Silodosin Drug Study PDF

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Summary

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Description

Drug Study

Generic Name: silodosin

Trade

Name(s): Rapaflo

Drug Classification: Therapeutic:benign prostatic hyperplasia - enlarged prostate (BPH) agents Pharmacologic: alphaadrenergic blockers Therapeutic Uses: Decreased signs and symptoms of BPH (urinary urgency, hesitancy, nocturia).

Maximum Dosage/24 hours: 8 mg PO once daily

Possible Routes of Administration: PO

Usual Dosage and Frequency: 8 mg once daily This Patient’s Dose and Frequency:

Mechanism of Action: Blocks post synaptic alpha1-adrenergic receptors. Decreases contractions in the smooth muscle of the prostatic capsule.

Adverse Effects: dizziness, headache, orthostatic hypotension, diarrhea, retrograde ejaculation, pruritis, rash, urticaria, allergic reactions

Nursing Implications: •

Assess patient for symptoms of benign prostatic hyperplasia (urinary hesitancy, feeling of incomplete bladder emptying, interruption of urinary stream, impairment of size and force of urinary stream, terminal urinary

dribbling, straining to start flow, frequency, dysuria, nocturia, urgency) before and periodically during therapy. •

Assess patient for orthostatic reaction and syncope. Monitor BP (lying and standing) and during initial therapy and periodically thereafter.

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Rule out prostatic carcinoma before therapy; symptoms are similar.

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Administer with food at the same meal each day

Patient Teaching: •

Instruct patient to take medication with the same meal each day.

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May cause dizziness. Caution patient to avoid driving or other activities requiring alertness until response to the medication is known.

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Caution patient to avoid sudden changes in position to decrease orthostatic hypotension, especially patients with low BP or concurrently taking antihypertensives.

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Instruct patient to notify health care professional of all Rx or OTC medications, vitamins, or herbal products being taken and consult health care professional before taking any new medications, especially cough, cold, or allergy remedies.

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Instruct patient to notify health care professional of medication regimen before any surgery. Patients planning cataract surgery should notify opthalmologist of silodosin therapy prior to surgery.

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Inform patient that silodosin may cause retrograde ejaculation (orgasm with reduced or no semen). This does not pose a safety concern and is reversible with discontinuation.

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Emphasize the importance of follow-up exams to evaluate effectiveness of medication.

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Geri: Assess risk for falls; implement fall prevention program and instruct patient and family in preventing falls at home....