Test 1 blueprint (updated 7 PDF

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Pharmacology exam one concepts modules 1-3....

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NUR2474 Test # 1 Review Please review general tips from the Quiz review document (test-taking strategies, select all that apply questions, etc.). The test will utilize the Respondus browser and monitor (using webcam). No notes or textbooks are allowed on the test. The calculator will be enabled in the browser.

General tips for studying: 1. Memorize medication categories from the presentation (SSRI’s, benzodiazepines-can be used in seizurez, first/second-generation antipsychotics, etc.) used to treat common neuro conditions (PD, Alzheimer’s disease, BPD, ADHD, etc.)- ssri withdraw graduately. Benzo/barb tapper of 2. Memorize essential drugs from the categories above (there are many questions with specific drug names) 3. Use generic names 4. When reviewing particular drugs, note category, indications, typical side efects, toxicity signs (if applicable) 5. Barbituates toxicity= ending barbital = active echarcle for benzo toxicity give flunazinile. Benzo= good first line

Topics to review: 1. TCA overdose S/S and management- cardiac symptoms including death, constipation, drowniness 2. Clonazepam (indications, side/adverse efects, patient teaching, nursing interventions)antiepileptic cant stop or change dose, withdraw slowly. 3. Lithium therapy (blood testing, therapeutic levels, toxicity levels, side efects, toxic efects)- low sodium with make you accumulate lithium in the blood. 4. BPD patients on Lithium and adjunct meds for mania/depression 5. Benzodiazepines and alcohol withdrawal6. Alprazolam therapy and anxiety 7. Treatment of anxiety patients with sedative/hypnotics 8. Main points for first-, second-generation, and atypical antipsychotics (including main adverse efects) 9. Fluoxetine (indications, side/adverse efects, patient teaching, nursing interventions)- SSRI, 10. Methylphenidate (Ritalin) therapy in children 11. Donepezil (Aricept) therapy in pt’s with Alzheimer’s disease – delay the progression(indications, side/adverse efects, patient teaching, nursing interventions)- bronchospasm12. Review therapy discontinuation for depression 13. Sertraline (Zoloft) and nursing infants 14. Duloxetine (Cymbalta) and alcohol abuse 15. Diazepam (Valium) for status epilepticus (seizures) 16. The intended efect, teratogenic efect, paradoxical efect, tolerance 17. Atypical antipsychotic drug administration, time frames, reasons for 18. Phenytoin and pregnancy, therapeutic level(10-20mcg/ml), adverse/side efects, indications, nursing interventions, patient education- antiseizure, may mess with contraceptives and cause tertigenesis careful with pregnancy 19. Carbamazepine therapeutic level, indications 20. EPS and drugs that cause them

21. Amitriptyline overdose, side efects (other TCAs) 22. Neuroleptics and PD patients 23. The half-life of medications (why important to know, how does it afect administration frequency, how to calculate the amount of the drug in the system)- if life is 24 hours it takes a while to metabolize which means doses will be spaced out, drug x has HL of 8hr, if I gave 1000mg at 8am how much drug will remain in blood in 24hr? = 4pm= 500 by 12pm=250 8am=125 . 24. MAOI’s and tyramine 25. Neuroleptic malignant syndrome (signs, causing meds and treatment) 26. Patient teaching for medication therapy in general (safety, compliance, etc.)- liver and kidneys, check their functions is drug excrtied by them. 27. Levodopa/Carbidopa in PD (action, side efects, interventions for side efects)- increase water and salt intake to decrease likelihood of orthostatic pressure. Know why given together- caridopa helps levodopa stay in body longer and more efective HELP DEAL WITH PARKINSON SYMPTOMS MORE EFFECTIVELY 28. Cholinesterase inhibitors and indications, side efects, cardiac efects 29. Interferon-beta therapy (indications, side/adverse efects, patient teaching, nursing interventions)- flu like symptom, to assess for suicde reports anything even depression report 30. Oxcarbazepine therapy and antidiuretics 31. Lamotrigine (indications, side/adverse efects, patient teaching, nursing interventions)- antiseizue medication, 32. Baclofen therapy 33. Lisdexamfetamine (indications, side/adverse efects, patient teaching, nursing interventions) 34. Tardive dyskinesia as an adverse efect of meds35. Antidotes to common meds... (you should memorize all antidotes we mention in lectures) 36. ADHD treatment goals- insomnia, lose of appetite, normalizes the behavior to point where child can focus and pay attention, give after breakfast in 37. Parkinsonism as an adverse efect of meds- cant slow down, can only manage the symptoms 38. The nursing process as it relates to med administration 39. Drug metabolizing and eliminating organs- kidney and liver 40. Receptor binding (agonist, antagonist, partial agonist)- agonist= works with/causes, antagonist= works against/blocks 41. Memorize therapeutic levels for, Valproic Acid=50-100mcg, Lithium0.6-1.2mmol/L 42. Dependence vs. tolerance vs. addition/abuse- tolerance=need more meds/higher to achieve same efect, dependence=needs tapered of, addiction/abuse need the medication or will have withdraws. 43. Hypertensive crisis, MAOIs, tyramine44. Benzodiazepine—EMERGENCY ANXIETY SITUATION IV. – FIRST LINE FOR SLEEPING PROBLEMS (SIMPLE INSOMNIA SHOOULD BE SHORT TERM)and barbiturate overdose management 45. Flumazenil WITH BENZO OVERDOSE 46. First-generation vs. second-generation antipsychotics- one way to treat movement adverse efects would be give anticholertic med 47. Emergency treatment of psychosis (types of the antipsychotic, first-generation, second generations, atypical antipsychotics) 48. ANTICHOLENERGIC EFFECT- CARDIAC EFFECT...