Rifampin drug card PDF

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Summary

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Description

ACTIVE LEARNING TEMPLATE:

Medication

White STUDENT NAME Taylor _____________________________________ MEDICATION rifaminpin __________________________________________________________________________ REVIEW MODULE CHAPTER ___________ CATEGORY CLASS antituberculars ______________________________________________________________________

PURPOSE OF MEDICATION

Expected Pharmacological Action Rifampin is bactericidal as a result of inhibition of protein synthesis

Therapeutic Use Rifampin is a broad-spectrum antibiotic effective for gram-positive and gram-negative bacteria. - Rifampin is given in combination with at least one other antituberculosis medication to help prevent antibiotic resistance

Complications dysfunctionDiscoloration of body fluids Hepatotoxicity (jaundice, anorexia, and fatigue) Mild GI discomfort Pseudomembranous colitis

Medication Administration PO IV

Contraindications/Precautions Use cautiously in clients who have liver dysfunction Nursing Interventions

Interactions

Monitor liver function Administer oral rifampin 1 hr before or 2 hr after meals. Absorption is decreased if given with food

Rifampin accelerates metabolism of warfarin, oral contraceptives, protease inhibitors, and non-nucleoside reverse transcriptase inhibitors (NNRTIs) for HIV, resulting in diminished effectiveness Concurrent use with isoniazid and pyrazinamide increases risk of hepatotoxicity - Avoid alcohol consuption

Client Education Evaluation of Medication Effectiveness Improvement of tuberculosis manifestations, such as clear breath sounds, no night sweats, increased appetite, and no afternoon rises of temperature - Three negative sputum cultures for tuberculosis, usually taking 3 to 6 months to achieve

ACTIVE LEARNING TEMPLATES

Advise clients to use a non-hormonal form of contraception - Instruct clients to avoid alcohol consumption...