract the effects.

Evaluation of Medication Effectiveness - Long-term control of asthma - Resolution of acute exacerbation as demonstrated by absence of shortness of breath, clear breath sounds, absence of wheezing, and return of respiratory rate to baseline

ACTIVE LEARNING TEMPLATES

Nursing Interventions - Monitor weight, blood pressure, and electrolytes. - Give with food to reduce gastric distress - Assess patient for signs of adrenal insufficiency (hypotension, weight loss, weakness, nausea, vomiting, anorexia, lethargy, confusion, restlessness) before and periodically during therapy

Client Education - Do not stop the medication suddenly. Taper dosage if discontinuing. Stopping the medication suddenly may result in adrenal insufficiency - Advise clients to observe for indications of peptic ulcer (coffee-ground emesis, bloody or tarry stools, abdominal pain) - Instruct clients to use glucocorticoid inhalers on a regular, fixed schedule for long-term therapy of asthma. Glucocorticoids are not to be used to treat an acute episode.

THERAPEUTIC PROCEDURE

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