Title | Review OSCE Cases |
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Course | Pharmacy Practice |
Institution | University of Sydney |
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Revision of basic paediatrics ailments are what the mains points and referral points...
RTS Paediatrics Common childhood ailments: 1. Fever 2. Chicken pox 3. Headlice 4. Oral thrush 5. Nappy rash 6. Colic 7. Threadworm
Management for ailments 1. Fever
Fluid: Prevent dehydration. Happens more rapidly in children Appropriately dressed for surroundings Antipyretics
Paracetamol & Ibuprofen
Not used together. If still distressed before next dose is due try the other.
Paracetamol >2 months (page 4)
Ibuprofen >3 months (page 9)
*Fever may be a symptom of meningitis, to eliminate meningitis, ask about the following symptoms; tense or bulging soft spot on the head, high temperature, breathing fast/ difficulty breathing, cold hands and feet, blotchy skin (getting paler or turning blue), pin prick rash, extreme shivering.
2. Chicken Pox
Highly contagious, common illness that mainly affects children. o Caused by varicella zoster virus. o Itchy, spotty rash. o Symptoms appear 1 to 3 weeks after becoming infected. o Main symptoms; EARLY SYMPTOMS: fatigue, high temp, nausea, headache, aching muscles, loss of appetite. (not universal – older children and adults) SPOTS – red raised spots develop on the face or chest before spreading to other parts of the body. BLISTERS – over the next few hours, very itchy fluid filled blisters develop on top of the spots. SCABS & CRUSTS – after a further few days the blisters dry out and scab over to form a crust. The crusts then gradually fall off by themselves over the next week or two.
Treatment o
Management options include painkillers, antipyretics and antipruritics.
o
Painkillers and Antipyretics
Paracetamol NOT IBUPROFEN: Due to increased risk of secondary bacterial skin complications. Lotions and creams
Calamine (Antipruritic) Cooling gels
Antihistamines
Chlorphenamine (Piriton)
3.Headlice DRY COMBING 1. Straighten and untangle dry hair using normal comb. 2. Switch to a detection comb. 3. Starting form back of head, comb the scalp from the scalp down to the end of the hair. 4. After each stroke examine the comb for live lice. 5. Continue to comb all hair in sections until the whole head has been combed. 6. The process can take 5 mins or more in people with shoulder length hair.
WET COMBING 1. Wash hair with normal shampoo. 2. Apply hair conditioner. 3. Repeat steps 1-5 as for dry combing. 4. Rinse out the conditioner.
*Wet combing is more time consuming and should be performed for all family members. *
Treatment Options Over 6 months: Permethrin, Dimeticone, Malathion Over 2 years: Isopropyl myristate
4. Oral Thrush Potential causes; recent antibiotics use/ recent course of antibiotics used by mothers, immature immune system, steroid inhaler use, inhaled corticosteroids
Typically, patients present with patches that are irregular and vary in size that are difficult to remove
Usually causes some pain
Often effects tongue and cheeks
It is unusual in otherwise healthy adults – a healthy adult with no risk factors requires referral
Treatment (over 4 months) is with Daktarin.
4-24 months 1.25ml QDS (four times a day) after meals.
Adult risk factors: Diabetes Dry mouth Immunocompromised Ill-fitting dentures Recent antibiotics Inhaled corticosteroids
2 yrs+ 2.5ml QDS
5.Nappy Rash Preventative measures:
Change wet/dirty nappies ASAP.
Clean whole nappy area gently, wiping from front to back, using water or fragrance free and alcohol-free baby wipes. Bath baby daily – not more than twice a day as may cause skin to dry out. Dry baby gently after washing. Leave nappy off for as long an as often as possible to let fresh air get to the skin. Do not use soap, bubble bath or lotions. Do not use talcum powder as it can irritate babies skin. Preventative measures:
o o o
Leave nappy off as long as possible each day Avoid using soaps for cleaning Change nappies as soon as they have been soiled
Treatment: Apply barrier cream – after each nappy change Eliminate infection – clotrimazole
6.Colic
Conditions to eliminate Acute infection – fever, no history of excessive crying Intolerance to cow’s milk protein – not as common as people think Gastro-oesophageal reflux disease – regurgitation >5x per day, failure to gain weight, refusal to feed
Treatment/Management of colic
Holding baby during crying episodes. Sitting or holding upright during feeding. Use fast-flow teat if breastfeeding – holes in bottles that are too small may cause baby to swallow air as they feed.
Burping baby after feeds.
Don’t drink too much tea, coffee and other caffeine drinks if breastfeeding.
Avoid overstimulation of baby by continually picking them up and putting them down.
Babies like movement e.g gentle rocking over the shoulder.
Background noise e.g. white noise may be soothing.
Gentle stomach or back rubs or a warm bath may help.
Treatment:
None have a credible evidence base however parents generally want to give something a try. Lactase enzymes - Colief Simeticone - Infacol
7.Threadworm o
More common in school and pre-school children but still can infect adults
o
Transmitted most commonly by the faecal-oral route; eggs get lodged under finger nails
o
Eggs are very hardy and can easily be transferred to clothing, bed linen etc resulting in dust-borne infection
o
Clinical features: Night-time perianal itching caused by mucus produced by females when laying eggs Can range from local ‘tickling’ sensation to acute pain
o
Conditions to eliminate: Other worm infections: round- and tape- worm infections usually contracted by adults visiting poor and developing countries Contact irritant dermatitis: no recent history of infection, no visible signs of worms in faeces
Treatment Hygiene measures: (lifespan of threadworm approx 6 weeks) Strict attention to hygiene needed Nails kept short and clean Careful hand washing and nail scrubbing prior to meals and after each visit to the toilet Wash bed linen regularly – ideally every day Don’t share towels Underwear underneath night clothes Shower daily immediately on rising Damp dusting and daily vacuuming
Mebendazole for > 2years – whole family should be treated! Repeated dose after 14 days if re-infection suspected
Antihistamines OTC Medicines used to treat; o
allergies
o
reactions to insect bites or stings
o
motion sickness
o
nausea related to migraine
o
short term treatment for sleeping difficulties.
Usually divided into two main groups;
1st Generation (Drowsy) Cross blood-brain barrier (BBB) – Chlorphenamine (Piriton), Diphenhydramine (Nytol), Promethazine (Phenergan), Buclizine (found in combination in Migraleve) 2nd Generation (Non-drowsy) Do not cross BBB– Loratadine (Clarityn), Cetirizine, Acrivastine (Benadryl Allergy Relief)
Rhinorrhea Runny nose with a discharge that is thin, clear and watery Nasal congestion Inflammatory response to allergen that causes vasodilation and congestion Nasal itching Eye symptoms Eyes may be itchy and watery. Result of tear duct congestion and pollen grain caught in the eye Sneezing Classic response is sneezing then rhinorrhoea then congestion
Management/ Treatment of Hay fever symptoms
Wearing wraparound sunglasses to stop pollen getting in your eyes when outdoors. Taking a shower and changing clothes after being outdoors. Staying in doors when pollen count is high (>50 grains per cubic metre of air) Keeping windows closed when pollen count is high – particularly morning and evening. Apply a small amount of pertroleum gel to nasal openings to trap pollen grains. Don’t keep fresh flowers in the house. Vacuum regularly – high-efficiency particle arresting (HEPA) filter. Damp dust. Avoid cutting grass, playing or walking in grassy areas. Keep car windows closed - pollen filter can be bought for air vents in cars.
Medications Antihistamines
Steroid nasal sprays Sodium cromoglicate Decongestants Referral Criteria; wheezing, purulent conjunctivitis, earache and facial pain.
Motion Sickness
Non- drugs: Ginger, wrist straps Drugs: Antihistamines
Symptoms:
nausea +/- vomiting dizziness pallor cold sweats hypersalivation
a/e and c/i as per hyoscine Cinnarizine - min. age 5 years - intermediate-acting (up to 8 hours)
Promethazine - min. age 2 years - long-acting (longer than 8 hours)
Insomnia Treatment/Medication Sleep Hygiene Drug(Antihistamine) diphenhydramine
Pharmacological Interventions Sedating Antihistamines: Promethazine Diphenhydramine Sleep Hygiene Avoid sleeping in warm rooms and drinking alcoholic/caffeine drinks. Associate bed with sleep only No naps, maintain a routine and if you cannot sleep get up to do something then go back to sleep.
Eyes
Referral; Under 12 Duration >3 weeks No known cause Previous undiagnosed medical conditions Symptoms suggestive of anxiety or stress
1. Conjunctivitis Viral – sticky pus, feel gritty i. Self-limiting therefore no treatment. ii. Hygiene measures to prevent spread to others as highly contagious i.e not sharing towels, washing hands etc. Allergic – red and watery iii. Mast cell stabilisers, antihistamines and sympathomimetics. (SEE RTS ANTIHISTAMINES MATERIAL) Bacterial iv. Brolene and Golden eye 1. >12 years 2. 1-2 drops up to four times daily 3. If no improvement within 2 days see GP v. Chloramphenicol eye drops/ointment 1. >2 years 2. Drops – 1 drop every 2 hrs for 48hrs followed by 4 times daily for 5 days. 3. Ointment – alone apply 4 times daily, or once daily at night if used with drops.
2. Blepharitis Common condition characterised by red, swollen eyelids. Additional symptoms; a. Itchy sore eyelids b. Crusty / greasy eyelashes c. Gritty burning sensation d. Abnormal eyelash growth or loss of lashes
Management Daily cleaning routine which includes; •
Using warm compress
•
Massaging eyelid gently
•
Cleaning eye lids (cooled boiled water and cotton buds)
3. Dry Eye Carbomer
Hypromellose & Carmellose
Polyvinyl
Treatment Options Wool Fats
Sodium Hyaluronate Refer if doesn’t clear up in 2 weeks. (GP)
Ears
Excessive Ear Wax What is ear wax? A normal secretion from the ear canal from ceruminous glands Purpose of ear wax: -Protects tympanic membrane -Trap foreign particles and dust, protects lining of canal -Repel water -Bactericidal and fungicidal activity
Two main types 1.Wet, honey to dark brown 2.Dry, grey and flaky If there is too much ear wax, the patient can experience temporary deafness or hard of hearing in the ear(s) affected. Wax normally migrates to outer ear – ‘self cleaning’ when it accumulates in the external auditory canal it can form a “ plug” Ear wax can build up in all but especially: people with lots of hair in the ear, those with narrow ear canals, people who use ear plugs/hearing aids and the elderly (wax becomes drier). Treatment for excess ear wax; Cerumenolytics Fixed and volatile oils (Olive oil, Almond oil, Arachis (peanut) oil, Earex®, Cerumol®) Docusate sodium (Waxsol®)
Na+ bicarbonate Urea, hydrogen peroxide (Exterol®, Otex®) Wax softening agents can be used by all, no interactions Don’t use cotton buds
How to use More comfortable if the drops are warmed (room temp) first Hold in hands or place in warm (not hot) water Lie down with the affected ear uppermost Gently pull pinna back and up (pull down and back in children) to open the ear canal Place correct number of drops into ear canal Stay in position for about 5 min
Referral Criteria Trauma / history of surgery Foreign body in ear canal Where OTC treatments have failed – will need syringing Ringing or dizzy sensation Severe pain / earache Fever and malaise in children Presence of discharge
Otitis externa Inflammatory condition of the pinna or outer ear canal – skin swells / tender to touch. Becomes chronic if it lasts for more than 3 months.
Symptoms
Pain Discharge Itch / irritation External ear + / or canal appears red, swollen, or eczematous Deafness No systemic symptoms
Predisposing factors Ear trauma Use of cotton buds / ear trauma Syringing Dermatitis Chemicals (e.g. shampoo, hair dyes)
Excess moisture (e.g. frequent swimming) Humid environments
Treatment
Diffuse OE
Choline salicylate (Earex Plus®) Acetic acid e.g. Earcalm®
Furunculosis
Hot flannel Oral analgesics
Referral criteria Ear pain in children Inflammation of pinna Unsuccessful treatment Impaired hearing Mucopurulent discharge
Oral antibiotics if severe
Otitis Media Can affect one or both ears, 75% cases in children under 10 yrs where 1 in 4 children has OM before 10 yrs. Peak incidence – between 3 – 6 years.
OM Symptoms
Earache (Otalgia) Discharge (Otorrhoea) if tympanic membrane perforates (sometime relieves pain, heals naturally) Children feel unwell Hot, irritable, sleeplessness, ear pulling / rubbing, crying child – could be ear infection Temporary deafness – conductive Fever Red / yellow / cloudy / bulging TM on examination
OM Treatment Most (80%) cases in children resolve within 3 days with no treatment Aim is to reduce severity and duration of pain and other symptoms and prevent complications Analgesia – e.g. paracetamol, ibuprofen
If severe or does not ease after 2-3 days may need Antibiotics (refer)
Referral Criteria
Recurrent infections No improvement in 3 days
Women’s Health 1.Cystitis o
Infections of the urinary tract are especially common in women
o
Peak incidence early 20’s
SYMPTOMS o
‘Itching’ of urethra indicates an attack
o
Urgency & Frequency
o
Dysuria (discomfort/burning sensation when passing urine) – classical symptom
Treatment Analgesics e.g. paracetamol and ibuprofen
Refer: Longer than 7 days Women over 70 Children under 16 Diabetics Hematuria Men Immunocompromis ed Pregnancy Vaginal discharge Associated fever
Potassium and sodium citrate (symptomatic) to reduce acidity of urine– Low Evidence Antimicrobial therapy, where indicated, is highly effective, for first line therapy. Cranberry Juice – Low Evidence Empty bladder completely Use a hot water bottle – holding a hot water bottle on your tummy or between your thighs may reduce any discomfort Don't have sex until you're feeling better, because it may make the condition worse
Prevention Void the bladder completely when urinating Avoid delay in emptying the bladder After bowel motions, wipe from front to back If sexual intercourse seems to be a trigger, wash the peri-anal skin beforehand empty the bladder before and after
Use a lubricant to prevent trauma and soreness Avoid tight underwear made from synthetic materials and tight trousers Thoroughly rinse out detergent after washing clothes Avoid perfumed bath additives and vaginal deodorant Reduce intake of coffee and alcohol.
2.Vaginal Thrush o
Pruritus (Itch) often intense and burning in nature
o
Vaginal discharge is usually, but not always, present (a good diagnostic aid)
o
Discharge varies from watery to a creamycoloured, thick discharge
o
Discharge is odourless
o
Dysuria (pain on urination)
o
Dyspareunia (painful intercourse)
o
Treated without examination by GP but persistence indicates that a swab should be taken therefore REFER back
Refer: Discharge that has a strong smell Diabetes Treatment failure Under 16s and over 60s Pregnancy Recurrent attacks Immunosuppressed
Treatment Fluconazole 150mg
o o
Internal o
Pessary – 500mg pessary with applicator o
Intravaginal cream; 5g of 10% clotrimazole
Avoid wearing nylon underwear and tights Do not use vaginal deodorants, foam baths or perfumed soaps Recurrent symptoms require medical referral Topical imidazoles can damage latex condoms and diaphragms
and/or External cream; 2% Clotrimazole cream
3.Dysmenorrhoea o
Most common in adolescents and women in their 20s
o
Pain is usually described as cramping
o
Pain is rarely severe
o
Onset occurs shortly before the onset of menses and rarely lasts for more than 3 days
Refer: Heavy or unexplained bleeding Pain experienced before menses or if it increases after menses Signs of systemic infection Bleeding in postmenopausal women Women over 30 with new/worsening symptoms
Treatment NSAIDS - Ibuprofen - Naproxen HYOSCINE; motion sickness and postoperative nausea and vomiting
4.Menorrhagia o
Heavier than normal bleeding (more than 60 mls)
o
It can interfere with normal activities
o
Can occur with other symptoms
o
Need to be able to exclude sinister pathology
o
Medication related?
Medication Anticoagulants MAOIs Cimetidine Steroids Thyroid hormones
Referral Intermenstrual bleeding Pelvic pain Post coital bleeding/pain Treatment failure
GI Tract
Ulcers Minor ulcers Last 5 – 14 days crops of one to five White or yellowish centre with an inflamed red outer edge Refer: Duration of longer than 3 weeks Associated weight loss Rash Suspected ADR Diarrhoea Treatment Chlorhexidine mouthwash Local Analgesics Local Anesthetics
Major aphthous ulcers (REFER) 30mm in diameter Crops of up to 10
Cold Sores Key points : Infection caused by herpes simplex virus (HSV1) Symptoms: o o o o o
Prodromal symptoms of itching, burning, tingling pain Occur a few hours to a couple of days before lesion Lesion appears as blister and associated redness These crust over within 24 hours resolve in 7-10 days
Treatment: Antivirals – acyclovir, penciclovir Ammonia and Phenol (Blistex®) Urea – (Cymex®)
Heartburn Symptoms Burning discomfort experienced in the upper part of the stomach Aggravating factors: 1. Bending or lying down 2. Obesity 3. After a large meal
Treatment
Referral ALARM symptoms Anaemia Loss of weight Anorexia Recent onset of progressive symptoms Melaenia, dysphagia & haematemesis Severe pain Persistent vomiting Pain radiating to arm, neck & jaw Failure to respond to antacids – 1 week
Antacids – neutralise acid Alginates – raft forming H2 antagonists Proton Pump Inhibitors – most effective Practical points: Food – small meal...