Quiz for Module 4 PDF

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Actual module MCQ, some used in the actual exam...

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Practice Questions for Module 4: Neurotransmitter Disease What statement regarding generalised anxiety disorder (GAD) is FALSE? Has a high comorbidity with major depressive disorder

It is linked with physiological symptoms, such as muscle tension

It has a relapsing-remitting course Correct! Tends to develop in adolescence

Question 2 1 / 1 pts How were the monoamine neurotransmitters initially implicated in bipolar disorder? Correct! Low norepinephrine, dopamine and serotonin linked to depressive symptoms

Low serotonin only accounts for mania and depression

High dopamine and low norepinephrine linked to depressive symptoms High norepinephrine, dopamine, and serotonin linked to mania

Question 3 0 / 1 pts What line of evidence provides support for the monoamine hypothesis of major depressive disorder (MDD)? Serotonin has consistently and widely been found to be low in the CSF of patients experiencing MDD

Polymorphisms in the gene encoding the serotonin transporter have been associated with depression

Selective serotonin reuptake inhibitors decrease serotonin availability leading to reduced mood You Answered Compounds that stimulate monoamine oxidase inhibitor improve mood

Question 4 1 / 1 pts What do Bipolar I and Bipolar II disorder have in common? Both have the same severity of manic and depressive symptoms

The two are characterised by periods of hypomania

They effect males and females equally orrect! The severity of depressive symptoms is consistent between the two

Question 5 1 / 1 pts What statement regarding brain-derived neurotrophic factor is FALSE? Peripheral immune dysfunction can reduce BDNF expression

Low levels of BDNF are associated with depression

BDNF maintains and enhances dendritic branching Correct! BDNF production is increased by cortisol

Question 6 0 / 1 pts What role does GABAergic neurotransmission play in anxiety? High GABA in the amygdala causes symptoms

You Answered Benzodiazepines are agonists of the GABA-A receptor

GABA is excitatory Increasing activity at the GABA-A receptor improves symptoms

Question 7 1 / 1 pts The dopamine hypothesis of schizophrenia: Correct! Now asserts that the mesocortical pathway is underactive

Can explain all the symptoms of schizophrenia

States that dopamine signalling is broadly low

Has remained unchanged since its inception

Question 8 1 / 1 pts Epigenetics refers to: Correct! The environment causing a change that influences gene expression without the code being altered

The study of genetic risk factors for mental health conditions A single point mutation in the genetic code passed down from a parent

DNA methylation increasing gene expression

Question 9 0 / 1 pts Cognitive impairment is required for diagnosis of schizophrenia.

You Answered True False

Question 10 1 / 1 pts Changes in brain activity in schizophrenia can be directly seen using what technique/s? Correct! EEG and fMRI

Post-mortem tissue analysis

Electroencephalography (EEG) only

Functional magnetic resonance imagining (fMRI) only...